多发性骨髓瘤肾损害早期诊断标志物的研究进展
Research Progress on Biomarkers in Early Diagnosis of Renal Impairment in Multiple Myeloma
DOI: 10.12677/ACM.2021.113193, PDF,   
作者: 刘莹莹:青岛大学,山东 青岛;刘雪梅*:青岛大学附属医院肾病科,山东 青岛
关键词: 多发性骨髓瘤肾损害生化标志物早期诊断研究进展Multiple Myeloma Renal Impairment Biomarkers Early Diagnosis Research Progress
摘要: 多发性骨髓瘤(Multiple myeloma, MM)是血液系统常见的恶性肿瘤,骨髓中浆细胞产生大量的异常单克隆免疫球蛋白,可对全身多个脏器造成损害。肾脏损害(Renal impairment, RI)是其较为严重的并发症,因此寻找MM早期肾损害相关分子标志物,进行早期诊断是提高MM患者生活质量及其生存率的最重要的措施之一。本文对MM肾损害相关早期诊断标志物的研究进展进行综述。
Abstract: Multiple myeloma (MM) is a common malignant tumor in the blood system. Plasma cells in the bone marrow produce a large number of abnormal monoclonal immunoglobulins, which can cause damage to multiple organs in the body. As a serious complication of Renal Impairment (RI), it is one of the most important measures to improve the quality of life and survival rate of MM patients to search for biomarkers in early diagnosis of Renal Impairment in Multiple Myeloma. This review summarizes the research progress of biomarkers in early diagnosis related to renal impairment in patients with Multiple Myeloma.
文章引用:刘莹莹, 刘雪梅. 多发性骨髓瘤肾损害早期诊断标志物的研究进展[J]. 临床医学进展, 2021, 11(3): 1353-1361. https://doi.org/10.12677/ACM.2021.113193

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