电化学生物传感器检测外泌体的研究进展
Research Progress of Electrochemical Biosensor for Detecting Exosomes
DOI: 10.12677/WJCR.2021.112005, PDF,    科研立项经费支持
作者: 朱俊芳, 薛 雯, 唐立红, 陈洁晶, 陈 燕*：中国人民解放军联勤保障部队第九二四医院检验科/广西代谢性疾病研究重点实验室，广西 桂林
关键词: 外泌体；电化学生物传感器；肿瘤生物标志物；Exosome； Electrochemical Biosensors； Tumor Biomarkers
摘要: 早期发现、早期诊断是改善肿瘤患者的预后、提高生存率最重要的手段。肿瘤衍生的外泌体是肿瘤早期诊断和预后评估的新型生物标志物。在这里，我们回顾了用于检测肿瘤来源外泌体电化学生物传感器的最新研究进展。主要包括外泌体潜在标志物可用于生物传感器设计的指示性靶标，生物识别元件和信号转换技术。此外，还分析了电化学生物传感技术检测肿瘤来源外泌体所面临的挑战和机遇。
Abstract: Early detection and diagnosis are the most important means to improve the prognosis and survival rate of tumor patients. Tumor-derived exosomes are new biomarkers for early tumor diagnosis and prognosis evaluation. Here, we review the latest research progress of electrochemical biosensors for detecting tumor-derived exosomes. It mainly includes potential exosomes markers that can be used as indicative targets for biosensor design, biometric identification elements and signal conversion technology. In addition, the challenges and opportunities for the detection of tumor exocrine bodies by electrochemical biosensor technology were also analyzed.
文章引用：朱俊芳, 薛雯, 唐立红, 陈洁晶, 陈燕. 电化学生物传感器检测外泌体的研究进展[J]. 世界肿瘤研究, 2021, 11(2): 33-37. https://doi.org/10.12677/WJCR.2021.112005

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