血压变异性与脑白质病变的研究进展
Research Progress of Blood Pressure Variability and White Matter Lesions
DOI: 10.12677/ACM.2021.115293, PDF,    科研立项经费支持
作者: 张 艺, 谈 跃*：昆明医科大学第二附属医院脑血管病科，云南 昆明
关键词: 脑白质病变；血压变异性；研究进展；White Matter Lesions； Blood Pressure Variability； The Research Progress
摘要: 脑白质病变是以神经纤维脱髓鞘为主要病理改变的一种亚临床脑血管疾病，是脑小血管病的典型表现之一。脑白质病变好发于老年人，目前研究认为，脑白质病变与卒中风险增加、血管性痴呆、认知功能障碍等密切相关。高血压是脑白质病变公认的危险因素，同时血压变异性也与脑白质病变的发生密切相关，二者相关的机制目前尚未完全明确。本文对血压变异性与脑白质病变的研究进展进行综述，旨在为脑白质病变的防治提供一定依据。
Abstract: White matter lesions is a kind of subclinical cerebrovascular disease with demyelination of nerve fibers as the main pathological change, which is one of the typical manifestations of cerebral small vessel disease. White matter lesions tend to occur in the elderly. Current studies believe that white matter lesions is closely related to the increased risk of storke, vascular dementia, cognitive dysfuntion and son on. Hypertension is a recognized risk factor for white matter lesions, and blood pressure variability is also closely related to the white matter lesions. The mechanism of the correlation between the blood pressure variability and white matter lesions is not fully understand. In this paper, the research progress of blood pressure variability and white matter lesions is reviewed in order to provide some basis for the prevention and treatment of white matter lesions.
文章引用：张艺, 谈跃. 血压变异性与脑白质病变的研究进展[J]. 临床医学进展, 2021, 11(5): 2048-2054. https://doi.org/10.12677/ACM.2021.115293

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