杏仁核在情绪加工中的特异性与非特异性
Specificity and Nonspecificity of Amygdala in Emotional Processing
DOI: 10.12677/AP.2021.118208, PDF,  被引量    国家科技经费支持
作者: 冯 柔, 何正明, 王福顺:四川师范大学脑与心理科学研究院,四川 成都
关键词: 杏仁核情绪加工效价唤醒度Amygdala Emotional Processing Valence Arousal
摘要: 情绪与个体的身心健康息息相关,杏仁核是情绪加工的重要中枢,杏仁核受损会严重影响动物和人类对恐惧情绪的识别、反应与学习。然而脑成像研究结果发现,除恐惧情绪外,其他基本情绪也能激活杏仁核,因此杏仁核在情绪效价加工中可能具有非特异性。相反,杏仁核的关键作用或许取决于情绪刺激的高唤醒度,与注意网络等有重要关系。以及,杏仁核半侧功能不对称性的特点,对解析其在情绪加工中脑成像研究结果存在一定干扰。本文从情绪的效价和唤醒维度出发,对杏仁核的特异性与非特异性加工作用进行探讨,以期为未来情绪障碍的临床治疗提供指导意义。
Abstract: Emotions are closely related to an individual’s physical and mental health, and the amygdala is an important center of emotional processing. The damage of the amygdala will seriously affect the recognition, response and learning of fear in animals or humans. However, the results of brain imaging technology showed that emotional valence could not explain the specific response of emotional activation in the amygdala. Besides fear, other basic emotions could also activate the amygdala. The key role of the amygdala in emotion recognition may depend on high arousal and is important to the attention network; any survival significance of the stimulus can be quickly detected by the amygdala. And the amygdala has a semi-functional asymmetry, which has a certain interference effect on the study of emotional function of amygdala using brain imaging technology.
文章引用:冯柔, 何正明, 王福顺 (2021). 杏仁核在情绪加工中的特异性与非特异性. 心理学进展, 11(8), 1863-1870. https://doi.org/10.12677/AP.2021.118208

参考文献

[1] 陈珊珊, 蔡厚德(2015). 丘脑枕核参与情绪信息加工的多条通路. 心理科学进展, 23(2), 234-240.
[2] 冯攀, 冯廷勇(2013). 恐惧情绪加工的神经机制. 心理学探新, 33(3), 209-214.
[3] 傅小兰(2014). 情绪心理学. 上海: 华东师范大学出版社.
[4] 胡登宇, 刘芳芳, 陈旭(2018). 杏仁核在恐惧识别与恐惧体验中特异性作用的分离. 中国临床心理学杂志, 26(4), 688-693.
[5] 李贺, 蔡厚德(2013). 情绪对注意功能网络的调制. 心理科学进展, 21(1), 59-67.
[6] 刘丽(2021). 正念疗法改善不良情绪的研究进展. 心理月刊, 16(14), 224-225.
[7] 苏彦捷(译) (2016). 生理心理学走进行为神经科学的世界(第9版). 北京: 中国轻工业出版社. (R. Carlson, 2016)
[8] 王翠艳, 刘昌(2007). 杏仁核情绪功能偏侧化的成像研究述评. 心理科学进展, 15(2), 313-318.
[9] 逸明(2016). 70%的疾病与情绪有关. 长寿, (10), 22-23.
[10] Adolphs, R., Gosselin, F., Buchanan, T. W., Tranel, D., Schyns, P., & Damasio, A. R. (2005). A Mechanism for Impaired Fear Recognition after Amygdala Damage. Nature, 433, 65-68.[CrossRef] [PubMed]
[11] Alexander, T., & Engell, A. D. (2008). The Role of the Amygdala in Implicit Evaluation of Emotionally Neutral Faces. Social Cognitive Affective Neuroscience, 3, 303-312.[CrossRef] [PubMed]
[12] Avecillas-Chasin, J. M., Justo, M., Levinson, S., Koek, R., Krahl, S. E., Chen, J. W., Bari, A. et al. (2020). Structural Correlates of Emotional Response to Electrical Stimulation of the Amygdala in Subjects with PTSD. Brain Stimulation, 13, 424-426.[CrossRef] [PubMed]
[13] Baas, D., Aleman, A., & Kahn, R. S. (2004). Lateralization of Amygdala Activation: A Systematic Review of Functional Neuroimaging Studies. Brain Research Reviews, 45, 96-103.[CrossRef] [PubMed]
[14] Balconi, M., & Cobelli, C. (2015). rTMS on Left Prefrontal Cortex Contributes to Memories for Positive Emotional Cues: A Comparison between Pictures and Words. Neuroscience, 287, 93-103.[CrossRef] [PubMed]
[15] Bayet, L., Quinn, P. C., Laboissière, R., Caldara, R., Lee, K., & Pascalis, O. (2017). Fearful But Not Happy Expressions Boost Face Detection in Human Infants. Proceedings of the Royal Society B: Biological Sciences, 284, Article ID: 20171054.[CrossRef] [PubMed]
[16] Breiter, H. C., Etcoff, N. L., Whalen, P. J., Kennedy, W. A., Rauch, S. L., Buckner, R. L., Rosen, B. R. et al. (1996). Response and Habituation of the Human Amygdala during Visual Processing of Facial Expression. Neuron, 17, 875-887.[CrossRef
[17] Costafreda, S. G., Brammer, M. J., David, A. S., & Fu, C. H. Y. (2008). Predictors of Amygdala Activation during the Processing of Emotional Stimuli: A Meta-Analysis of 385 PET and fMRI Studies. Brain Research Reviews, 58, 57-70.[CrossRef] [PubMed]
[18] Ekman, P. (1999). Basic Emotions. In T. Dalgleish, & M. J. Power (Eds.), Handbook of Cognition Emotion (pp. 45-60). John Wiley and Son Ltd.[CrossRef
[19] Gerbella, M., Caruana, F., & Rizzolatti, G. (2017). Pathways for Smiling, Disgust and Fear Recognition in Blindsight Patients. Neuropsychologia, 128, 6-13.[CrossRef] [PubMed]
[20] Glascher, J., & Adolphs, R. (2003). Processing of the Arousal of Subliminal and Supraliminal Emotional Stimuli by the Human Amygdala. The Journal of Neuroscience, 23, 10274-10282.[CrossRef
[21] Juruena, M. F., Giampietro, V. P., Smith, S. D., Surguladze, S. A., Dalton, J. A., Benson, P. J., Fu, C. H. Y. et al. (2009). Amygdala Activation to Masked Happy Facial Expressions. Journal of the International Neuropsychological Society, 16, 383-387.[CrossRef
[22] Kensinger, E. A., & Schacter, D. L. (2006). Processing Emotional Pictures and Words: Effects of Valence and Arousal. Cognitive, Affective & Behavioral Neuroscience, 6, 110-126.[CrossRef
[23] Kosaka, H., Omori, M., Murata, T., Iidaka, T., Yamada, H., Okada, T., Wada, Y. et al. (2002). Differential Amygdala Response during Facial Recognition in Patients with Schizophrenia: An fMRI Study. Schizophrenia Research, 57, 87.[CrossRef
[24] Kouptsova, J. E., Leung, R. C., & Taylor, M. J. (2017). Stimulus Exposure Duration Alters Implicit Processing of Neutral and Emotional Faces. Neuroscience, 341, 154-159.[CrossRef] [PubMed]
[25] LeDoux, J. (2003). The Emotional Brain, Fear, and the Amygdala. Cellular and Molecular Neurobiology, 23, 727-738.[CrossRef
[26] LeDoux, J. E. (2014). Coming to Terms with Fear. Proceedings of the National Academy of Sciences of the United States of America, 111, 2871-2878.[CrossRef] [PubMed]
[27] Martynova, O., Tetereva, A., Balaev, V., Portnova, G., Ushakov, V., & Ivanitsky, A. (2020). Longitudinal Changes of Resting-State Functional Connectivity of Amygdala Following Fear Learning and Extinction. International Journal of Psychophysiology, 149, 15-24.[CrossRef] [PubMed]
[28] Méndez-Bértolo, C., Moratti, S., Toledano, R., Lopez-Sosa, F., Martínez-Alvarez, R., Mah, Y. H., Strange, B. A. et al. (2016). A Fast Pathway for Fear in Human Amygdala. Nature Neuroscience, 19, 1041-1049.[CrossRef] [PubMed]
[29] Morris, J. S., Ohman, A., & Dolan, R. J. (1998). Conscious and Unconscious Emotional Learning in the Human Amygdala. Nature, 393, 467-470.[CrossRef] [PubMed]
[30] Ono, T., & Nishijo, H. (1992). Neurophysiological Basis of the Klüver-Bucy Syndrome: Responses of Monkey Amygdaloid Neurons to Biologically Significant Objects. In J. Aggleton (Ed.), The Amygdala: Neurobiological Aspects of Emotion, Memory, and Mental Dysfunction (pp. 167-190). John Wiley & Sons.
[31] Pedersen, W. S., Muftuler, L. T., & Larson, C. L. (2017). Disentangling the Effects of Novelty, Valence and Trait Anxiety in the Bed Nucleus of the Stria Terminalis, Amygdala and Hippocampus with High Resolution 7T fMRI. NeuroImage, 156, 293-301.[CrossRef] [PubMed]
[32] Phillips, M. L., Medford, N., Young, A. W., Williams, L., Williams, S. C. R., Bullmore, E. T., Brammer, M. J. et al. (2001). Time Courses of Left and Right Amygdalar Responses to Fearful Facial Expressions. Human Brain Mapping, 12, 193-202.[CrossRef
[33] Posner, J., Russell, J. A., & Peterson, B. S. (2005). The Circumplex Model of Affect: An Integrative Approach to Affective Neuroscience, Cognitive Development, and Psychopathology. Development Psychopathology, 17, 715-734.[CrossRef
[34] Russell, J. A. (2003). Psychological Construction of Emotion. Psychological Review, 110, 145-172.[CrossRef
[35] Sabatinelli, D., & Frank, D. W. (2019). Assessing the Primacy of Human Amygdala-Inferotemporal Emotional Scene Discrimination with Rapid Whole-Brain fMRI. Neuroscience, 406, 212-224.[CrossRef] [PubMed]
[36] Schneider, F., Grodd, W., Weiss, U., Klose, U., Mayer, K. R., Nagele, T., & Gur, R. C. (1997). Functional MRI Reveals Left Amygdala Activation during Emotion. Psychiatry Research: Neuroimaging Section, 76, 75-82.[CrossRef
[37] Small, D. M., Gregory, M. D., Mak, Y. E., Gitelman, D., Mesulam, M. M., & Parrish, T. (2003). Dissociation of Neural Representation of Intensity and Affective Valuation in Human Gustation. Neuron, 39, 701-711.[CrossRef
[38] Susan, S. et al. (2020). Know Safety, No Fear. Neuroscience and Biobehavioral Reviews, 108, 218-310.[CrossRef] [PubMed]
[39] Tippett, D. C., Godin, B. R., Oishi, K., Oishi, K., Davis, C., Gomez, Y., Hillis, A. E. et al. (2018). Impaired Recognition of Emotional Faces after Stroke Involving Right Amygdala or Insula. Seminars in Speech and Language, 39, 87-100.[CrossRef] [PubMed]
[40] Tottenham, N., & Gabard-Durnam, L. J. (2017). The Developing Amygdala: A Student of the World and a Teacher of the Cortex. Current Opinion in Psychology, 17, 55-60.[CrossRef] [PubMed]
[41] Tsuchiya, N., Moradi, F., Felsen, C., Yamazaki, M., & Adolphs, R. (2009). Intact Rapid Detection of Fearful Faces in the Absence of the Amygdala. Nature Neuroscience, 12, 1224-1225.[CrossRef] [PubMed]
[42] Wang, J. F., & Wu, Y. (2019). Self-Esteem Modulates the ERP Processing of Emotional Intensity in Happy and Angry Faces. PLoS ONE, 14, e0217844.[CrossRef] [PubMed]