外泌体在乳腺癌侵袭转移及治疗耐药中的研究进展
Research Progress of Exosome in Invasion, Metastasis and Drug Resistance of Breast Cancer
DOI: 10.12677/ACM.2021.1111711, PDF,   
作者: 阚宝芹, 王晓武:青海大学附属医院乳腺甲状腺外科,青海 西宁
关键词: 乳腺癌外泌体侵袭转移化疗耐药进展Breast Cancer Exosome Invasion and Metastasis Chemotherapy Resistance Progress
摘要: 研究提示外泌体通过分泌各种信号分子参与乳腺癌发展及治疗过程,乳腺癌在侵袭转移过程中缺乏可重复性高且可靠的特异性肿瘤标志物,治疗上仍受药物毒性、治疗耐药等因素的限制,故外泌体成为进一步突破乳腺癌侵袭转移及治疗耐药研究的新靶标。笔者在本文中对外泌体与乳腺癌侵袭转移及治疗耐药研究进展做一综述,探讨其在乳腺癌诊治中的意义。
Abstract: It is suggested that exosome is involved in the development and treatment of breast cancer by secreting various signal molecules. In the process of invasion and metastasis, breast cancer lacks high reproducible and reliable specific tumor markers. The treatment is still limited by drug toxicity and drug resistance. Therefore, exosome has become a new target for further breakthrough in breast cancer invasion and metastasis and drug resistance. In this article, we reviewed the progress of invasion and metastasis of breast cancer and drug resistance, and discussed its significance in the diagnosis and treatment of breast cancer.
文章引用:阚宝芹, 王晓武. 外泌体在乳腺癌侵袭转移及治疗耐药中的研究进展[J]. 临床医学进展, 2021, 11(11): 4851-4855. https://doi.org/10.12677/ACM.2021.1111711

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