|
[1]
|
Parkin, D.M., Pisani, P., Muñoz, N. and Ferlay, J. (1999) The Global Health Burden of Infection. In: Newton, R., Beral, V. and Weiss, R.A., Eds., Infections and Human Cancer, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, 5-33.
|
|
[2]
|
Yao, R.R., Li, J.H., Zhang, R., Chen, R.X. and Wang, Y.H. (2018) M2-Polarized Tumor-Associated Macrophages Facilitated Migration Epithelial-Mesenchymal Transition of HCC Cells via the TLR4/STA T3 Signaling Pathway. World Journal of Surgical Oncology, 16, 9. [Google Scholar] [CrossRef] [PubMed]
|
|
[3]
|
Edmunds, W.J., et al. (1993) The Influence of Age on the Development of the Hepatitis B Carrier State. Proceedings of the Royal Society B: Biological Sciences, 253, 197-201. [Google Scholar] [CrossRef] [PubMed]
|
|
[4]
|
Castello, G., et al. (2010) HCV-Related Hepatocellular Carcinoma: From Chronic Inflammation to Cancer. Clinical Immunology, 134, 237-250. [Google Scholar] [CrossRef] [PubMed]
|
|
[5]
|
Zheng, L., You, N., Huang, X., Gu, H., Wu, K., Mi, N. and Li, J. (2019) COMMD7 Regulates NF-kappaB Signaling Pathway in Hepatocellular Carcinoma Stem-Like Cells. Molecular Therapy—Oncolytics, 12, 112-123. [Google Scholar] [CrossRef] [PubMed]
|
|
[6]
|
Porta, C., Riboldi, E. and Sica, A. (2011) Mechanisms Linking Pathogens-Associated Inflammation and Cancer. Cancer Letters, 305, 250-262. [Google Scholar] [CrossRef] [PubMed]
|
|
[7]
|
Leonardi, G.C., Candido, S., Cervello, M., et al. (2012) The Tumor Microenvironment in Hepatocellular Carcinoma. International Journal of Oncology, 40, 1733-1747.
|
|
[8]
|
Luedde, T. and Schwabe, R.F. (2011) NF-κB in the Liver-Linking Injury, Fibrosis and Hepatocellular Carcinoma. Nature Review Gastroenterology and Hepatology, 8, 108-118. [Google Scholar] [CrossRef] [PubMed]
|
|
[9]
|
Yang, J.D., Nakamura, I. and Roberts, L.R. (2011) The Tumor Microenvironment in Hepatocellular Carcinoma: Current Status and Therapeutic Targets. Seminars in Cancer Biology, 21, 35-43. [Google Scholar] [CrossRef] [PubMed]
|
|
[10]
|
Giannitrapani, L., Cervello, M., Soresi, M., Notarbartolo, M., La Rosa, M., Virruso, L., D’Alessandro, N. and Montalto, G. (2002) Circulating IL-6 and sIL-6R in Patients with Hepatocellular Carcinoma. Annals of the New York Academy of Sciences, 963, 46-52. [Google Scholar] [CrossRef] [PubMed]
|
|
[11]
|
Roberts, L.R. (2016) Biomarkers for Hepatocellular Carcinoma. Gastroenterology & Hepatology, 12, 252-255.
|
|
[12]
|
Kao, J.T., Feng, C.L., Yu, C.J., Tsai, S.M., Hsu, P.N., Chen, Y.L. and Wu, Y.Y. (2015) IL-6, through p-STAT3 Rather than p-STAT1, Activates Hepatocarcinogenesis and Affects the Survival of Hepatocellular Carcinoma Patients: A Cohort Study. BMC gastroenterology, 15, 50. [Google Scholar] [CrossRef] [PubMed]
|
|
[13]
|
Liu, R., Tang, C., Shen, A., et al. (2016) IL-37 Suppresses Hepatocellular Carcinoma Growth by Converting pSmad3 Signaling from JNK/pSmad3L/c-Myc Oncogenic Signaling to pSmad3C/P21 Tumor-Suppressive Signaling. Oncotarget, 7, 85079-85096. [Google Scholar] [CrossRef] [PubMed]
|
|
[14]
|
Lee, Y.J. and Jang, B.K. (2015) The Role of Autophagy in Hepatocellular Carcinoma. International Journal of Molecular Sciences, 16, 26629-26643. [Google Scholar] [CrossRef] [PubMed]
|
|
[15]
|
Li, T.T., Zhu, D., Mou, T., et al. (2017) IL-37 Induces Autophagy in Hepatocellular Carcinoma Cells by Inhibiting the PI3K/AKT/mTOR Pathway. Molecular Immunology, 87, 132-140. [Google Scholar] [CrossRef] [PubMed]
|
|
[16]
|
Xiang, Z.L., et al. (2009) Chemokine Receptor CXCR4 Expression in Hepatocellular Carcinoma Patients Increases the Risk of Bone Metastases and Poor Survival. BMC Cancer, 9, 176. [Google Scholar] [CrossRef] [PubMed]
|
|
[17]
|
Du, D., et al. (2014) The Effects of the CCR6/CCL20 Biological Axis on the Invasion and Metastasis of Hepatocellular Carcinoma. International Journal of Molecular Sciences, 15, 6441-6452. [Google Scholar] [CrossRef] [PubMed]
|
|
[18]
|
Yeung, O.W., et al. (2015) Alternatively, Activated (M2) Macrophages Promote Tumor Growth and Hepatocellular Carcinoma Invasiveness. Journal of Hepatology, 62, 607-616. [Google Scholar] [CrossRef] [PubMed]
|
|
[19]
|
Leng, J., Han, C., Demetris, A.J., et al. (2003) Cyclooxygenase-2 Promotes Hepatocellular Carcinoma Cell Growth through Akt Activation: Evidence for Akt Inhibition in Celecoxib Induces Apoptosis. Hepatology, 38, 756-768. [Google Scholar] [CrossRef] [PubMed]
|
|
[20]
|
Dajani, O.F., Meisdalen, K., Guren, T.K., Aasrum, M., Tveteraas, I.H., Lilleby, P., Thoresen, G.H., Sandnes, D. and Christoffersen, T. (2008) Prostaglandin E2 Upregulates EGF-Stimulated Signaling in Mitogenic Pathways Involving Akt and ERK in Hepatocytes. Journal of Cellular Physiology, 214, 371-380. [Google Scholar] [CrossRef] [PubMed]
|
|
[21]
|
Hatziapostolou, M., Polytarchou, C., Aggelidou, E., Drakaki, A., Poultsides, G.A., Jaeger, S.A., Ogata, H., Karin, M., Struhl, K., Hadzopoulou-Cladaras, M. and Iliopoulos, D. (2011) An HNF4α-miRNA an Inflammatory Feedback Circuit Regulates Hepatocellular Oncogenesis. Cell, 147, 1233-1247. [Google Scholar] [CrossRef] [PubMed]
|
|
[22]
|
Bonavita, E., Gentile, S., Rubino, M., Maina, V., Papait, R., Kunderfranco, P., et al. (2015) PTX3 Is an Extrinsic Oncosuppressor Regulating Complement-Dependent Inflammation in Cancer. Cell, 160, 700-714. [Google Scholar] [CrossRef] [PubMed]
|
|
[23]
|
Rava, M., D’Andrea, A., Doni, M., Kress, T.R., Ostuni, R., Bianchi, V., et al. (2017) Mutual Epithelium-Macrophage Dependency in Liver Carcinogenesis Mediated by ST18. Hepatology (Baltimore, Md), 65, 1708-1719. [Google Scholar] [CrossRef] [PubMed]
|
|
[24]
|
Wang, D., Yang, L., Yue, D., Cao, L., Li, L., Wang, D., et al. (2019) Macrophage-Derived CCL22 Promotes an Immunosuppressive Tumor Microenvironment via IL-8 in Malignant Pleural Effusion. Cancer Letters, 452, 244-253. [Google Scholar] [CrossRef] [PubMed]
|
|
[25]
|
Yin, C., Evason, K.J., Asahina, K. and Stainier, D.Y.R. (2013) Hepatic Stellate Cells in Liver Development, Regeneration, and Cancer. Journal of Clinical Investigation, 123, 1902-1910. [Google Scholar] [CrossRef]
|
|
[26]
|
Chen, Y., Choi, S.S., Michelotti, G.A., Chan, I.S., Swiderska-Syn, M., Karaca, G.F., et al. (2012) Hedgehog Controls Hepatic Stellate Cell Fate by Regulating Metabolism. Gastroenterology, 143, 1319-1329. [Google Scholar] [CrossRef] [PubMed]
|
|
[27]
|
Maeda, S., Kamata, H., Luo, J.L., Leffert, H. and Karin, M. (2005) IKKβ Couples Hepatocyte Death to Cytokine-Driven Compensatory Proliferation That Promotes Chemical Hepatocarcinogenesis. Cell, 121, 977-990. [Google Scholar] [CrossRef] [PubMed]
|
|
[28]
|
Maed, S., Hikiba, Y., Sakamoto, K., Nakagawa, H., Hirata, Y., Hayakawa, Y., Yanai, A., Ogura, K., Karin, M. and Omata, M. (2009) I Kappa B Kinase Beta/Nuclear Factor-kappaB Activation Controls the Development of Liver Metastasis by Way of Interleukin-6 Expression. Hepatology, 50, 1851-1860. [Google Scholar] [CrossRef] [PubMed]
|
|
[29]
|
Taub, R. (2003) Hepatoprotection via the IL-6/Stat3 Pathway. Journal of Clinical Investigation, 112, 978-980. [Google Scholar] [CrossRef]
|
|
[30]
|
Van Hees, S., Michielsen, P. and Vanwolleghem, T. (2016) Circulating Predictive and Diagnostic Biomarkers for Hepatitis B Virus-Associated Hepatocellular Carcinoma. World Journal of Gastroenterology, 22, 8271. [Google Scholar] [CrossRef] [PubMed]
|
|
[31]
|
Kao, J.-T., Feng, C.-L., Yu, C.-J., Tsai, S.-M., Hsu, P.-N., Chen, Y.-L. and Wu, Y.-Y. (2015) IL-6, through p-STAT3 Rather than p-STAT1, Activates Hepatocarcinogenesis and Affects the Survival of Hepatocellular Carcinoma Patients: A Cohort Study. BMC Gastroenterology, 15, 50. [Google Scholar] [CrossRef] [PubMed]
|
|
[32]
|
He, G., Yu, G.-Y., Temkin, V., Ogata, H., Kuntzen, C., Sakurai, T., Sieghart, W., Peck-Radosavljevic, M., Leffert, H.L. and Karin, M. (2010) Hepatocyte IKKβ/NF-κB Inhibits Tumor Promotion and Progression by Preventing Oxidative Stress-Driven STAT3 Activation. Cancer Cell, 17, 286-297. [Google Scholar] [CrossRef] [PubMed]
|
|
[33]
|
Rebouissou, S., Amessou, M., Couchy, G., Poussin, K., Imbeaud, S., Pilati, C., Izard, T., Balabaud, C., Bioulac-Sage, P. and Zucman-Rossi, J. (2009) Frequent In-Frame Somatic Deletions Activate gp130 in Inflammatory Hepatocellular Tumors. Nature, 457, 200. [Google Scholar] [CrossRef] [PubMed]
|
|
[34]
|
Kusaba, M., Nakao, K., Goto, T., Nishimura, D., Kawashima, H., Shibata, H., Motoyoshi, Y., Taura, N., Ichikawa, T. and Hamasaki, K. (2007) Abrogation of Constitutive STAT3 Activity Sensitizes Human Hepatoma Cells to TRAIL-Mediated Apoptosis. Journal of Hepatology, 47, 546-555. [Google Scholar] [CrossRef] [PubMed]
|
|
[35]
|
Jiang, R., Tan, Z., Deng, L., Chen, Y., Xia, Y., Gao, Y., Wang, X. and Sun, B. (2011) Interleukin-22 Promotes Human Hepatocellular Carcinoma by Activation of STAT3. Hepatology, 54, 900-909. [Google Scholar] [CrossRef] [PubMed]
|
|
[36]
|
Mercer, T.R., Dinger, M.E. and Mattick, J.S. (2009) Long Non-Coding RNAs: Insights into Functions. Nature Reviews Genetics, 10, 155. [Google Scholar] [CrossRef] [PubMed]
|
|
[37]
|
Cheng, C.J., Bahal, R., Babar, I.A., Pincus, Z., Barrera, F., Liu, C., et al. (2015) MicroRNA Silencing for Cancer Therapy Is Targeted to the Tumor Microenvironment. Nature, 518, 107-110. [Google Scholar] [CrossRef] [PubMed]
|
|
[38]
|
Zhou, D., Huang, C., Lin, Z., et al. (2014) Macrophage Polarization and Function Emphasize the Evolving Roles of Coordinated Regulation of Cellular Signaling Pathways. Cell Signal, 26, 192-197. [Google Scholar] [CrossRef] [PubMed]
|
|
[39]
|
Zhang, N., Duan, W.D., Leng, J.J., Zhou, L., Wang, X., Xu, Y.Z., Wang, X.D., Zhang, A.Q. and Dong, J.H. (2015) STAT3 Regulates the Migration and Invasion of a Stem-Like Subpopulation through microRNA-21 and Multiple Targets in Hepatocellular Carcinoma. Oncology Reports, 33, 1493-1498. [Google Scholar] [CrossRef] [PubMed]
|
|
[40]
|
Wang, B., Majumder, S., Nuovo, G., Kutay, H., Olivia, S., Patel, T., Schmittgen, T.D., Croce, C., Ghoshal, K. and Jacob, S.T. (2009) Role of microRNA-155 at Early Stages of Hepatocarcinogenesis Induced by Choline-Deficient and Amino Acid-Defined Diet in C57BL/6 Mice. Hepatology, 50, 1152-1161. [Google Scholar] [CrossRef] [PubMed]
|
|
[41]
|
Li, X.Q., Ren, Z.X., Li, K., Huang, J.J., Huang, Z.T., Zhou, T.R., Cao, H.Y., Zhang, F.X. and Tan, B. (2018) Key Anti-Fibrosis Associated Long Noncoding RNAs Identified in Human Hepatic Stellate Cell via Transcriptome Sequencing Analysis. International Journal of Molecular Sciences, 19, 675. [Google Scholar] [CrossRef] [PubMed]
|
|
[42]
|
Ye, Y., Xu, Y., Lai, Y., et al. (2018) Long Noncoding RNA Cox-2 Prevents Immune Evasion and Metastasis of Hepatocellular Carcinoma by Altering M1/M2 Macrophage Polarization. Journal of Cellular Biochemistry, 119, 2951-2963. [Google Scholar] [CrossRef] [PubMed]
|
|
[43]
|
Marquardt, J.U. (2018) The Role of Transforming Growth Factor-beta in Human Hepatocarcinogenesis: Mechanistic and Therapeutic Implications from an Integrative Multiomics Approach. Gastroenterology, 154, 17-20. [Google Scholar] [CrossRef] [PubMed]
|
|
[44]
|
Merdrignac, A., Angenard, G., Allain, C., Petitjean, K., Berget, D., Bellaud, P., Fautrel, A., Turlin, B., Clement, B., Dooley, S., et al. (2018) A Novel Transforming Growth Factor Beta-Induced Long Noncoding RNA Promotes an Inflammatory Microenvironment in Human Intrahepatic Cholangiocarcinoma. Hepatology Communications, 2, 254-269. [Google Scholar] [CrossRef] [PubMed]
|
|
[45]
|
Yuan, J.H., Yang, F., Wang, F., Ma, J.Z., Guo, Y.J., Tao, Q.F., Liu, F., Pan, W., Wang, T.T., Zhou, C.C., et al. (2014) A Long Noncoding RNA Activated by TGF-beta Promotes the Invasion-Metastasis Cascade in Hepatocellular Carcinoma. Cancer Cell, 25, 666-681. [Google Scholar] [CrossRef] [PubMed]
|
|
[46]
|
Almajhdi, F.N., Al-Quadri, A.Y. and Hussain, Z. (2013) Differential Expression of Transforming Growth Factor-beta1 and HBx Enhances Hepatitis B Virus Replication and Augments Host Immune Cytokines and Chemokines. Annals of Hepatology, 12, 408-415. [Google Scholar] [CrossRef]
|
|
[47]
|
Xiang, W.Q., Feng, W.F., Ke, W., Sun, Z., Chen, Z. and Liu, W. (2011) Hepatitis B Virus X Protein Stimulates IL-6 Expression in Hepatocytes via a MyD88-Dependent Pathway. Journal of Hepatology, 54, 26-33. [Google Scholar] [CrossRef] [PubMed]
|
|
[48]
|
Sheng, T., Wang, B., Deng, B., Qu, L., Qi, X.S., Wang, X.L., Deng, G.L. and Sun, X. (2015) The Relationship between Serum Interleukin-6 and the Recurrence of Hepatitis b Virus-Related Hepatocellular Carcinoma after Curative Resection. Medicine (Baltimore), 94, e941. [Google Scholar] [CrossRef]
|
|
[49]
|
Xia, L., Tian, D., Huang, W., Zhu, H., Wang, J., Zhang, Y., Hu, H., Nie, Y., Fan, D. and Wu, K. (2012) Upregulation of IL-23 Expression in Patients with Chronic Hepatitis B Is Mediated by the HBx/ERK/NF-kB Pathway. The Journal of Immunology, 188, 753-764. [Google Scholar] [CrossRef] [PubMed]
|
|
[50]
|
Wang, D., Zou, L., Liu, X., Zhu, H. and Zhu, R. (2016) Chemokine Expression Profiles of Human Hepatoma Cell Lines Mediated by Hepatitis b Virus x Protein. Pathology and Oncology Research, 22, 393-399. [Google Scholar] [CrossRef] [PubMed]
|
|
[51]
|
Tangkijvanich, P., Thong-Ngam, D., Mahachai, V., Theamboonlers, A. and Poovorawan, Y. (2007) Role of Serum Interleukin-18 as a Prognostic Factor in Patients with Hepatocellular Carcinoma. World Journal of Gastroenterology, 13, 4345-4349. [Google Scholar] [CrossRef] [PubMed]
|
|
[52]
|
Liu, K.G., Shao, X.L., Xie, H.H., Xu, L., Zhao, H., Guo, Z.H., Li, L. and Liu, J. (2010) The Expression of Hepatitis B Virus X Protein and Cyclooxygenase-2 in Hepatitis B Virus-Related Hepatocellular Carcinoma: Correlation with Microangiogenesis and Metastasis, and What Is the Possible Mechanism. Chinese Journal of Hepatology, 18, 831-836.
|
|
[53]
|
Zheng, B.Y., Fang, X.F., Zou, L.Y., Huang, Y.H., Chen, Z.X., Li, D., Zhou, L.Y., Chen, H. and Wang, X.Z. (2014) The Co-Localization of HBx and COXIII Upregulates COX-2 Promoting HepG2 Cell Growth. International Journal of Oncology, 45, 1143-1150. [Google Scholar] [CrossRef] [PubMed]
|
|
[54]
|
Yang, Z.F. and Poon, R.T. (2008) Vascular Changes in Hepatocellular Carcinoma. The Anatomical Record (Hoboken), 291, 721-734. [Google Scholar] [CrossRef] [PubMed]
|
|
[55]
|
Yu, D., Sun, X., Qiu, Y., et al. (2007) Identification and Clinical Significance of Mobilized Endothelial Progenitor Cells in Tumor Vasculogenesis of Hepatocellular Carcinoma. Clinical Cancer Research, 13, 3814-3824. [Google Scholar] [CrossRef]
|
|
[56]
|
Itano, N., Zhuo, L. and Kimata, K. (2008) Impact of the Hyaluronan-Rich Tumor Microenvironment on Cancer Initiation and Progression. Cancer Science, 99, 1720-1725. [Google Scholar] [CrossRef] [PubMed]
|
|
[57]
|
Lewis, C.E. and Pollard, J.W. (2006) Distinct Role of Macrophages in Different Tumor Microenvironments. Cancer Research, 66, 605-612. [Google Scholar] [CrossRef]
|
|
[58]
|
Song, G., Ohashi, T., Sakamoto, N. and Sato, M. (2006) Adhesive Force of Human Hepatoma HepG2 Cells to Endothelial Cells and Expression of E-Selectin. Molecular and Cellular Biomechanics, 3, 61-68.
|
|
[59]
|
Liu, L., Zhu, X.D., Wang, W.Q., et al. (2010) Activation of Beta-Catenin by Hypoxia in Hepatocellular Carcinoma Contributes to Enhanced Metastatic Potential and Poor Prognosis. Clinical Cancer Research, 16, 2740-2750. [Google Scholar] [CrossRef]
|
|
[60]
|
Polyak, K. and Weinberg, R.A. (2009) Transitions between Epithelial and Mesenchymal States: Acquisition of Malignant and Stem Cell Traits. Nature Reviews Cancer, 9, 265-273. [Google Scholar] [CrossRef] [PubMed]
|
|
[61]
|
Ren, T., Zhu, L. and Cheng, M. (2017) CXCL10 Accelerates EMT and Metastasis by MMP-2 in Hepatocellular Carcinoma. American Journal of Translational Research, 9, 2824-2837.
|
|
[62]
|
Cui, X., Li, Z., Gao, J., Gao, P.J., Ni, Y.B. and Zhu, J.Y. (2016) Elevated CXCL1 Increases Hepatocellular Carcinoma Aggressiveness and Is Inhibited by miRNA-200a. Oncotarget, 7, 65052-65066. [Google Scholar] [CrossRef] [PubMed]
|
|
[63]
|
Lin, H., Yang, B. and Teng, M. (2017) T-Cell Immunoglobulin Mucin-3 as a Potential Inducer of the Epithelial-Mesenchymal Transition in Hepatocellular Carcinoma. Oncology Letters, 14, 5899-5905. [Google Scholar] [CrossRef] [PubMed]
|
|
[64]
|
Liu, Y., Liu, Y., Yan, X., Xu, Y., Luo, F., Ye, J., Yan, H., Yang, X., Huang, X., Zhang, J., et al. (2014) HIFs Enhance the Migratory and Neoplastic Capacities of Hepatocellular Carcinoma Cells by Promoting EMT. Tumor Biology, 35, 8103-8114. [Google Scholar] [CrossRef] [PubMed]
|
|
[65]
|
Wang, Z., Luo, L., Cheng, Y., et al. (2018) Correlation between Postoperative Early Recurrence of Hepatocellular Carcinoma and Mesenchymal Circulating Tumor Cells in Peripheral Blood. Journal of Gastrointestinal Surgery, 22, 633-639. [Google Scholar] [CrossRef] [PubMed]
|
|
[66]
|
Castven, D., Czauderna, C. and Marquardt, J.U. (2017) Contribution of the Cancer Stem Cell Phenotype to Hepatocellular Carcinoma Resistance. In: Villanueva, A., Ed., Resistance to Molecular Therapies for Hepatocellular Carcinoma, Springer International Publishing, Cham, Volume 13, 65-91. [Google Scholar] [CrossRef]
|
|
[67]
|
Nowak, M.A., Bonhoeffer, S., Hill, A.M., Boehme, R., Thomas, H.C. and McDade, H. (1996) Viral Dynamics in Hepatitis B Virus Infection. Proceedings of the National Academy of Sciences of the United States of America, 93, 4398. [Google Scholar] [CrossRef] [PubMed]
|
|
[68]
|
Junttila, M.R. and de Sauvage, F.J. (2013) Influence of Tumor Micro-Environment Heterogeneity on Therapeutic Response. Nature, 501, 346-354. [Google Scholar] [CrossRef] [PubMed]
|
|
[69]
|
Iliopoulos, D., Hirsch, H.A., Wang, G. and Struhl, K. (2011) Inducible Formation of Breast Cancer Stem Cells and Their Dynamic Equilibrium with Non-Stem Cancer Cells via IL6 Secretion. Proceedings of the National Academy of Sciences of the United States of America, 108, 1397. [Google Scholar] [CrossRef] [PubMed]
|
|
[70]
|
Tsuda, A., Chow, A., Wu, J., Somlo, G., Chu, P., Loera, S., Luu, T., Li, A.X., Wu, X., Ye, W., et al. (2012) CCL2 Mediates Crosstalk between Cancer Cells and Stromal Fibroblasts That Regulates Breast Cancer Stem Cells. Cancer Research, 72, 2768. [Google Scholar] [CrossRef]
|
|
[71]
|
Todaro, M., Gaggianesi, M., Catalano, V., Benfante, A., Iovino, F., Biffoni, M., Apuzzo, T., Sperduti, I., Volpe, S., Cocorullo, G., et al. (2014) CD44v6 Is a Marker of Constitutive and Reprogrammed Cancer Stem Cells Driving Colon Cancer Metastasis. Cell Stem Cell, 14, 342-356. [Google Scholar] [CrossRef] [PubMed]
|
|
[72]
|
Cui, Y., Sun, S., Ren, K., Quan, M., Song, Z., Zou, H., Li, D. and Cao, J. (2016) Reversal of Liver Cancer-Associated Stellate Cell-Induced Stem-Like Characteristics in SMMC-7721 Cells by 8-Bromo-7-methoxy Chrysin via Inhibiting STAT3 Activation. Oncology Reports, 35, 2952-2962. [Google Scholar] [CrossRef] [PubMed]
|
|
[73]
|
Chen, A., Xu, C., Luo, Y., Liu, L., Song, K., Deng, G., Yang, M., Cao, J., Yuan, L. and Li, X. (2019) Disruption of Crosstalk between LX-2 and Liver Cancer Stem-Like Cells from MHCC97H Cells by DFOG via Inhibiting FOXM1. Acta Biochimica et Biophysica Sinica, 51, 1267-1275. [Google Scholar] [CrossRef] [PubMed]
|
|
[74]
|
Sica, A., Porta, C., Amadori, A. and Pastò, A. (2017) Tumor-Associated Myeloid Cells as Guiding Forces of Cancer Cell Stemness. Cancer Immunology, Immunotherapy, 66, 1025-1036. [Google Scholar] [CrossRef] [PubMed]
|
|
[75]
|
Otvos, B., Silver, D.J., Mulkearns-Hubert, E.E., Alvarado, A.G., Turaga, S.M., Sorensen, M.D., Rayman, P., Flavahan, W.A., Hale, J.S., Stoltz, K., et al. (2016) Cancer Stem Cell-Secreted Macrophage Migration Inhibitory Factor Stimulates Myeloid-Derived Suppressor Cell Function and Facilitates Glioblastoma Immune Evasion. Stem Cells, 34, 2026-2039. [Google Scholar] [CrossRef] [PubMed]
|
|
[76]
|
Chang, T.-S., Chen, C.-L., Wu, Y.-C., Liu, J.-J., Kuo, Y.C., Lee, K.-F., Lin, S.-Y., Lin, S.-E., Tung, S.-Y., Kuo, L.-M., et al. (2016) Inflammation Promotes Expression of Stemness-Related Properties in HBV-Related Hepatocellular Carcinoma. PLoS ONE, 11, e0149897. [Google Scholar] [CrossRef] [PubMed]
|
|
[77]
|
Ng, K.-Y., Chai, S., Tong, M., Guan, X.-Y., Lin, C.-H., Ching, Y.-P., Xie, D., Cheng, A.S.-L. and Ma, S. (2016) C-Terminal Truncated Hepatitis B Virus X Protein Promotes Hepatocellular Carcinogenesis through Induction of Cancer and Stem Cell-Like Properties. Oncotarget, 7, 24005-24017. [Google Scholar] [CrossRef] [PubMed]
|
|
[78]
|
Liu, Z., Dai, X., Wang, T., Zhang, C., Zhang, W., Zhang, W., Zhang, Q., Wu, K., Liu, F., Liu, Y., et al. (2017) Hepatitis B Virus PreS1 Facilitates Hepatocellular Carcinoma Development by Promoting Appearance and Self-Renewal of Liver Cancer Stem Cells. Cancer Letters, 400, 149-160. [Google Scholar] [CrossRef] [PubMed]
|
|
[79]
|
Shirasaki, T., Honda, M., Yamashita, T., Nio, K., Shimakami, T., Shimizu, R., Nakasyo, S., Murai, K., Shirasaki, N., Okada, H., et al. (2018) The Osteopontin-CD44 Axis in Hepatic Cancer Stem Cells Regulates IFN Signaling and HCV Replication. Scientific Reports, 8, Article No. 13143. [Google Scholar] [CrossRef] [PubMed]
|
|
[80]
|
Liu, H., Zhang, W., Jia, Y., Yu, Q., Grau, G.E., Peng, L., Ran, Y., Yang, Z., Deng, H. and Lou, J. (2013) Single-Cell Clones of Liver Cancer Stem Cells Have the Potential of Differentiating into Different Types of Tumor Cells. Cell Death & Disease, 4, e857. [Google Scholar] [CrossRef] [PubMed]
|
|
[81]
|
Sukowati, C.H., Anfuso, B., Croce, L.S. and Tiribelli, C. (2015) The Role of Multipotent Cancer-Associated Fibroblasts in Hepatocarcinogenesis. BMC Cancer, 15, 188. [Google Scholar] [CrossRef] [PubMed]
|
|
[82]
|
Wan, S., Zhao, E., Kryczek, I., Vatan, L., Sadovskaya, A., Ludema, G., Simeone, D.M., Zou, W. and Welling, T.H. (2014) Tumor-Associated Macrophages Produce Interleukin Six and Signal via STAT3 to Promote the Expansion of Human Hepatocellular Carcinoma Stem Cells. Gastroenterology, 147, 1393-1404. [Google Scholar] [CrossRef] [PubMed]
|
|
[83]
|
Marquardt, J.U., Gomez-Quiroz, L., Arreguin Camacho, L.O., Pinna, F., Lee, Y.H., Kitade, M., Dominguez, M.P., Castven, D., Breuhahn, K., Conner, E.A., et al. (2015) Curcumin Effectively Inhibits Oncogenic NF-kappaB Signaling and Restrains Stemness Features in Liver Cancer. Journal of Hepatology, 63, 661-669. [Google Scholar] [CrossRef] [PubMed]
|
|
[84]
|
You, N., Zheng, L., Liu, W., Zhong, X., Wang, W. and Li, J. (2014) Proliferation Inhibition and Differentiation Induction of Hepatic Cancer Stem Cells by Knockdown of BC047440: A Potential Therapeutic Target of Stem Cell Treatment for Hepatocellular Carcinoma. Oncology Reports, 31, 1911-1920. [Google Scholar] [CrossRef] [PubMed]
|