肾性贫血发生机制的研究现状
Research Status of the Mechanism of Renal Anemia
DOI: 10.12677/ACM.2021.115324, PDF,  被引量   
作者: 张 倩：青海大学研究生院，青海 西宁；巴应贵*：青海大学附属医院肾内科，青海 西宁
关键词: 肾性贫血；发病机制；慢性肾脏病；Renal Anemia； Pathogenesis； Chronic Kidney Disease
摘要: 贫血是慢性肾脏病(Chronic Kidney Disease, CKD)常见的并发症之一，由于各种原因导致的肾功能损害引起的红系生长因子，即促红细胞生成素(Erythropoietin, EPO)的缺乏是最主要的原因，当然还有一些毒性物质的蓄积也参与了贫血的发生。贫血的发生显著提高了患者的就诊次数及住院率，心血管事件的发生率和死亡率。有研究显示，目前在我国，有1.2亿人患有慢性肾脏疾病，预计可能还会增加。相应地贫血的发生率也会随之增加。目前对于肾性贫血治疗的达标率还不理想，因此，明确肾性贫血的机制有助于为肾性贫血的治疗提供思路。本文就肾性贫血发病机制作一综述。
Abstract: Anemia is one of the common complications of Chronic Kidney Disease (CKD). The lack of erythropoietin (EPO) caused by renal damage caused by various reasons is the main reason for this anemia. The occurrence of anemia significantly increases the number of visits and hospitalizations, the incidence and mortality of cardiovascular events. Studies have shown that there are 120 million people suffering from chronic kidney disease in my country, and it is expected to increase. Correspondingly, the incidence of anemia will also increase. At present, the rate of reaching the standard for the treatment of renal anemia is not ideal. Therefore, clarifying the mechanism of renal anemia helps to provide ideas for the treatment of renal anemia. This article summarizes the pathogenesis of renal anemia.
文章引用：张倩, 巴应贵. 肾性贫血发生机制的研究现状[J]. 临床医学进展, 2021, 11(5): 2251-2256. https://doi.org/10.12677/ACM.2021.115324

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