血清IgE在哮喘和慢性阻塞性肺疾病进展中的作用
The Role of IgE in COPD and Asthma
DOI: 10.12677/ACM.2021.1110698, PDF,   
作者: 刘 健：海军军医大学第一附属医院(上海长海医院)，上海
关键词: COPD；哮喘；IgE；特应性；过敏；COPD； Asthma； IgE； Atopy； Allergy
摘要: 哮喘和慢性阻塞性肺疾病(chronic obstructive pulmonary disease, COPD)是两种常见的、以慢性气道炎症为主要特征的呼吸系统疾病。相关研究发现，IgE (immunoglobulin E)在哮喘和COPD的疾病进展中都起着重要作用，因为它与两种疾病的呼吸道症状、肺功能、细菌和病毒感染、气道重塑和支气管反应性相关。本文通过对相关研究的整理，分析IgE (包括特异性IgE和总IgE)在COPD和哮喘中的作用，探寻两种疾病在治疗方式上的异同。
Abstract: Asthma and chronic obstructive pulmonary disease (COPD) are two prevalent chronic airway inflammatory diseases. IgE production appears to play an important role in the development of both COPD and asthma, as it has been associated with respiratory symptoms, lung function, bacterial and viral infections, airway remodeling and bronchial hyperreactivity in both diseases. The aim of this review is to summarize all current data concerning the role of specific and total IgE in COPD and asthma and to highlight similarities and differences in view of possible therapeutic interventions.
文章引用：刘健. 血清IgE在哮喘和慢性阻塞性肺疾病进展中的作用[J]. 临床医学进展, 2021, 11(10): 4751-4757. https://doi.org/10.12677/ACM.2021.1110698

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