妊娠合并系统性红斑狼疮伴肺动脉高压一例并文献复习
Pregnancy Complicated with Systemic Lupus Erythematosus with Pulmonary Hypertension: A Case Report and Literature Review
DOI: 10.12677/ACM.2021.116398, PDF,   
作者: 张 冉:青岛大学,山东 青岛;徐 琳, 王 宁:青岛大学附属医院,山东 青岛
关键词: 妊娠系统性红斑狼疮肺动脉高压Pregnancy Systemic Lupus Erythematosus Pulmonary Hypertension
摘要: 系统性红斑狼疮(Systemic lupus erythematosus, SLE)是一种多发于青年女性的多器官损伤的慢性自身免疫性疾病,肺动脉高压(Pulmonary hypertension, PAH)是系统性红斑狼疮少见但严重的并发症。现报道一例妊娠合并系统性红斑狼疮伴肺动脉高压的患者,孕期规律治疗,经多学科联合诊治,于孕37周 + 3天,行硬膜外麻醉下剖宫产顺利分娩,术后患者病情控制良好。
Abstract: Systemic lupus erythematosus is a chronic autoimmune disease with multiple organ damage in young women. Pulmonary hypertension is a rare but serious complication of systemic lupus erythematosus. It is reported that a case of pregnancy complicated with systemic lupus erythematosus with pulmonary hypertension was treated regularly during pregnancy. After multidisciplinary diagnosis and treatment, she delivered successfully by cesarean section under epidural anesthesia at 37 weeks and 3 days of pregnancy. The patient’s condition was well controlled after the operation.
文章引用:张冉, 徐琳, 王宁. 妊娠合并系统性红斑狼疮伴肺动脉高压一例并文献复习[J]. 临床医学进展, 2021, 11(6): 2753-2756. https://doi.org/10.12677/ACM.2021.116398

参考文献

[1] Ateka-Barrutia, O. and Khamashta, M. (2013) The Challenge of Pregnancy for Patients with SLE. Lupus, 22, 1295-1308. [Google Scholar] [CrossRef] [PubMed]
[2] 中华医学会呼吸病学分会肺栓塞与肺血管病学组, 中国医师协会呼吸医师分会肺栓塞与肺血管病工作委员会, 全国肺栓塞与肺血管病防治协作组, 等. 中国肺动脉高压诊断与治疗指南(2021版) [J]. 中华医学杂志, 2021, 101(1): 11-51.
[3] Fanouriakis, A., Tziolos, N., Bertsias, G., et al. (2021) Update on the Diagnosis and Management of Systemic Lupus Erythematosus. Annals of the Rheumatic Diseases, 80, 14-25. [Google Scholar] [CrossRef] [PubMed]
[4] Chow, S.L., Chandran, V., Fazelzad, R., et al. (2012) Prognostic Factors for Survival in Systemic Lupus Erythematosus Associated Pulmonary Hypertension. Lupus, 21, 353-364. [Google Scholar] [CrossRef] [PubMed]
[5] Streit, M., Speich, R., Fischler, M., et al. (2009) Successful Pregnancy in Pulmonary Arterial Hypertension Associated with Systemic Lupus Erythematosus: A Case Report. Journal of Medical Case Reports, 3, 7255. [Google Scholar] [CrossRef] [PubMed]
[6] 郭晓玥, 邵珲, 赵扬玉. 系统性红斑狼疮患者孕期并发肺动脉高压1例[J]. 北京大学学报(医学版), 2018, 50(5): 928-931.
[7] Nahal, S.K., Selmi, C. and Gershwin, M.E. (2018) Safety Issues and Recommendations for Successful Pregnancy Outcome in Systemic Lupus Erythematosus. Journal of Autoimmunity, 93, 16-23. [Google Scholar] [CrossRef] [PubMed]
[8] 国家风湿病数据中心, 中国系统性红斑狼疮研究协作组. 中国成人系统性红斑狼疮相关肺动脉高压诊治共识[J]. 中国实用内科杂志, 2015, 35(2): 129-135, 138.
[9] 郭松, 张建平. 妊娠合并系统性红斑狼疮活动期的管理[J]. 中华产科急救电子杂志, 2017, 6(1): 14-18.