冠状动脉造影联合FFR在冠心病介入治疗中的应用分析

Analysis of the Application of Coronary Angiography Combined with FFR in Interventional Therapy of Coronary Heart Disease

摘要: 目的：评估冠状动脉造影和心肌血流储备分数(FFR)结合使用于冠心病患者介入治疗过程中的运用价值。方法：对2017年05月~2019年06月本医院纳入且拟行临床介入治疗的60例冠心病患者实施这次指标统计分析，依据病例入院日期单双号实施分组干预，入院日期最后一位数为单号的30例患者归入参比组调查研究资料，本组冠状动脉狭窄病变处实行经皮冠状动脉介入治疗常规药物洗脱支架置入干预，入院日期最后一位数为双号的30例患者归入实验组调查研究资料，本组冠状动脉狭窄病变处实行压力导丝开展心肌血流储备分数检测，于心肌血流储备分数检测值低于等于0.80的冠状动脉狭窄病变处实行药物洗脱支架置入干预，于术后心肌血流储备分数检测值低于等于0.80的冠状动脉狭窄病变处实行支架内球囊后扩张干预，对比不同组别冠状动脉狭窄病变处数、住院治疗花费、冠状动脉支架置入个数、再次出现心肌梗死例数、再次血运重建例数、再次出现心绞痛例数、术后六个月内死亡情况。结果：实验组冠状动脉狭窄病变处数和参比组评估数据值对比，数值检验结果之间差别并不显著(P > 0.05)，实验组住院治疗花费、冠状动脉支架置入个数比较参比组评估数据值下降明显，数值检验结果之间差别十分显著(P < 0.05)；实验组再次出现心肌梗死例数、再次血运重建例数、再次出现心绞痛例数和参比组评估数据值对比，数值检验结果之间差别并不显著(P > 0.05)；各组术后六个月内都未出现死亡情况。结论：在冠心病患者介入治疗过程中采用冠状动脉造影和心肌血流储备分数(FFR)结合展示出良好效果，体现重要运用价值和推广优势所在。

Abstract: Objective: To evaluate the value of coronary angiography combined with Fractional Flow Reserve (FFR) in interventional therapy of patients with coronary heart disease. Methods: From May 2017 to June 2019, 60 patients with Coronary Heart Disease (CHD) who were included in our hospital and planned to receive clinical interventional therapy were given statistical scores of this index. Based on cases of admission date, the implementation of group intervention, admission date the final figures for the number of 30 patients were classified as reference data from field investigation and research, in this group, the coronary artery stenosis lesions were treated with percutaneous coronary intervention, routine drug-eluting stent placement intervention. The 30 patients whose last digit of admission date was double number were included in the experimental group’s investigation data. The coronary artery stenosis lesions in this group were treated with pressure guest-wire to detect myocardial blood flow reserve score. The intervention of drug-eluting stent placement was carried out in the coronary artery stenosis lesions with the myocardial blood flow reserve score lower than or equal to 0.80, and the intervention of stent balloon dilation was carried out in the coronary artery stenosis lesions with the myocardial blood flow reserve score lower than or equal to 0.80, compare different groups of coronary artery stenosis diseased region number, hospitalization costs, number of coronary artery stent implantation, myocardial infection cases again and again revascularization occurring within six months, again angina pectoris cases and postoperative deaths. Results: The comparison of the number of coronary artery stenosis lesions in the experimental group and the evaluation data values in the reference group showed no significant difference between the numerical test results (P > 0.05), the cost of hospitalization and the number of coronary stent implantation in the experimental group decreased significantly compared with the reference group, and the difference between the numerical test results was significant (P < 0.05); the number of myocardial infarctions again, the number of revascularization, the number of angina again, and the comparison of the evaluation data values of the reference group showed no significant difference between the numerical test results (P > 0.05); there was no death six months after an operation in each group. Conclusion: The combination of coronary angiography and Fractional Flow Reserve (FFR) in the interventional therapy of coronary heart disease patients shows good results, which reflects the important application value and promotion advantages.