补体系统在2型糖尿病微血管病变中的研究进展
Research Progress of Complement System in Microangiopathy of Type 2 Diabetes Mellitus
DOI: 10.12677/ACM.2021.1111766, PDF,   
作者: 董琳琳：青海大学，青海 西宁；赵玲莉：青海大学附属医院检验科，青海 西宁
关键词: 2型糖尿病；糖尿病微血管病变；补体系统；Type 2 Diabetes Mellitus； Diabetic Microangiopathy； Complement System
摘要: 糖尿病微血管病变是严重影响糖尿病患者生命健康和生活质量的重要并发症。补体系统作为人体重要的免疫系统，在体内有着广泛的生物学作用，可介导免疫应答和炎症反应，其在糖尿病微血管病变的进展过程中也发挥着重要的作用。本文回顾了补体系统在2型糖尿病微血管病变的相关研究，探讨了其作用机制。以补体系统为靶点，开发新的生物标志物与治疗药物有望成为2型糖尿病微血管病变诊断与治疗的新策略。
Abstract: Diabetic microangiopathy is an important complication that seriously affects the life and health of diabetic patients and quality of life. As an important human immune system, complement system has a wide range of biological functions in vivo, which can mediate immune response and inflammatory response. It also plays an important role in the progression of diabetic microangiopathy. This article reviews the related studies of complement system in type 2 diabetic microangiopathy and discusses its mechanism. Targeting the complement system, the development of new biomarkers and therapeutic drugs is expected to be a new strategy for the diagnosis and treatment of type 2 diabetic microangiopathy.
文章引用：董琳琳, 赵玲莉. 补体系统在2型糖尿病微血管病变中的研究进展[J]. 临床医学进展, 2021, 11(11): 5190-5195. https://doi.org/10.12677/ACM.2021.1111766

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