光稳定剂中间体2-氯-4,6-二(N-丁基-2,2,6,6-四甲基-4-哌啶胺基)-1,3,5-三嗪的合成研究

Synthetic Research of Light Stabilizer Intermediate 2-Chloro-4,6-Bis(N-Butyl- 2,2,6,6-Tetramethyl-4-Piperidinyl)-1,3,5-Triazine

摘要: 采用单因素法，以三聚氯氰、N-丁基-2,2,6,6-四甲基-4-哌啶胺和氢氧化钠为原料，二甲苯为溶剂，四丁基溴化铵为催化剂合成光稳定剂中间体2-氯-4,6-二(N-丁基-2,2,6,6-四甲基-4-哌啶胺基)-1,3,5-三嗪。结果表明该反应的最优工艺条件为第一阶段反应温度为5℃~8℃，反应时间2 h，第二阶段升温至60℃，反应时间5 h，原料物质的量之比n(三聚氯氰):n(N-丁基-2,2,6,6-四甲基-4-哌啶胺):n(氢氧化钠) = 1:2.15:2.15，催化剂四丁基溴化铵的用量0.20 g (相对0.05 mol三聚氯氰)，产品产率为95.61%。

Abstract: The light stabilizer intermediate 2-chloro-4,6-bis(n-butyl-2,2,6,6-tetramethyl-4-piperidinyl)-1,3,5- triazine was synthesized by single factor method with cyanuric chloride, n-butyl-2,2,6,6-tetra- me-thyl-4-piperidinyl and sodium hydroxide as raw materials, xylene as solvent and tetrabutyl ammo-nium bromide as catalyst. The results showed that the optimum reaction conditions were as follows: the reaction temperature in the first stage was 5˚C~8˚C, the reaction time was 2 h, the temperature in the second stage was raised to 60˚C, the reaction time was 5 h, the ratio of raw material n(cyanuric chloride):n(n-butyl-2,2,6,6-tetramethyl-4-piperidine):n(sodium hydroxide) = 1:2.15:2.15, the amount of catalyst tetrabutyl ammonium bromide was 0.20 g (relative to 0.05 mol cyanuric chloride), the yield of the product was 95.61%.