保留大隐静脉分支的Y形桥在冠状动脉旁路移植术中的应用价值研究
Application Value of Y-Shaped Bridge with Great Saphenous Vein Branch Preserved in Coronary Artery Bypass Grafting
DOI: 10.12677/ACM.2021.117440, PDF,   
作者: 路 程:青岛大学医学部,山东 青岛;于仁斌, 杨苏民*:青岛大学附属医院心血管外科,山东 青岛
关键词: 冠状动脉旁路移植术大隐静脉血流量搏动指数Coronary Artery Bypass Grafting Great Saphenous Vein Blood Flow Pulsatility Index
摘要: 目的:探讨保留大隐静脉分支做天然Y形桥在冠状动脉旁路移植术中的应用价值。方法:选取研究对象为2017年12月至2019年12月在青岛大学附属医院行非体外循环下冠状动脉旁路移植术的患者100例。其中50例患者术中保留大隐静脉分支做桥血管记为观察组,其余50例患者仅保留大隐静脉主干做序贯桥记为对照组。对比两组患者术中静脉桥各吻合口血流量、搏动指数(PI)和大隐静脉使用长度,以及术后1个月、6个月、1年的左心室射血分数(LVEF)。结果:相较于对照组,观察组术中静脉桥血流量更高,PI也更优,实际应用的静脉长度也较短。两组患者术后短期(术后1个月、6个月)心功能并无明显差异,术后中期(术后1年)观察组的左心室射血分数(LVEF)明显升高。结论:在冠状动脉旁路移植术中保留大隐静脉的分支做天然Y形桥较传统单支序贯桥能提供更好的血流,提高术后左心功能,节约静脉桥长度。
Abstract: Objective: Explore the value of preserving the great saphenous vein branch as a natural Y-shaped bridge in coronary artery bypass grafting. Methods: 100 patients who underwent off-pump coronary artery bypass grafting in the Affiliated Hospital of Qingdao University from December 2017 to December 2019 were selected as the research objects. Among them, 50 patients kept the branches of great saphenous vein as bridging vessels during operation as the observation group, and the remaining 50 patients only kept the trunk of great saphenous vein as sequential bridging vessels as the control group. The blood flow, pulsatility index (PI), the length of saphenous vein, left ventricular ejection fraction (LVEF). Results: Compared with the control group, the blood flow of vein bridge in the observation group was higher, the PI was better, and the length of vein used in practice was shorter. There was no significant difference in short-term (1 month, 6 months) postoperative cardiac function between the two groups. The left ventricular ejection fraction (LVEF) in the observation group was significantly increased in the middle term (1 year) after operation. Conclusion: In coronary artery bypass grafting, preserving the saphenous vein branch as a natural Y-shaped bridge can provide better blood flow, improve postoperative left ventricular function and save the length of vein bridge.
文章引用:路程, 于仁斌, 杨苏民. 保留大隐静脉分支的Y形桥在冠状动脉旁路移植术中的应用价值研究[J]. 临床医学进展, 2021, 11(7): 3027-3032. https://doi.org/10.12677/ACM.2021.117440

参考文献

[1] 张旭, 艾斯卡尔·沙比提. 冠状动脉旁路移植术的现状与展望[J]. 中国循证心血管医学杂志, 2017, 9(2): 254-256.
[2] Haltky, M.A., Boothroyd, D.B., Bravata, D.M., et al. (2009) Coronary Artery Bypass Surgery Compared with Percutaneous Coronary Interventions for Muhivessel Disease: A Collaborative Analysis of Individual Patient Data from Ten Randomised Trials. Lancet, 373, 1190-1197. [Google Scholar] [CrossRef
[3] Lamy, A., Tong, W., Devereaux, P.J., et al. (2014) The Cost Implications of Off-Pump versus On-Pump Coronary Artery Bypass Graft Surgery at One Year. The Annals of Thoracic Surgery, 98, 1620-1625. [Google Scholar] [CrossRef] [PubMed]
[4] 何平海. 非体外循环冠状动脉旁路移植术大隐静脉单支吻合同序贯吻合通畅率的比较研究[D]: [硕士学位论文]. 合肥: 安徽医科大学, 2018.
[5] 宋跃. 308例老年冠心病患者非体外循环冠状动脉搭桥术临床效果分析[J]. 中国动脉硬化杂志, 2014, 22(1): 72-74.
[6] 王圣, 程兆云, 赵子牛, 等. 冠状动脉分流器在非体外循环冠状动脉搭桥术中的应用[J]. 中国动脉硬化杂志, 2016, 24(10): 1035-1038.
[7] 陈曦, 郑辉, 谢波, 等. 三种风险度评分在非体外循环下冠脉搭桥术后急性肾损伤预测中的应用和比较[J]. 中国心血管病研究, 2017, 15(3): 231-236.
[8] Gaudino, M., Benedetto, U., Fremes, S., et al. (2018) Radial-Artery or Saphenous-Vein Grafts in Coronary-Artery Bypass Surgery. The New England Journal of Medicine, 378, 2069-2077. [Google Scholar] [CrossRef
[9] Klima, U., Elsebay, A.A., Gantri, M.R., et al. (2014) Computerized Tomographic Angiography in Patients Having eSVS Mesh® Supported Coronary Saphenous Vein Grafts: Intermediate Term Results. Journal of Cardiothoracic Surgery, 9, Article No. 126. [Google Scholar] [CrossRef] [PubMed]
[10] 田美策, 王现强. 冠状动脉旁路移植术后静脉桥的衰败机制与通畅率改进措施的进展[J]. 中国循环杂志, 2020, 35(1): 98-101.
[11] Raza, S., Blackstone, E.H., Bakaeen, F.G., et al. (2019) Long-Term Patency of Individual Segments of Different Internal Thoracic Artery Graft Configurations. The Annals of Thoracic Surgery, 107, 740-746. [Google Scholar] [CrossRef] [PubMed]
[12] Lee, S.H., Chung, C.H., Jung, S.H., et al. (2012) Midterm Results of Beating Heart Coronary Bypass Surgery for Non-Left Internal Thoracic Artery Anastomosis According to Grafting Design and Implications of Intraoperative Flow Characteristics on Graft Patency. The Thoracic and Cardiovascular Surgeon, 60, 438-445. [Google Scholar] [CrossRef] [PubMed]
[13] Takazawa, A., Nakajima, H., Iguchi, A., et al. (2015) Impacts of Intraoperative Flow on Graft Patency of Sequential and Individual Saphenous Vein Grafts. Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery, 10, 85-89. [Google Scholar] [CrossRef] [PubMed]
[14] 任培军, 程兆云, 赵子牛, 等. 不同手术策略对冠状动脉搭桥术后桥血管病变的影响[J]. 中国心血管病研究, 2017, 15(11): 981-984.