小肠腺癌的研究进展
Research Progress and Therapeutic Trend of Small Intestinal Neuroendocrine Neoplasms
DOI: 10.12677/ACM.2021.115343, PDF,   
作者: 李思思:昆明理工大学医学院,云南 昆明;万 苹*:昆明理工大学附属医院消化科,云南 昆明
关键词: 小肠腺癌小肠治疗Small Bowel Adenocarcinoma Small Intestine Treatment
摘要: 小肠腺癌是一种十分罕见的肿瘤,确诊往往即已发生转移,不能完全手术切除。如今肿瘤研究已经进入精准医疗的范畴,如何采用多学科方法,结合不同的治疗方案有效治疗小肠腺癌仍是目前的疑难问题。本篇综述尝试通过对以往的研究进行总结和更新的概述,以探寻未来的研究方向。
Abstract: In recent years, the incidence of small bowel adenocarcinoma (SBA) is group of rare tumors. The tumors often diagnosed with metastases and cannot be completely removed. Nowadays, tumor investigations have entered the category of precision medicine. How to treat SBA effectively with multidisciplinary approach and different treatment schemes is still a difficult problem at present. This review attempts to summarize and update previous studies to explore future research directions of SBA.
文章引用:李思思, 万苹. 小肠腺癌的研究进展[J]. 临床医学进展, 2021, 11(5): 2387-2391. https://doi.org/10.12677/ACM.2021.115343

参考文献

[1] Siegel, R.L., Miller, K.D. and Jemal, A. (2016) Cancer Statistics, 2016. CA: A Cancer Journal for Clinicians, 66, 7-30. [Google Scholar] [CrossRef] [PubMed]
[2] Schottenfeld, D., Beebe-Dimmer, J.L. and Vigneau, F.D. (2009) The Epidemiology and Pathogenesis of Neoplasia in the Small Intestine. Annals of Epidemiology, 19, 58-69. [Google Scholar] [CrossRef] [PubMed]
[3] Aparicio, T., Zaanan, A., Svrcek, M., et al. (2014) Small Bowel Adenocarcinoma: Epidemiology, Risk Factors, Diagnosis and Treatment. Digestive and Liver Disease, 46, 97-104. [Google Scholar] [CrossRef] [PubMed]
[4] Agrawal, S., McCarron, E.C., Gibbs, J.F., et al. (2007) Surgical Management and Outcome in Primary Adenocarcinoma of the Small Bowel. Annals of Surgical Oncology, 14, 2263-2269. [Google Scholar] [CrossRef] [PubMed]
[5] Bennett, C.M., Coleman, H.G., Veal, P.G., et al. (2015) Lifestyle Factors and Small Intestine Adenocarcinoma Risk: A Systematic Review and Meta-Analysis. Cancer Epidemiology, 39, 265-273. [Google Scholar] [CrossRef] [PubMed]
[6] Boffetta, P., Hazelton, W.D., Chen, Y., et al. (2012) Body Mass, Tobacco Smoking, Alcohol Drinking and Risk of Cancer of the Small Intestine—A Pooled Analysis of over 500,000 Subjects in the Asia Cohort Consortium. Annals of Oncology, 23, 1894-1898. [Google Scholar] [CrossRef] [PubMed]
[7] Vasen, H.F., Bülow, S., Myrhøj, T., et al. (1997) Decision Analysis in the Management of Duodenal Adenomatosis in Familial Adenomatous Polyposis. Gut, 40, 716-719. [Google Scholar] [CrossRef] [PubMed]
[8] Dabaja, B.S., Suki, D., Pro, B., et al. (2004) Adenocarcinoma of the Small Bowel: Presentation, Prognostic Factors, and Outcome of 217 Patients. Cancer, 101, 518-526. [Google Scholar] [CrossRef] [PubMed]
[9] Canavan, C., Abrams, K.R. and Mayberry, J. (2006) Meta-Analysis: Colorectal and Small Bowel Cancer Risk in Patients with Crohn’s Disease. Alimentary Pharmacology & Therapeutics, 23, 1097-1104. [Google Scholar] [CrossRef] [PubMed]
[10] Palascak-Juif, V., Bouvier, A.M., Cosnes, J., et al. (2005) Small Bowel Adenocarcinoma in Patients with Crohn’s Disease Compared with Small Bowel Adenocarcinoma de Novo. Inflammatory Bowel Diseases, 11, 828-832. [Google Scholar] [CrossRef] [PubMed]
[11] Lim, W., Hearle, N., Shah, B., et al. (2003) Further Observations on LKB1/STK11 Status and Cancer Risk in Peutz- Jeghers Syndrome. British Journal of Cancer, 89, 308-313. [Google Scholar] [CrossRef] [PubMed]
[12] Beggs, A.D., Latchford, A.R., Vasen, H.F., et al. (2010) Peutz-Jeghers Syndrome: A Systematic Review and Recommendations for Management. Gut, 59, 975-986. [Google Scholar] [CrossRef] [PubMed]
[13] Giardiello, F.M., Brensinger, J.D., Tersmette, A.C., et al. (2000) Very High Risk of Cancer in Familial Peutz-Jeghers Syndrome. Gastroenterology, 119, 1447-1453. [Google Scholar] [CrossRef] [PubMed]
[14] Koornstra, J.J., Kleibeuker, J.H. and Vasen, H.F. (2008) Small-Bowel Cancer in Lynch Syndrome: Is It Time for Surveillance? The Lancet Oncology, 9, 901-905. [Google Scholar] [CrossRef
[15] Cazzato, I.A., Cammarota, G., Nista, E.C., et al. (2007) Diagnostic and Therapeutic Impact of Double-Balloon Enteroscopy (DBE) in a Series of 100 Patients with Suspected Small Bowel Diseases. Digestive and Liver Disease, 39, 483-487. [Google Scholar] [CrossRef] [PubMed]
[16] Chen, W.G., Shan, G.D., Zhang, H., et al. (2016) Double-Balloon Enteroscopy in Small Bowel Diseases: Eight Years Single-Center Experience in China. Medicine (Baltimore), 95, e5104. [Google Scholar] [CrossRef
[17] Paski, S.C. and Semrad, C.E. (2009) Small Bowel Tumors. Gastrointestinal Endoscopy Clinics of North America, 19, 461-479. [Google Scholar] [CrossRef] [PubMed]
[18] Ren, M., Yuan, G., Zhu, S.L., et al. (2009) Evaluation of Capsule Endoscopy in the Diagnosis of Small Bowel Disease. Chinese Journal of Gastrointestinal Surgery, 12, 163-166.
[19] Li, X., Gui, Y., Shen, F., et al. (2018) The Application Value of Capsule Endoscopy in Diagnosing Small Intestinal Carcinoma. Journal of Cancer Research and Therapeutics, 14, 57-60. [Google Scholar] [CrossRef
[20] Paulsen, S.R., Huprich, J.E., Fletcher, J.G., et al. (2006) CT Enterography as a Diagnostic Tool in Evaluating Small Bowel Disorders: Review of Clinical Experience with over 700 Cases. RadioGraphics, 26, 641-657. [Google Scholar] [CrossRef] [PubMed]
[21] 石爱军, 包忠英. 胶囊内镜联合小肠CT造影在小肠疾病中的诊断价值[J]. 影像研究与医学应用, 2017, 1(4): 82-84.
[22] Kamaoui, I., De-Luca, V., Ficarelli, S., et al. (2010) Value of CT Enteroclysis in Suspected Small-Bowel Carcinoid Tumors. American Journal of Roentgenology, 194, 629-633. [Google Scholar] [CrossRef
[23] Tran, T.B., Qadan, M., Dua, M.M., et al. (2015) Prognostic Relevance of Lymph Node Ratio and Total Lymph Node Count for Small Bowel Adenocarcinoma. Surgery, 158, 486-493. [Google Scholar] [CrossRef] [PubMed]
[24] Li, X., Ying, H., Cheng, Y., et al. (2019) Clinicopathological Features and Treatment Outcomes of Metastatic or Locally Unresectable Small Bowel Adenocarcinoma. Journal of B.U.ON., 24, 2539-2545.
[25] Rovers, K.P., de Bree, E., Yonemura, Y., et al. (2017) Treatment of Peritoneal Metastases from Small Bowel Adenocarcinoma. International Journal of Hyperthermia, 33, 571-578. [Google Scholar] [CrossRef] [PubMed]
[26] Giuffrida, P., Arpa, G., Grillo, F., et al. (2020) PD-L1 in Small Bowel Adenocarcinoma Is Associated with Etiology and Tumor-Infiltrating Lymphocytes, in Addition to Microsatellite Instability. Modern Pathology, 33, 1398-1409. [Google Scholar] [CrossRef] [PubMed]
[27] Overman, M.J., Adam, L., Raghav, K., et al. (2018) Phase II Study of Nab-Paclitaxel Inrefractory Small Bowel Adenocarcinoma and CpG Island Methylatorphenotype (CIMP)-High Colorectal Cancer. Annals of Oncology, 29, 139-144. [Google Scholar] [CrossRef] [PubMed]