2例不同临床分型嗜酸性粒细胞性胃肠炎患者反复发作的临床特点分析
Clinical Analysis of Recurrent Episodes of Eosinophil Gastroenteritis in 2 Patients with Different Clinical Type
DOI: 10.12677/ACM.2021.115323, PDF,   
作者: 李 倩, 单体栋:青岛大学附属医院消化内科,山东 青岛;韩晓翠:青岛大学附属医院病理科,山东 青岛
关键词: 嗜酸性粒细胞性胃肠炎反复发作临床特点诊治Eosinophil Gastroenteritis Recurrent Attacks Clinical Features Diagnosis and Treatment
摘要: 嗜酸性粒细胞性胃肠炎(eosinophilic gastroenteritis, EG)是一种临床症状及内镜表现多样化、病因不十分明确的原发性嗜酸粒细胞性胃肠道疾病(EGID),不同类型的EG患者有不同的临床表现,如腹痛、腹水等,其临床表现取决于肠壁内嗜酸细胞浸润的深度,EG的年龄分布广泛,以30~50岁多见,男性多于女性。本文选取了我院2020年2~4月份接诊的2例不同临床表现及分型的EG年轻患者进行报道,患者经治疗后均短期内好转出院,后再次反复发作就诊治疗,遂结合相关的文献对不同类型EG患者的临床特点及诊治预后进行分析总结,进一步加深临床医生对此病的认识与总结,提高本病的确诊率,降低误诊率及复发率。
Abstract: Eosinophilic gastroenteritis is a primary eosinophilic gastrointestinal disease with diverse clinical symptoms and endoscopic manifestations and unclear etiology. Different types of EG patients have different clinical manifestations. The clinical manifestation depends on the depth of eosinophil infiltration in the intestinal wall. EG age distribution is widespread, with more males than females in the range of 30~50 years. In this paper, two young patients with different clinical manifestations and types of EG admitted to our hospital from February to April 2020 were selected and reported. After treatment, the patients were improved and discharged in a short period of time, and repeated attacks after discharge. Therefore, combined with the relevant literature, the clinical characteristics, diagnosis, treatment and prognosis of different types of EG patients were analyzed and summarized to further deepen the understanding and summary of the disease by clinicians, improve the diagnosis rate of the disease, and reduce the misdiagnosis rate and recurrence rate.
文章引用:李倩, 单体栋, 韩晓翠. 2例不同临床分型嗜酸性粒细胞性胃肠炎患者反复发作的临床特点分析[J]. 临床医学进展, 2021, 11(5): 2244-2250. https://doi.org/10.12677/ACM.2021.115323

参考文献

[1] Kalantar, S., et al. (1997) Dyspepsia Due to Eosinophilic Gastroenteritis. Digestive Diseases and Sciences, 42, 2327- 2332. [Google Scholar] [CrossRef
[2] Pineton de Chambrun, G., et al. (2011) Natural History of Eosinophilic Gastroenteritis. Clinical Gastroenterology and Hepatology: The Official Clinical Practice Journal of the American Gastroenterological Association, 9, 950-956.e1. [Google Scholar] [CrossRef] [PubMed]
[3] Pineton de Chambrun, G., et al. (2018) Diagnosis, Natural History and Treatment of Eosinophilic Enteritis: A Review. Current Gastroenterology Reports, 20, 37. [Google Scholar] [CrossRef] [PubMed]
[4] Mori, A., et al. (2013) Eosinophilic Gastroenteritis: Review of a Rare and Treatable Disease of the Gastrointestinal Tract. Case Reports in Gastroenterology, 7, 293-298. [Google Scholar] [CrossRef] [PubMed]
[5] Chang, J., et al. (2010) A Shift in the Clinical Spectrum of Eosinophilic Gastroenteritis toward the Mucosal Disease Type. Clinical Gastroenterology and Hepatology: The Official Clinical Practice Journal of the American Gastroenterological Association, 8, 669-675, quiz e88. [Google Scholar] [CrossRef
[6] 丰艳, 燕善军, 嗜酸性粒细胞性胃肠炎的诊断及治疗[J]. 国际消化病杂志, 2015, 35(4): 256-257+273.
[7] Alfadda, A.A. and Storr, M.A. (2011) Eosinophilic Colitis: Epidemiology, Clinical Features, and Current Management. Therapeutic Advances in Gastroenterology, 4, 301-309. [Google Scholar] [CrossRef
[8] 谢艳英, 许春进. 嗜酸性粒细胞性胃肠炎的临床诊治分析(附17例报告) [J]. 临床消化病杂志, 2019, 31(5): 294-297.
[9] Reed, C., Woosley, J. and Dellon, E. (2015) Clinical Characteristics, Treatment Outcomes, and Resource Utilization in Children and Adults with Eosinophilic Gastroenteritis. Digestive and Liver Disease. Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 47, 197-201. [Google Scholar] [CrossRef] [PubMed]
[10] 许会丽, 张连峰, 周琳. 嗜酸性粒细胞性胃肠炎98例临床特点与诊治[J]. 世界华人消化杂志, 2017, 25(36): 3224-3229.
[11] Hurrell, J.M., Genta, R.M. and Dellon, E.S. (2012) Prevalence of Esophageal Eosinophilia Varies by Climate Zone in the United States. The American Journal of Gastroenterology, 107, 698-706. [Google Scholar] [CrossRef] [PubMed]
[12] Mais, L., et al. (2014) Complicated Course of Eosinophilic Gastroenteritis: A Case Report and Literature Review. La Revue de Medecine Interne, 35, 683-685.
[13] Abassa, K.-K., et al. (2017) Diagnosis of Eosinophilic Gastroenteritis Is Easily Missed. World Journal of Gastroenterology, 23, 3556-3564. [Google Scholar] [CrossRef] [PubMed]