早期气道开放对神经ICU镇静患者的临床影响分析

Clinical Effect Analysis of Early Airway Opening on Neurological ICU Sedation Patients

摘要: 目的：分析在应用镇静治疗的神经ICU患者中早期施行气道开放对患者临床的影响。方法：回顾性分析52例神经ICU镇静患者的临床资料，根据开放气道情况将患者分为早期气道开放组(试验组)与早期气道未开放组(对照组)，比较两组患者新发肺炎率、机械通气时间、ICU住院时间、不良反应发生情况。结果：试验组机械通气使用时间、ICU住院时间均低于对照组(P < 0.05)；两组患者不良反应比较，试验组新发肺炎、呼吸衰竭、谵妄发生情况与对照组比较差异有统计学意义(P < 0.05)，低血压、心动过缓两组比较差异无统计学意义(P > 0.05)。结论：在神经ICU镇痛患者中早期施行气道开放可以缩短患者的住院时间，降低患者住院期间肺炎发生可能，减少机械通气的使用时间，使得患者有临床获益。

Abstract: Objective: To analyze the clinical effect of early airway opening in neurological ICU patients treated with sedation. Method: The clinical data of 52 patients with neurological ICU sedation were retrospectively analyzed. According to the condition of open airway, the patients were divided into early airway opening group (experimental group) and early airway non-opening group (control group). The incidence of pneumonia, the length of stay in ICU, the mechanical ventilation time and the incidence of adverse reactions of the two groups were compared. Results: The duration of mechanical ventilation and ICU hospitalization in experimental group were lower than those in control group (P < 0.05). There were statistically significant differences in the incidence of new pneumonia, respiratory failure and delirium between the experimental group and the control group (P < 0.05), while there were no statistically significant differences in hypotension and bradycardia between the two groups (P > 0.05). Conclusion: Early implementation of airway opening in neuro ICU patients with analgesia can shorten the length of hospital stay, reduce the possibility of pneumonia during hospitalization, and reduce the use time of mechanical ventilation, so that patients have clinical benefits.