浅谈胆囊结石的成因及预防
Discussion on the Cause and Prevention of Gallstone
DOI: 10.12677/ACM.2021.1111710, PDF,   
作者: 冶占明, 徐 贺：青海大学研究生院，肝胆胰外科，青海 西宁；樊海宁*：青海大学附属医院，肝胆胰外科，青海 西宁
关键词: 胆囊结石；流行病学；病因；分析；Gallstone； Epidemiology； The Cause； Analysis
摘要: 胆囊结石是我国的常见病与多发病。我国胆石病的种类和发病率随着人民生活水平的提高也出现了很大的变化。其成因非常复杂，与多种因素有关，任何影响胆固醇与胆汁酸和磷脂浓度比例和造成胆汁瘀滞的因素都能导致结石形成。
Abstract: Gallstone is a common and frequently-occurring disease in China. The types and incidence of cholelithiasis in China have changed greatly with the improvement of people’s living standards. The cause of calculi is very complicated and related to many factors. Any factor that affects the ratio of cholesterol to bile acid and phospholipid concentration and causes bile stasis can lead to the formation of calculi.
文章引用：冶占明, 徐贺, 樊海宁. 浅谈胆囊结石的成因及预防[J]. 临床医学进展, 2021, 11(11): 4846-4850. https://doi.org/10.12677/ACM.2021.1111710

参考文献

[1] European Association for the Study of the Liver (EASL) (2016) EASL Clinical Practice Guidelines on the Prevention, Diagnosis and Treatment of Gallstones. Journal of Hepatology, 65, 146-181. [Google Scholar] [CrossRef] [PubMed]
[2] 力毛措. 牧区胆结石患病率调查与原因分析[J]. 中国民族医药杂志, 2012, 32(6): 72-73.
[3] Shabanzadeh, D.M., Sørensen, L.T. and Jørgensen, T. (2016) A Prediction Rule for Risk Stratification of Incidentally Discovered Gallstones: Results from a Large Cohort Study. Gastroenterology, 150, 156-167.e1. [Google Scholar] [CrossRef] [PubMed]
[4] Sieron, D., Czerny, B., Sieron-Stoltny, K., et al. (2016) The Effect of Chronic Estrogen Application on Bile and Gallstone Composition in Women with Cholelithiasis. Minerva Endocrinology, 41, 19-27.
[5] Simonsen, M.H., Erichsen, R., Frøslev, T., et al. (2013) Postmenopausal Estrogen Therapy and Risk of Gallstone Disease: A Population-Based Case-Control Study. Drug Safety, 36, 1189-1197. [Google Scholar] [CrossRef] [PubMed]
[6] Lammert, F., Gurusamy, K., Ko, C.W., et al. (2016) Gallstones. Nature Reviews Disease Primers, 2, 16024. [Google Scholar] [CrossRef] [PubMed]
[7] Wang, H.H., Afdhal, N.H. and Wang, D.Q.H. (2004) Estrogen Receptor α, But Not β, Plays a Major Role in 17 β-Estradiol-Induced Murine Cholesterol Gallstones. Gastroenterology, 127, 239-249. [Google Scholar] [CrossRef] [PubMed]
[8] Saha, P., Shumate, J.L., Caldwell, J.G., et al. (2020) Inter-Domain Dynamics Drive Cholesterol Transport by NPC1 and NPC1L1 Proteins. Elife, 9, e57089. [Google Scholar] [CrossRef] 
[9] de Bari, O., Wang, H.H., Portincasa, P., et al. (2014) Ezetimibe Prevents the Formation of Oestrogen-Induced Cholesterol Gallstones in Mice. European Journal of Clinical Investigation, 44, 1159-1168. [Google Scholar] [CrossRef] [PubMed]
[10] Ansarimoghaddam, A., Adineh, H.A., Zareban, I., et al. (2018) Prevalence of Metabolic Syndrome in Middle-East Countries: Meta-Analysis of Cross-Sectional Studies. Diabetology & Metabolic Syndrome, 12, 195-201. [Google Scholar] [CrossRef] [PubMed]
[11] 韩晓月, 薛荣泉, 夏医君, 等. 胆道结石动物模型的研究进展[J/CD]. 中华损伤与修复杂志(电子版), 2017, 12(6): 470-472.
[12] Lei, Z.M., Ye, M.X., Fu, W.G., et al. (2008) Levels of Serum Leptin, Chole-Cystokinin, Plasma Lipid and Lipoprotein Differ between Patients with Gallstone or/and Those with Hepatolithiasis. Hepatobiliary & Pancreatic Diseases International, 7, 65-69.
[13] Saracs, S., et al. (2015) Leptin Levels and Lipoprotein Profiles in Patients with Cholelithiasis. Journal of International Medical Research, 43, 385-392. [Google Scholar] [CrossRef] [PubMed]
[14] 辜天慧. 242例胆道手术患者胆汁成分与胆石成因研究[J]. 川北医学院学报, 2016, 31(6): 838-840.
[15] 希龙夫, 薛荣泉, 夏医君, 等. 瘦素在胆囊胆固醇结石形成中的作用[J]. 国际外科学杂志, 2017, 44(6): 383-387.
[16] 梁明杨, 魏垚臣, 王一鸣, 等. 空腹血糖水平与胆石症发病风险的关系[J]. 临床肝胆病杂志, 2019, 35(11): 2517-2522.
[17] 谢经丰, 王永芹,, 袁晟光. 胆汁酸与肠道菌群及其相互影响在肝再生中的作用研究进展[J]. 肝胆胰外科杂志, 2018, 30(1): 87-88.
[18] 邓太平, 李砚. 胆石症与肠道菌群的相关性临床分析[J]. 西北国防医学杂志, 2017, 38(5): 54-56.
[19] 杜耀, 李卫平, 熊辉, 等. 保留幽门胃切除术治疗早期胃中部癌有效性和安全性的Meta分析[J]. 中华胃肠外科杂志, 2020, 23(11): 1088-1096.
[20] 张天一, 王勇. 减重手术后新发胆囊结石的成因及对策[J]. 中华消化外科杂志, 2019(9): 893-896.
[21] 梁法生, 张博, 兰云霞, 梁杰, 丁洁. 胆囊形态折叠与胆囊结石的关系[J]. 世界华人消化杂志, 2016, 24(15): 2390-2393.

为你推荐