三皮愈疡汤灌肠联合小剂量美沙拉嗪口服治疗溃疡性结肠炎45例

Treatment of 45 Cases of Ulcerative Colitis by Enema of Sanpi Yuyang Decoction Combined with Oral Administration of Low-Dose Mesalazine

摘要: 目的：探究溃疡性结肠炎应用小剂量美沙拉嗪联合中药灌肠治疗的效果。方法：选择2009年12月~2019年12月三亚市中医院溃疡性结肠炎患者90例为研究对象，按随机分成对照组和治疗组，每组各45例。对照组给予美沙拉嗪口服治疗，治疗法组给予小剂量美沙拉嗪口服联合灌肠治疗。分析两组患者的临床治疗效果、黏膜组织变化和不良反应情况。结果：治疗组患者治疗的有效率为91.11%，高于对照组(66.66%)，差异有统计学意义(P < 0.05)；结论：对溃疡性结肠炎患者予以小剂量美沙拉嗪联合中药灌肠治疗，能够有效提升临床疗效，具有一定临床应用和研究价值。

Abstract: Objective: To explore the effect of low-dose mesalazine combined with traditional Chinese medi-cine enema in the treatment of ulcerative colitis. Methods: 90 patients with ulcerative colitis in Sanya Hospital of traditional Chinese medicine from December 2009 to December 2019 were randomly divided into control group and treatment group, with 45 cases in each group. The con-trol group was treated with mesalazine orally, and the treatment group was treated with low-dose mesalazine orally combined with enema. The clinical therapeutic effect, mucosal tissue changes and adverse reactions of the two groups were analyzed. Results: The effective rate of the treatment group was 91.11%, which was higher than that of the control group (66.66%) (P < 0.05); Conclusion: Small dose mesalazine combined with traditional Chinese medicine enema can effectively improve the clinical efficacy and has certain clinical application and research value.