翼状胬肉治疗的研究进展
Advances in the Treatment of Pterygium
DOI: 10.12677/ACM.2021.1110651, PDF,   
作者: 朱 钰*:济宁医学院临床医学院,山东 济宁;李永华#:济宁医学院附属医院,山东 济宁
关键词: 翼状胬肉治疗手术Pterygium Treatment Surgery
摘要: 翼状胬肉是一种从球结膜向角结膜生长的纤维血管组织,是一种常见的眼表疾病。手术切除是其主要治疗方式。近几年医学技术迅速发展,但翼状胬肉复发问题还未解决。很多方法可以预防胬肉的复发,但是对于哪种方法最有效还没有一个明确的观点。由于复发性胬肉比原发性胬肉更具有侵袭性,所以确定复发率最低的治疗方法非常关键。本文旨在评估比较文献中翼状胬肉的治疗与其复发率,总结合理有效的治疗方法。
Abstract: Pterygium is a kind of fibrous vascular tissue from bulbar conjunctiva to corneal, which is a common ocular surface disease. Surgical excision is the main treatment. Medical techniques have developed rapidly in recent years, pterygium still recurs. There are many methods to prevent the recurrence of pterygium, but there is no clear view on which method is most effective. Since recurrent pterygium is more aggressive than primary pterygium, it is critical to determine the treatment with the lowest recurrence rate. This article aims to evaluate and compare the treatment and recurrence rate of pterygium and summarize the reasonable and effective treatment methods.
文章引用:朱钰, 李永华. 翼状胬肉治疗的研究进展[J]. 临床医学进展, 2021, 11(10): 4445-4450. https://doi.org/10.12677/ACM.2021.1110651

参考文献

[1] Hill, J.C. and Maske, R. (1989) Pathogenesis of Pterygium. Eye, 3, 218-226. [Google Scholar] [CrossRef] [PubMed]
[2] Mohammed, I. (2011) Treatment of Pterygium. Annals of African Medicine, 10, 197-203. [Google Scholar] [CrossRef] [PubMed]
[3] Cameron, M.E. (1965) Pterygium throughout the World. Charles C. Thomas, Springfield.
[4] Coroneo, M.T., Giirolamo, N.D. and Wakefield, D. (1999) Thepathogenesis of Pterygia. Current Opinion in Opthalmology, 10, 282-288. [Google Scholar] [CrossRef] [PubMed]
[5] Butrus, S.I., Ashaf, M.F., Laby, D.M., Rabinovvitz, A.L., Tabbara, S.O. and Hidayat, A.A. (1995) Increased Numbers of Mast Cellsin Pterygia. American Journal of Ophthalmology, 119, 236-237. [Google Scholar] [CrossRef
[6] Di Girolamo, N., Chui, J., Coroneo, M.T. and Wakefield. D. (2004) Pathogenesis of Pterygia: Role of Cytokines, Growth Factors, and Matrix Metalloproteinases. Progress in Retinal and Eye Research, 23, 195-228. [Google Scholar] [CrossRef] [PubMed]
[7] Tekelioglu, Y., Turk, A., Avunduk, A.M. and Yulug, E. (2006) Flow Cytometrical Analysis of Adhesion Molecules, T-Lymphocytesub Populations and Inflammatory Markers in Pterygium. Ophthalmologica, 220, 372-378. [Google Scholar] [CrossRef] [PubMed]
[8] Hirst, L.W. (2003) The Treatment of Pterygium. Survey of Ophthalmology, 48, 145-180. [Google Scholar] [CrossRef
[9] Alpay, A., Ugurbas, S. and Erdoğan, B. (2009) Comparing Techniques for Pterygıum. Clinical Ophthalmology, 3, 69-74. [Google Scholar] [CrossRef
[10] Ozer, A., Yildirim, N., Erol, N. and Yurdakul, S. (2009) Long-Termresults of Bare Sclera, Limbal-Conjunctival Autograft Andamniotic Membrane Graft Techniques in Primary Pterygium Excisions. Ophthalmologica, 223, 269-273. [Google Scholar] [CrossRef] [PubMed]
[11] Kareem, A.A., Farhoood, Q. and Alhammami, H. (2012) The Use of Antimetabolites as Adjunctive Therapy in the Surgical Treatment of Pterygium. Clinical Ophthalmology, 6, 1849-1854. [Google Scholar] [CrossRef
[12] Yanyali, A.C., Talu, H., Alp, B.N., Karabas, L., Ay, G.M. and Caglar, Y. (2000) Intraoperative Mitomycin C in the Treatment of Pterygium. Cornea, 19, 471-473. [Google Scholar] [CrossRef] [PubMed]
[13] Demirok, A., Simsek, S., Cinal, A. and Yasar, T. (1998) Intraoperative Application of Mitomycin C in the Surgical Treatment of Pterygium. European Journal of Ophthalmology, 8, 153-156. [Google Scholar] [CrossRef] [PubMed]
[14] Kenyon, K.R., Wagoner, M.D. and Hettinger, M.E. (1985) Conjunctival Autograft Transplantation for Advanced and Recurrent Pterygium. Ophthalmology, 92, 1461-1470. [Google Scholar] [CrossRef
[15] Kmiha, N., Kamoun, B., Trigui, A., Jelliti, B., Fourati, M. and Chaabouni, M. (2001) Effectiveness of Conjunctival Autograft Transplantation in Pterygium Surgery. Journal Français D’Ophtalmologie, 24, 729-732.
[16] Seid, A. and Bejiga, A. (2000) Free Conjunctival Autograft in Themanagement of Advanced Primary and Recurrent Pterygia. East African Medical Journal, 77, 588-591. [Google Scholar] [CrossRef] [PubMed]
[17] Chaidaroon, W. and Wattananikorn, S. (2003) Conjunctival Autograft Transplantation for Primary Pterygium. Journal of the Medical Association of Thailand, 86, 111-115.
[18] Huerva, V., March, A., Martinez-Alonso, M., Muniesa, M.J. and Sanchez, C. (2012) Pterygium Surgery by Means of Conjunctival Autograft: Long Term Follow-Up. Arquivos Brasileiros de Oftalmologia, 75, 251-255. [Google Scholar] [CrossRef
[19] Varssano, D., Shalev, H., Lazar, M. and Fischer, N. (2013) Pterygium Excision with Conjunctival Autograft: True Survival Rate Statistics. Cornea, 32, 1243-1250. [Google Scholar] [CrossRef
[20] Kocamis, O. and Bilgec, M. (2014) Evaluation of the Recurrencerate for Pterygium Treated with Conjunctival Autograft. Graefe’s Archive for Clinical and Experimental Ophthalmology, 252, 817-820. [Google Scholar] [CrossRef] [PubMed]
[21] Koranyi, G., Seregard, S. and Kopp, E.D. (2005) The Cut-and-Pastemethod for Primary Pterygium Surgery: Long-Term Followup. Acta Ophthalmologica Scandinavica, 83, 298-301. [Google Scholar] [CrossRef] [PubMed]
[22] Bahar, I., Weinberger, D., Dan, G. and Avisar, R. (2006) Pterygiumsurgery: Fibrin Glue versus Vicryl Sutures for Conjunctival Closure. Cornea, 25, 1168-1172. [Google Scholar] [CrossRef] [PubMed]
[23] Al-Fayez, M.F. (2002) Limbal versus Conjunctival Autograft Transplantation for Advanced and Recurrent Pterygium. Ophthalmology, 109, 1752-1755. [Google Scholar] [CrossRef
[24] Malik, K.P., Goel, R., Gutpa, A., Gupta, S.K., Kamal, S., Mallik, V.K. and Singh, S. (2012) Efficacy of Sutureless and Glue Freelimbal Conjunctival Autograft for Primary Pterygium Surgery. Nepalese Journal of Ophthalmology, 4, 230-235. [Google Scholar] [CrossRef] [PubMed]
[25] Al Fayez, M.F. (2013) Limbal-Conjunctival versus Conjunctival Autograft Transplant for Recurrent Pterygia: A Prospective Randomized Controlled Trial. JAMA Ophthalmology, 131, 11-16. [Google Scholar] [CrossRef] [PubMed]
[26] Masters, J.S. and Harris Jr., D.J. (2015) Low Recurrence Rate of Pterygium after Excision with Conjunctival Limbal Autograft: A Retrospective Study with long-Term Follow-Up. Cornea, 34, 1569-1572. [Google Scholar] [CrossRef
[27] Shimazaki, J., Shinozaki, N. and Tsubota, K. (1998) Transplantation of Amniotic Membrane and Limbal Autograft for Patients with Recurrent Pterygium Associated with Symblepharon. British Journal of Ophthalmology, 82, 235-240. [Google Scholar] [CrossRef] [PubMed]
[28] Shimazaki, J., Kosaka, K., Shimmura, S. and Tsubota, K. (2003) Amniotic Membrane Transplantation with Conjunctival Autograft for Recurrent Pterygium. Ophthalmology, 110, 119-124. [Google Scholar] [CrossRef
[29] Küçükerdönmez, C., Akova, Y.A. and Altinors, D.D. (2007) Comparison of Conjunctival Autograft with Amniotic Membrane Transplantation for Pterygium Surgery: Surgical and Cosmetic Outcome. Cornea, 26, 407-413. [Google Scholar] [CrossRef
[30] Okoye, O., Oguego, N.C., Chuka Okosa, C.M. and Ghanta, M. (2013) Short Term Results of Pterygium Surgery with Adjunctive Amniotic Membrane Graft. Nigerian Journal of Clinical Practice, 16, 356-359. [Google Scholar] [CrossRef] [PubMed]
[31] Arain, M.A., Yaqub, M.A., Ameen, S.S., Iqbal, Z., Naqvi, A.H. and Niazi, M.K. (2012) Amniotic Membrane Transplantation Inprimary Pterygium Compared with Bare Sclera Technique. Journal of College of Physicians and Surgeons Pakistan, 22, 440-443.
[32] Solomon, A., Pires, R.T. and Tseng, S.C. (2001) Amniotic Membrane Transplantation after Extensive Removal of Primaryand Recurrent Pterygia. Ophthalmology, 108, 449-460. [Google Scholar] [CrossRef
[33] Essex, R.W., Snibson, G.R., Daniell, M. and Tole, D.M. (2004) Amniotic Membrane Grafting in the Surgical Management of Primary Pterygium. Clinical & Experimental Ophthalmology, 32, 501-504. [Google Scholar] [CrossRef] [PubMed]
[34] Liang, W., Li, R. and Deng, X. (2012) Comparison of the Efficacy of Pterygium Resection Combined with Conjunctival Autograft versus Pterygium Resection Combined with Amniotic Membrane Transplantation. Eye Science, 27, 102-105.
[35] Tananuvat, N. and Martin, T. (2004) The Results of Amniotic Membrane Transplantation for Primary Pterygium Compared with Conjunctival Autograft. Cornea, 23, 458-463. [Google Scholar] [CrossRef] [PubMed]
[36] Luanratanakorn, P., Ratanapakorn, T., Suwan-Apichon, O. and Chuck, R.S. (2006) Randomised Controlled Study of Conjunctival Autograft versus Amniotic Membrane Graft in Pterygium Excision. British Journal of Ophthalmology, 90, 1476-1480. [Google Scholar] [CrossRef] [PubMed]
[37] Ngoy, D. and Kayembe, L. (1998) A Comparative Study of Thiotepa and Mitomycin C in the Treatment of Pterygium. Preliminary Results. Journal Français D’Ophtalmologie, 21, 96-102.
[38] Tassy, A. and Ribe, D. (1999) Thiotepa Eye Drops for Prevention of Pterygium Recurrence: 18 Years of Use. Journal Français D’Ophtalmologie, 22, 215-219.
[39] 吴河坪, 陈国策. 环胞霉素A和噻替哌预防翼状胬肉术后复发[J]. 眼科学报, 1999, 15(2): 91-92.
[40] Akarsu, C., Taner, P. and Ergin, A. (2003) 5-Fluorouracil Aschemoadjuvant for Primary Pterygium Surgery: Preliminary Report. Cornea, 22, 522-526. [Google Scholar] [CrossRef] [PubMed]
[41] Bekibele, C.O., Baiyeroju, A.M., Olusanya, B.A., Ashaye, A.O. and Oluleye, T.S. (2008) Pterygium Treatment Using 5-FU as Adjuvant Treatment Compared to Conjunctiva Autograft. Eye, 22, 31-34. [Google Scholar] [CrossRef] [PubMed]
[42] Bekibele, C.O., Ashaye, A., Olusanya, B., Baiyeroju, A., Fasina, O., Ibrahim, A.O. and Ogun, O. (2012) 5-Fluorouracil versus Mitomycin C as Adjuncts to Conjunctival Autograft in Preventingpterygium Recurrence. International Ophthalmology, 32, 3-8. [Google Scholar] [CrossRef] [PubMed]
[43] Salustiano Correa, E., Silva, R., de Pereira Avila, M., Rassi, A.R., Ximenes, L., da Silva Jr., D.S. and de Paula, A.C. (2013) Intraoperative Use of 5-Fluorouracil in Pterygium Surgery: A Comparative Study. Seminars in Ophthalmology, 28, 34-36. [Google Scholar] [CrossRef] [PubMed]