局部晚期宫颈癌的治疗现状

Treatment Status of Locally Advanced Cervical Cancer

摘要: 目前宫颈癌治疗主要采用手术治疗、体外照射、近距离放射治疗、化学药物治疗等，除此以外靶向及免疫治疗也在研究发展中。国际妇产科联盟将局部晚期宫颈癌(Locally Advanced Cervical Cancer, LACC)分为狭义及广义，狭义局部晚期宫颈癌是指肿瘤未发生远处转移但癌灶直径等于或超过4 cm，主要是指IB3和IIA2期(FIGO分期2018版)宫颈癌；广义局部晚期宫颈癌包括IB2-IVA期的宫颈癌。本文所讨论的局部晚期宫颈癌主要是狭义局部晚期宫颈癌。目前针对局部晚期宫颈癌的治疗方法多样，均在不同程度上提高局部晚期宫颈癌的治愈率及患者生活质量，但仍在世界范围内尚未达成共识。所以本文主要就局部晚期宫颈癌的治疗现状展开论述。

Abstract: At present, the treatment of cervical cancer mainly adopts surgical treatment, external irradiation, brachytherapy, chemotherapeutic therapy, etc. In addition, targeted and immunotherapy are also under development. The International Union of Obstetrics and Gynecology divides Locally Advanced Cervical Cancer (LACC) into narrow sense and broad sense. Narrow sense refers to Locally Advanced Cervical Cancer that has no distant metastasis but has a tumor diameter that equals to or greater than 4 cm, which mainly refers to IB3 and IIA2 cervical cancer (FIGO stage 2018 edition); generalized local advanced cervical cancer includes ib2-IVA stage cervical cancer. The local advanced cervical cancer discussed in this paper is mainly narrow local advanced cervical cancer. At present, there are various treatments for locally advanced cervical cancer, all of which can improve the cure rate and the quality of life of patients to varying degrees, but there is still no consensus in the world. Therefore, this article mainly discusses the treatment status of local advanced cervical cancer.