慢性阻塞性肺疾病发病机制研究进展
Progress in the Pathogenesis of Chronic Obstructive Pulmonary Disease (COPD)
摘要: 慢性阻塞性肺疾病(COPD)是一种世界范围内的常见病、多发病，且在青中年人群中的发病率呈上升趋势，造成个人生活质量下降及社会重要的经济负担，从而引起人们的广泛关注。关于COPD的发病机制研究目前尚未明确阐述，研究其发病机制及根本治疗方法对COPD患者至关重要。本文就慢性阻塞性肺疾病的炎症、氧化应激、蛋白酶与抗蛋白失衡及细胞衰老与凋亡方面作一综述。
Abstract: Chronic obstructive pulmonary disease (COPD) is a common and frequently occurring disease worldwide, and its incidence in young and middle-aged populations is on the rise. It causes a decline in the quality of life of individuals and an important economic burden to society, thus causing people’s wide attention. Research on the pathogenesis of COPD has not yet been clearly elucidated, and the study of its pathogenesis and fundamental treatment methods is very important for COPD patients. This article reviews the aspects of chronic obstructive pulmonary disease inflammation, oxidative stress, protease and anti-protein imbalance, cell senescence and apoptosis.
文章引用：张曼, 刘雅, 孙伟民. 慢性阻塞性肺疾病发病机制研究进展[J]. 临床医学进展, 2021, 11(6): 2685-2688. https://doi.org/10.12677/ACM.2021.116388

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