幽门螺旋杆菌感染程度与胃癌及胃相关疾病的相关性分析
Correlation between Helicobacter pylori Infection and Gastric Cancer and Gastric Related Diseases
DOI: 10.12677/ACM.2021.119625, PDF,    科研立项经费支持
作者: 黄 海, 张明凯, 孙梅华, 李燕彬*：滨州医学院附属医院胃肠外科，山东 滨州；彭志浩：东营市胜利油田中心医院，山东 东营；王建平：滨州市中心医院，山东 滨州
关键词: 幽门螺旋杆菌；胃癌前病变；胃癌；Helicobacter pylori； Precancerous Lesions of Gastric Cancer； Gastric Cancer
摘要: 目的：探讨幽门螺旋杆菌感染程度对胃癌及胃相关疾病的影响。方法：选取我院2012年9月至2016年9月在我院行胃镜检查的患者共8023例，通过分析年龄、性别、幽门螺旋杆菌感染程度对胃癌及胃相关疾病的影响，探讨其相关性。结果：年龄、性别、幽门螺旋杆菌感染与胃癌及胃相关疾病的发生差异具有统计学意义(P < 0.05)。进一步对发生胃癌的病人的发生部位进行单独分析发现HP阳性以胃窦部癌变为主，且胃窦癌变的风险与幽门螺旋杆菌阳性程度成正比。结论：性别、年龄、幽门螺旋杆菌感染程度与胃癌及胃相关疾病的发生有关，进一步发现幽门螺旋杆菌感染与胃癌发生部位密切相关。
Abstract: Objective: To investigate the effect of Helicobacter pylori infection on gastric cancer and gastric related diseases. Methods: A total of 8023 patients who underwent gastroscopy in our hospital from September 2012 to September 2016 were selected to explore the correlation by analyzing the effects of age, gender and Helicobacter pylori infection on gastric cancer and gastric related diseases. Results: There were significant differences between age, sex, Helicobacter pylori infection and gastric cancer and gastric related diseases (P < 0.05). Further analysis of the location of gastric cancer patients showed that HP positive was mainly gastric antrum carcinogenesis, and the risk of gastric antrum carcinogenesis was directly proportional to the positive degree of Helicobacter pylori. Conclusion: Gender, age and the degree of Helicobacter pylori infection were related to the occurrence of gastric cancer and gastric related diseases. It was further found that Helicobacter pylori infection was closely related to the location of gastric cancer.
文章引用：黄海, 张明凯, 彭志浩, 王建平, 孙梅华, 李燕彬. 幽门螺旋杆菌感染程度与胃癌及胃相关疾病的相关性分析[J]. 临床医学进展, 2021, 11(9): 4267-4274. https://doi.org/10.12677/ACM.2021.119625

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