肝细胞肝癌代谢异常相关问题的研究现状及展望

Research Status and Prospect of Metabolic Abnormalities in Hepatocellular Carcinoma

摘要: 肝细胞肝癌(下简称“肝癌”)作为目前全球第四大死因，诊断与治疗都尚未达到一个理想的水平。肝脏作为人体最大也是最重要的代谢器官之一，在人体糖质、脂肪酸、维生素等人体常见元素的代谢中起到重要的作用。同时，代谢异常相关疾病发病率逐渐上升，其中不少疾病已经成为肝脏相关疾病的高危因素、起因等。代谢相关疾病与肝癌的相关研究已多见报道。本文从脂肪酸代谢、糖质代谢以及维生素代谢三个角度，对肝癌与代谢异常相关问题做简要的阐述。

Abstract: As the fourth leading cause of death in the world, liver cancer, of which hepatocellular carcinoma (HCC) is the dominant variety, has not yet reached an ideal level of diagnosis and treatment. As one of the largest and most important metabolic organs of the human body, the liver plays an important role in the metabolism of glucose, lipids, proteins, vitamins and hormones. At the same time, the incidence of metabolic abnormalities-related diseases is gradually increasing. Many of them have become high-risk factors and causes of liver diseases. Researches on metabolism-related diseases and liver cancer have been reported frequently. This article will briefly explain the problems related to liver cancer and abnormal metabolism from the perspectives of lipid metabolism, glucose metabolism and vitamin metabolism.