关于导电材料在组织工程中应用的研究
Research on the Application of Conductive Materials in Tissue Engineering
DOI: 10.12677/NAT.2021.114030, PDF,   
作者: 徐志新, 赵亚红*, 杨宇民*：南通大学，教育部/江苏省神经再生重点实验室/神经再生协同创新中心，江苏 南通
关键词: 组织工程；导电材料；生物相容性；聚合物； Tissue Engineering； Conductive Materials； Bio-compatibility； Polymers
摘要: 组织工程学一直致力于将生物细胞与材料相结合，体外或体内构建器官组织用于修复人类身体的损伤。随着研究的不断深入，支架材料也不断地仿生化、功能化，能够通过改善细胞的活性来修复或调节功能受损的组织。研究显示细胞活动与细胞内信号传导多以生物电信号的形式进行，因而导电材料可以赋予损伤组织更加良好的生物传感环境，有助于引导细胞在损伤部位的行为，包括迁移、粘附、增殖和分化。从聚合物到复合材料，再到陶瓷甚至金属，已经有各种类型的导电材料被引入组织工程中，根据其导电性能也可划分为导电与半导电。本综述旨在重点介绍并总结那些应用于组织工程中的导电生物材料的研究进展。
Abstract: Tissue engineering has been committed to combining biological cells and materials to construct organs and tissues in vitro or in vivo to repair human body damage. With the deepening of research, scaffold materials are constantly biomimetic and functionalized, and can repair or mediate damaged tissues by improving cell activity. Studies have shown that cell activities and intracellular signal transduction are mostly carried out in the form of bioelectrical signals. Therefore, conductive materials can give damaged tissues a better biosensing environment and help guide cell behavior at the damaged site, including migration, adhesion, proliferation and differentiation. From polymers to composite materials, to ceramics and even metals, various types of conductive materials have been introduced into tissue engineering. According to their conductive properties, they can also be divided into conductive and semi-conductive. This review aims to introduce and summarize the research progress of conductive biomaterials used in tissue engineering.
文章引用：徐志新, 赵亚红, 杨宇民. 关于导电材料在组织工程中应用的研究[J]. 纳米技术, 2021, 11(4): 278-287. https://doi.org/10.12677/NAT.2021.114030

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