小儿推拿对咳嗽变异性哮喘缓解期患儿IL-4、IL-13、γ-干扰素的影响

Effect of Pediatric Tuina on IL-4, IL-13 and γ-Interferon in Children with Cough Variant Asthma in Remission

摘要: 目的：研究小儿推拿对咳嗽变异性哮喘缓解期患儿IL-4、IL-13、IFN-γ的影响。方法：通过随机选择咳嗽变异性哮喘缓解期患儿60例，治疗组30例，以小儿推拿治疗；对照组30例，给予药物孟鲁司特钠治疗。观察治疗前后患儿血清IL-4、IL-13、γ-干扰素的改变。结果：治疗组总有效率 93.33%；对照组总有效率73.33%。将两组进行比较有统计学意义(P < 0.05)。治疗前后血清IL-4、IL-13、IFN-γ的比较，治疗组IL-4、IL-13的降低值优于对照组，治疗组IFN-γ的升高值优于对照组，有统计学意义(P < 0.05)。结论：小儿推拿治疗咳嗽变异性哮喘缓解期效果优于孟鲁司特钠组。

Abstract: Objective: To study the effect of pediatric massage on IL-4, IL-13 and IFN-γ in children with cough variant asthma in remission. Methods: Randomly select 60 children with cough variant asthma in remission, and 30 cases in the treatment group, treated with pediatric massage; 30 cases in the control group, treated with montelukast sodium. Observe the changes of serum IL-4, IL-13 and γ-interferon before and after treatment. Results: The total effective rate of the treatment group was 93.33%; the total effective rate of the control group was 73.33%. It was statistically significant to compare the two groups (P < 0.05). Comparing serum IL-4, IL-13, IFN-γ before and after treatment, the decreased value of IL-4 and IL-13 in the treatment group was better than that of the control group, and the increased value of IFN-γ in the treatment group was better than that of the control group. There is statistics academic significance (P < 0.05). Conclusion: Pediatric massage is better than montelukast sodium group in the treatment of cough variant asthma in the remission period.