慢性阻塞性肺疾病氧化应激及对动脉粥样硬化影响的研究进展
Research Progress of Oxidative Stress in Chronic Obstructive Pulmonary Disease and Its Effect on Atherosclerosis
DOI: 10.12677/ACM.2021.117446, PDF,   
作者: 杨发菊：青海大学研究生院，青海 西宁；华 毛：青海大学附属医院呼吸内科，青海 西宁
关键词: 慢性阻塞性肺疾病；氧化应激；动脉粥样硬化；Chronic Obstructive Pulmonary Disease； Oxidative Stress； Atherosclerosis
摘要: 气道氧化应激是影响慢性阻塞性肺疾病(chronic obstructive pulmonary disease, COPD)早期不断发生及持续进展的重要因素。COPD患者可因冷空气刺激、感染等诱因导致病情反复加重，进而引起心衰等心血管疾病(CVD)的发生。动脉粥样硬化是许多CVD发生最早的病理学基本特征，目前它已逐渐发展成为COPD合并CVD临床研究的新热点。氧化应激对动脉粥样硬化的疾病进展具有重要影响。
Abstract: Airway oxidative stress is an important factor affecting the continuous occurrence and progression of chronic obstructive pulmonary disease (COPD). Chronic obstructive pulmonary disease (COPD) patients can be repeatedly aggravated due to cold air stimulation, infection and other incentives, and then lead to heart failure and other cardiovascular diseases (CVD). Atherosclerosis is the earliest pathological feature of many CVD, and it has gradually become a new hot spot in the clinical research of COPD combined with CVD. Oxidative stress plays an important role in the progression of atherosclerosis.
文章引用：杨发菊, 华毛. 慢性阻塞性肺疾病氧化应激及对动脉粥样硬化影响的研究进展[J]. 临床医学进展, 2021, 11(7): 3076-3082. https://doi.org/10.12677/ACM.2021.117446

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