原发性子宫弥漫性大B细胞淋巴瘤1例并文献复习
Primary Uterine Diffuse Large B-Cell Lymphoma: A Case Report and Literature Review
DOI: 10.12677/ACM.2021.117434, PDF,   
作者: 隋 磊, 纪晓宇, 姚 勤:青岛大学附属医院妇科,山东 青岛
关键词: 子宫淋巴瘤原发性结外淋巴瘤治疗Uterus Lymphoma Primary Extranodal Lymphoma Treatment
摘要: 目的:探讨原发性子宫弥漫性大B细胞淋巴瘤的临床表现及诊治要点。方法:对1例原发性子宫弥漫性大B细胞淋巴瘤的患者进行回顾性分析并文献复习。结果:本例患者为69岁女性,以绝经后阴道流血为初期症状,入院行择期手术治疗,最终被诊断为原发性子宫弥漫性大B细胞淋巴瘤。结论:原发性子宫淋巴瘤是一种极为罕见的疾病,临床表现无特异性。治疗方面现以根治性手术联合化疗为主。
Abstract: Objective: To investigate the clinical manifestations, diagnosis and treatment of primary uterine diffuse large B-cell lymphoma. Methods: A case of primary uterine diffuse large B-cell lymphoma was analyzed retrospectively and the literature was reviewed. Results: The patient was a 69-year-old woman with postmenopausal vaginal bleeding as the initial symptom, who was admitted to hospital for elective surgery, and was finally diagnosed as primary uterine diffuse large B-cell lymphoma. Conclusion: Primary uterine lymphoma is a rare disease with no specific clinical manifestations. Radical surgery combined with chemotherapy is the main treatment.
文章引用:隋磊, 纪晓宇, 姚勤. 原发性子宫弥漫性大B细胞淋巴瘤1例并文献复习[J]. 临床医学进展, 2021, 11(7): 2992-2995. https://doi.org/10.12677/ACM.2021.117434

参考文献

[1] Lagoo, A.S. and Robboy, S.J. (2006) Lymphoma of the Female Genital Tract: Current Status. International Journal of Gynecological Pathology, 25, 1-21. [Google Scholar] [CrossRef] [PubMed]
[2] Cao, X.X., Li, J., Cai, H., Zhang, W., Duan, M.H. and Zhou, D.B. (2017) Patients with Primary Breast and Primary Female Genital Tract Diffuse Large B Cell Lymphoma Have a High Frequency of MYD88 and CD79B Mutations. Annals of Hematology, 96, 1867-1871. [Google Scholar] [CrossRef] [PubMed]
[3] Paes, F.M., Kalkanis, D.G., Sideras, P.A. and Serafini, A.N. (2010) FDG PET/CT of Extranodal Involvement in Non-Hodgkin Lymphoma and Hodgkin Disease. RadioGraphics, 30, 269-291. [Google Scholar] [CrossRef] [PubMed]
[4] Nasioudis, D., Kampaktsis, P.N., Frey, M., Witkin, S.S. and Holcomb, K. (2017) Primary Lymphoma of the Female Genital Tract: An Analysis of 697 Cases. Gynecologic Oncology, 145, 305-309. [Google Scholar] [CrossRef] [PubMed]
[5] Ishii, Y., Fujisawa, S., Ando, T., Suzuki, T., Ishiyama, Y., Kishimoto, K., Hattori, Y., Nakajima, Y., Miyazaki, T., Takasaki, H., Matsumoto, K., Koharazawa, H., Taguchi, J., Fujimaki, K., Sakai, R. and Nakajima, H. (2018) Primary Uterine Lymphoma: The Yokohama Cooperative Study Group for Hematology (YACHT) Study. Asia Pacific Journal of Clinical Oncology, 14, e455-e459. [Google Scholar] [CrossRef] [PubMed]
[6] Saleh, G.A., Alghandour, R., Rashad, E.Y., Tawfik, A.M. and Elmokadem, A.H. (2021) The Adjunctive Value of Diffusion Weighted Imaging in Diagnosis and Follow up of Uterovaginal Diffuse B-Cell Lymphoma: A Case Report and Literature Review. Current Medical Imaging. [Google Scholar] [CrossRef] [PubMed]
[7] Sugimoto, M., Koyama, K., Ichimura, T., Shimono, T., Hashiguchi, Y. and Miki, Y. (2019) Comparison of MR Imaging Features of Uterine Neuroendocrine Carcinoma and Uterine Malignant Lymphoma. Abdominal Radiology, 44, 3377-3387. [Google Scholar] [CrossRef] [PubMed]
[8] Fox, H. and More, J.R. (1965) Primary Malignant Lymphoma of the Uterus. Journal of Clinical Pathology, 18, 723-728. [Google Scholar] [CrossRef] [PubMed]
[9] Cubo, A.M., Soto, Z.M., Cruz, M., Doyague, M.J., Sancho, V., Fraino, A., Blanco, Ó., Puig, N., Alcoceba, M., González, M. and Sayagués, J.M. (2017) Primary Diffuse Large B Cell Lymphoma of the Uterine Cervix Successfully Treated by Combined Chemotherapy Alone: A Case Report. Medicine (Baltimore), 96, e6846. [Google Scholar] [CrossRef] [PubMed]
[10] Goda, J.S., Gaikwad, U., Narayan, A., Kurkure, D., Yadav, S., Khanna, N., Jain, H., Bagal, B., Epari, S., Singh, P., Sengar, M. and Laskar, S. (2020) Primary Diffuse Large B Cell Lymphoma of Uterine Cervix: Treatment Outcomes of a Rare Entity with Literature Review. Cancer Reports (Hoboken), 3, e1264. [Google Scholar] [CrossRef] [PubMed]