心肌声学造影评价苓桂术甘汤颗粒剂型治疗冠心病的临床疗效

Clinical Effect of Lingguizhugan Decoction Granule in the Treatment of Coronary Heart Disease Evaluated by Myocardial Contrast Echocardiography

摘要: 目的：探讨苓桂术甘汤颗粒剂型在冠心病治疗中的疗效。方法：将60例冠心病患者分为30例对照组及30例治疗组，对照组患者予冠心病西医标准治疗；治疗组患者予冠心病西医标准治疗联合苓桂术甘汤颗粒剂型治疗，60例冠心病患者治疗前及治疗后均行心肌声学造影检查，治疗30天后比较两组治疗疗效及心肌的血流量。结果：治疗后治疗组的中医证候积分减低(P = 0.014)，心肌的血流量增高(P = 0.021)，临床治疗总有效率增高(P = 0.001)。结论：苓桂术甘汤颗粒剂型降低了冠心病患者的中医证候积分，提高心肌血流量，为临床应用苓桂术甘汤颗粒剂型治疗冠心病提供了依据。

Abstract: Objective: To investigate the effect of Lingguizhugan Decoction granule in the treatment of co-ronary heart disease. Methods: 60 patients with coronary heart disease were divided into con-trol group (n = 30) and treatment group (n = 30). Patients in the control group received stan-dard western medicine treatment for coronary heart disease, and patients in the treatment group were treated with standard treatment of western medicine combined with granule dosage form of Lingguizhugan Decoction. Myocardial contrast acoustic examination was performed in all patients before and after treatment. After 30 days of treatment, the therapeutic efficacy and myocardial blood flow were compared between the two groups. Results: After treatment, the TCM syndrome score of the treatment group decreased (P = 0.014), the myocardial blood flow increased (P = 0.021), and the total effective rate of clinical treatment increased (P = 0.001). Conclusions: Lingguizhugan Decoction granule can reduce the TCM syndrome score of patients with coronary heart disease, improve myocardial blood flow, and this study may provide basis for clinical application of Lingguizhugan Decoction granule in the treatment of coronary heart disease.