肝切除术前肝脏储备功能的评估及研究进展

Assessment and Research Progress of Liver Reserve Function before Hepatectomy

摘要: 术后肝脏衰竭仍然是肝脏手术的主要并发症之一。肝功能的术前评价对于降低肝切除或肝移植术后的并发症至关重要。随着医疗技术的发展及精准肝脏切除理念的提出，术前肝脏储备功能的评估显得越来越重要。目前应用于肝脏储备功能评估的各种方法主要包括血清学指标、临床评分系统(如Child-Pugh、MELD评分和白蛋白–胆红素(ALBI)评分)、动态定量检测肝脏清除功能(如吲哚箐绿清除试验)、CT容量评估等。目前针对评价肝功能的检查方法很多，但是没有哪一种评估方法能够全面且精准有效地评价肝脏储备功能。因此，需要结合多种检查方法以更加全面地评价肝脏储备功能。本文针对肝脏储备功能评估检查新近进展予以综述。

Abstract: Postoperative liver failure is still one of the main complications of liver surgery. Preoperative evaluation of liver function is critical to reducing complications after liver resection or liver transplantation. With the development of medical technology and the proposal of precise liver resection, the evaluation of preoperative liver reserves is more important. The various methods currently applied to the liver reserve functional assessment mainly include serological indicators, clinical scoring systems (such as Child-Pugh, MELD rating and albumin-bilirubin (ALBI) score), dynamic quantitative detection of liver clearance function (such as indocyanine green retention test), CT capacity assessment, etc. There are currently a lot of inspection methods for evaluating liver function, but no evaluation method can comprehensively and accurately evaluate liver reserves. Therefore, there is a need to combine a variety of inspection methods to the more comprehensive evaluation of liver reserves. This paper summarizes new progress on the evaluation of liver reserves.