碘伏原液冲洗对髋关节置换术后感染率影响的回顾性研究

A Retrospective Study of the Effect of Iodophor Flushing on the Infection Rate after Hip Arthroplasty

摘要: 目的：观察碘伏原液冲洗对髋关节置换术后感染率的影响作用。方法：选取济宁市第一人民医院骨关节外科2018年1月至2020年1月住院的因“股骨头坏死”行髋关节置换术的患者作为研究对象，其中碘伏原液冲洗组(B组) 30例，生理盐水冲洗组(A组) 30例，对其进行回顾性研究，对比两组术后第1天、第3天及第5天血中的白细胞计数、中性粒细胞计数、中性粒细胞百分比、血沉、C-反应蛋白及体温变化，随访1年，对比两组术后感染概率情况。结果：想对比于生理盐水冲洗组，髋关节置换术中进行碘伏原液冲洗在术后第1天、第3天及第5天明显地降低了患者血中的白细胞计数、中性粒细胞计数、中性粒细胞百分比、血沉及C-反应蛋白，患者术后第1天、第3天及第5天体温也低于A组，随访1年，B组的术后感染率较A组明显地降低。结论：髋关节置换术中进行碘伏原液冲洗，将有效地降低术后炎症指标的表达变化，减少术后体温升高情况，降低术后感染率，有助于提高患者术后满意度，减少患者住院时间，减少患者花费及术后翻修情况发生，具有良好的社会及经济效益，值得推广及应用。

Abstract: Objective: To observe the effect of washing with iodophor stock solution on the infection rate after hip arthroplasty. Methods: Selected patients who underwent hip arthroplasty due to “femoral head necrosis” in the Department of Orthopedics and Joint Surgery of Jining First People’s Hospital from January 2018 to January 2020 were selected as the research objects, including the iodophor wash group (group B) 30 cases, 30 cases in the normal saline flushing group (group A). The blood white blood cell count, neutrophil count, neutrophil percentage, erythrocyte sedimentation rate, C-reactive protein and body temperature were compared between the two groups on the 1, 3 and 5 days after operation. Follow-up for 1 year, the postoperative infection probability between the two groups was compared. Results: Compared with the normal saline flushing group, the flushing with iodophor stock solution during hip replacement surgery significantly reduced the white blood cell count, neutrophil count, neutrophil percentage, erythrocyte sedimentation rate and C-reactive proteinin the patient’s blood on the 1, 3 and 5 days after surgery, and the patient’s body temperature on the 1, 3 and 5 days after surgery was also lower than that of group A. Follow-up for 1 year, the postoperative infection rate of group B was more obvious lower than that of group A. Conclusion: Washing with iodophor stock solution during hip arthroplasty will effectively reduce the expression changes of postoperative inflammation indicators, reduce postoperative body temperature rise, and reduce postoperative infection rate. It is helpful to improve the satisfaction of patients after surgery, reduce the length of hospital stay, reduce the cost of patients and the occurrence of postoperative renovations. It has good social and economic benefits and is worthy of promotion and application.