自酸蚀粘接剂用于窝沟封闭的研究进展
Self-Etch Adhesives’ Effectiveness in the Performance of Pit and Fissure Sealants
DOI: 10.12677/ACM.2021.1111785, PDF,   
作者: 陈奕曈, 蒋文翔, 吴志芳, 胡济安*:浙江大学医学院附属口腔医院·浙江大学口腔医学院·浙江省口腔疾病临床医学研究中心·浙江省口腔生物医学研究重点实验室·浙江大学癌症研究院,浙江 杭州
关键词: 窝沟封闭剂牙齿粘接剂口腔预防医学Pit and Fissure Sealants Dental Cements Preventive Dentistry
摘要: 窝沟封闭是一种有效地预防龋病的方法,其中树脂类窝沟封闭剂应用最为广泛。但是对于一些配合度差、咽反射敏感、口底较浅以及唾液分泌旺盛的患者,树脂类窝沟封闭剂失败率较高。自酸蚀粘接系统可以简化临床步骤、降低技术敏感性、减少椅旁时间。但是由于自酸蚀粘接系统中底涂剂的酸性通常较弱,其能否代替传统的磷酸进行窝沟封闭前的酸蚀仍存在争议。本文拟对自酸蚀粘接剂在窝沟封闭中的应用效果做一综述。
Abstract: Pit and fissure sealant is an effective method for caries prevention. The most popular type of pit and fissure sealant is resin-based sealants (RBSs). However, for patients with poor compliance, shallow mouth or hypersalivation, RBSs are easy to fail. Self-etch adhesive systems have several advantages like eliminating the prior acid etching and rinsing steps, simplifying the application technique, and decreasing the chair time. Due to the relatively milder acidity of self-etch adhesives, however, whether it can be applied before sealants without acid etching is still unclear. This review aims to evaluate the effect of self-etch systems on clinical performance of dental sealants.
文章引用:陈奕曈, 蒋文翔, 吴志芳, 胡济安. 自酸蚀粘接剂用于窝沟封闭的研究进展[J]. 临床医学进展, 2021, 11(11): 5313-5321. https://doi.org/10.12677/ACM.2021.1111785

参考文献

[1] Hou, J., Gu, Y., Zhu, L., Hu, Y., Sun, M. and Xue, H. (2017) Systemic Review of the Prevention of Pit and Fissure Caries of Permanent Molars by Resin Sealants in Children in China. Journal of Investigative and Clinical Dentistry, 8, 1-7.
[Google Scholar] [CrossRef] [PubMed]
[2] Wright, J.T., Crall, J.J., Fontana, M., Gillette, E.J., Nový, B.B., Dhar, V., et al. (2016) Evidence-Based Clinical Practice Guideline for the Use of Pit-and-Fissure Sealants: A Report of the American Dental Association and the American Academy of Pediatric Dentistry. Journal of the American Dental Association, 147, 672-682.e12.
[Google Scholar] [CrossRef] [PubMed]
[3] Wright, J.T., Tampi, M.P., Graham, L., Estrich, C., Crall, J.J., Fontana, M., et al. (2016) Sealants for Preventing and Arresting Pit-and-Fissure Occlusal Caries in Primary and Permanent Molars. Pediatric Dentistry, 38, 282-308.
[4] Cvikl, B., Moritz, A. and Bekes, K. (2018) Pit and Fissure Sealants—A Comprehensive Review. Dentistry Journal, 6, 1-8.
[Google Scholar] [CrossRef] [PubMed]
[5] Wright, J.T., Crall, J.J., Fontana, M., et al. (2016) Evidence-Based Clinical Practice Guideline for the Use of Pit-and-Fissure Sealants. Pediatric Dentistry, 38, 120-136.
[6] Kühnisch, J., Bedir, A., Lo, Y.-F., Kessler, A., Lang, T., Mansmann, U., et al. (2020) Meta-Analysis of the Longevity of Commonly Used Pit and Fissure Sealant Materials. Dental Materials, 36, e158-e168.
[Google Scholar] [CrossRef] [PubMed]
[7] 武洁, 刘茜, 陈央兰, 等. 酸蚀对乳牙玻璃离子窝沟封闭微渗漏和微拉伸强度的比较研究[J]. 口腔医学, 2020, 40(11): 1021-1025.
[8] Sreedevi, A., Brizuela, M. and Mohamed, S. (2021) Pit and Fissure Sealants. StatPearls, Treasure Island.
https://www.ncbi.nlm.nih.gov/books/NBK448116
[9] Ahovuo-Saloranta, A., Forss, H., Walsh, T., Nordblad, A., Mäkelä, M. and Worthington, H.V. (2017) Pit and Fissure Sealants for Preventing Dental Decay in Permanent Teeth. The Cochrane Database of Systematic Reviews, 7, CD001830.
[Google Scholar] [CrossRef
[10] 刘鹏辉, 朱洪光, 李凯华, 等. 不同封闭材料对乳磨牙窝沟封闭边缘微渗漏影响的实验研究[J]. 临床口腔医学杂志, 2021, 37(4): 211-214.
[11] Papageorgiou, S.N., Dimitraki, D., Kotsanos, N., Bekes, K. and van Waes, H. (2017) Performance of Pit and Fissure Sealants According to Tooth Characteristics: A Systematic Review and Meta-Analysis. Journal of Dentistry, 66, 8-17.
[Google Scholar] [CrossRef] [PubMed]
[12] 林挺, 卢友光, 张梦驰, 等. 口腔唾液污染和窝沟处理方式对窝沟封闭剂微渗漏影响的研究[J]. 现代口腔医学杂志, 2019, 33(2): 120-122.
[13] Naaman, R., El-Housseiny, A.A. and Alamoudi, N. (2017) The Use of Pit and Fissure Sealants—A Literature Review. Dentistry Journal, 5, 34.
[Google Scholar] [CrossRef] [PubMed]
[14] Lam, P.P.Y., Sardana, D., Ekambaram, M., Lee, G.H.M. and Yiu, C.K.Y. (2020) Effectiveness of Pit and Fissure Sealants for Preventing and Arresting Occlusal Caries in Primary Molars: A Systematic Review and Meta-Analysis. Journal of Evidence Based Dental Practice, 20, Article ID: 101404.
[Google Scholar] [CrossRef] [PubMed]
[15] Attar, M.H., Abdallah, M.A., Alharthy, H.A. and El Meligy, O.A. (2021) Effect of Bonding Agent on Retention of Different Sealants: An in Vitro Study. Journal of Clinical Pediatric Dentistry, 45, 177-185.
[Google Scholar] [CrossRef] [PubMed]
[16] Maher, M.M., Elkashlan, H.I. and El-Housseiny, A.A. (2013) Effectiveness of a Self-Etching Adhesive on Sealant Retention in Primary Teeth. Pediatric Dentistry, 35, 351-354.
[17] 李文敏. 自酸蚀粘接剂在乳磨牙窝沟封闭中的应用[J]. 口腔医学研究, 2016, 32(7): 757-759.
[18] 蓝巧瑛, 罗祖凤, 刘峥, 等. 自酸蚀粘结剂对六龄牙窝沟封闭临床效果的影响[J]. 全科口腔医学电子杂志, 2018, 5(30): 41-43.
[19] 石镕嘉, 许良, 徐稳安. 窝沟封闭剂的研究现状与进展[J]. 口腔医学, 2020, 40(7): 660-663.
[20] 裴丽玲, 薛欣, 吕晶, 等. 三种窝沟封闭剂边缘微渗漏及抗压强度的体外对比研究[J]. 现代口腔医学杂志, 2019, 33(3): 154-157.
[21] Sadat Hosseinipour, Z., Heidari, A., Shahrabi, M. and Poorzandpoush, K. (2019) Microleakage of a Self-Adhesive Flowable Composite, a Self-Adhesive Fissure Sealant and a Conventional Fissure Sealant in Permanent Teeth with/without Saliva Contamination. Frontiers in Dentistry, 16, 239-247.
[Google Scholar] [CrossRef] [PubMed]
[22] Dean, J. (2021) McDonald and Avery’s Dentistry for the Child and Adolescent. 11th Edition, Elsevier, St. Louis, 177-184.
[23] Carrilho, E., Cardoso, M., Marques Ferreira, M., Marto, C.M., Paula, A. and Coelho, A.S. (2019) 10-MDP Based Dental Adhesives: Adhesive Interface Characterization and Adhesive Stability—A Systematic Review. Materials (Basel), 12, 790.
[Google Scholar] [CrossRef] [PubMed]
[24] Fehrenbach, J., Isolan, C.P. and Münchow, E.A. (2021) Is the Presence of 10-MDP Associated to Higher Bonding Performance for Self-Etching Adhesive Systems? A Meta-Analysis of in Vitro Studies. Dental Materials, 37, 1463-1485.
[Google Scholar] [CrossRef] [PubMed]
[25] Rosa, W.L.d.O.d., Piva, E. and Silva, A.F.d. (2015) Bond Strength of Universal Adhesives: A Systematic Review and Meta-Analysis. Journal of Dentistry, 43, 765-776.
[Google Scholar] [CrossRef] [PubMed]
[26] Pashley, D.H. and Tay, F.R. (2001) Aggressiveness of Contemporary Self-Etching Adhesives. Dental Materials, 17, 430-444.
[Google Scholar] [CrossRef
[27] Perdigão, J., Lopes, M.M. and Gomes, G. (2008) In Vitro Bonding Performance of Self-Etch Adhesives: II—Ultramorphological Evaluation. Operative Dentistry, 33, 534-549.
[Google Scholar] [CrossRef] [PubMed]
[28] Grégoire, G. and Ahmed, Y. (2007) Evaluation of the Enamel Etching Capacity of Six Contemporary Self-Etching Adhesives. Journal of Dentistry, 35, 388-397.
[Google Scholar] [CrossRef] [PubMed]
[29] dos Santos, K.T., Sundfeld, R.H., Garbin, C.A.S., Alexandre, R.S. de, Sundefeld, M.L.M.M. and Ceolim, B.N. (2008) Length of Resin Tags in Pit-and-Fissure Sealants: All-in-One Self-Etching Adhesive vs Phosphoric Acid Etching. Compendium of Continuing Education in Dentistry, 29, 186-192.
[30] Asselin, M.-E., Sitbon, Y., Fortin, D., Abelardo, L. and Rompre, P.H. (2009) Bond Strength of a Sealant to Permanent Enamel: Evaluation of 3 Application Protocols. Pediatric Dentistry, 31, 323-328.
[31] 刘茜, 周红艳, 曹灵, 等. 不同窝沟处理及酸蚀方式封闭剂界面的扫描电镜观察[J]. 口腔生物医学, 2011, 2(2): 85-88.
[32] Parco, T.M., Tantbirojn, D., Versluis, A. and Beiraghi, S. (2011) Microleakage of Self-Etching Sealant on Noncontaminated and Saliva-Contaminated Enamel. Pediatric Dentistry, 33, 479-483.
[33] 陈央兰, 武洁, 刘茜, 等. 一项新型窝沟封闭剂自酸蚀系统其物理性能的研究[J]. 临床口腔医学杂志, 2020, 36(3): 139-142.
[34] Erickson, R.L., Barkmeier, W.W. and Kimmes, N.S. (2009) Fatigue of Enamel Bonds with Self-Etch Adhesives. Dental Materials, 25, 716-720.
[Google Scholar] [CrossRef] [PubMed]
[35] Kensche, A., Dähne, F., Wagenschwanz, C., Richter, G., Viergutz, G. and Hannig, C. (2016) Shear Bond Strength of Different Types of Adhesive Systems to Dentin and Enamel of Deciduous Teeth in Vitro. Clinical Oral Investigations, 20, 831-840.
[Google Scholar] [CrossRef] [PubMed]
[36] Pitchika, V., Birlbauer, S., Chiang, M.-L., Schuldt, C., Crispin, A., Hickel, R. and Kühnisch, J. (2018) Shear Bond Strength and Microleakage of a New Self-Etch Adhesive Pit and Fissure Sealant. Dental Materials Journal, 37, 266-271.
[Google Scholar] [CrossRef] [PubMed]
[37] Schuldt, C., Birlbauer, S., Pitchika, V., Crispin, A., Hickel, R., Ilie, N. and Kühnisch, J. (2015) Shear Bond Strength and Microleakage of a New Self-Etching/Self-Adhesive Pit and Fissure Sealant. The Journal of Adhesive Dentistry, 17, 491-497.
[Google Scholar] [CrossRef] [PubMed]
[38] Peutzfeldt, A. and Nielsen, L.A. (2004) Bond Strength of a Sealant to Primary and Permanent Enamel: Phosphoric Acid versus Self-Etching Adhesive. Pediatric Dentistry, 26, 240-244.
[39] Al-Sarheed, M. (2006) Bond Strength of 4 Sealants Using Conventional Etch and a Self-Etching Primer. Journal of Dentistry for Children (Chicago, Ill.), 73, 37-41.
[40] Perdigão, J., Fundingsland, J.W., Duarte, S. and Lopes, M. (2005) Microtensile Adhesion of Sealants to Intact Enamel. International Journal of Paediatric Dentistry, 15, 342-348.
[Google Scholar] [CrossRef
[41] Bagherian, A. and Shirazi, A.S. (2018) Flowable Composite as Fissure Sealing Material? A Systematic Review and Meta-Analysis. British Dental Journal, 224, 92-97.
[Google Scholar] [CrossRef] [PubMed]
[42] Ramesh, H., Ashok, R., Rajan, M., Balaji, L. and Ganesh, A. (2020) Retention of Pit and Fissure Sealants versus Flowable Composites in Permanent Teeth: A Systematic Review. Heliyon, 6, e04964.
[Google Scholar] [CrossRef] [PubMed]
[43] Sharma, R., Prajapati, D., Nayak, U.A., Pawar, A. and Kappadi, D. (2018) Comparative Clinical Evaluation of Resin-Based Pit and Fissure Sealant and Self-Adhering Flowable Composite: An in Vivo Study. International Journal of Clinical Pediatric Dentistry, 11, 430-434.
[Google Scholar] [CrossRef] [PubMed]
[44] Gorseta, K., Borzabadi-Farahani, A., Vrazic, T. and Glavina, D. (2019) An In-Vitro Analysis of Microleakage of Self-Adhesive Fissure Sealant vs. Conventional and GIC Fissure Sealants. Dentistry Journal, 7, 32.
[Google Scholar] [CrossRef] [PubMed]
[45] Kim, H.-J., Choi, H.-J., Kim, K.-Y. and Kim, K.-M. (2020) Effect of Heat and Sonic Vibration on Penetration of a Flowable Resin Composite Used as a Pit and Fissure Sealant. Journal of Clinical Pediatric Dentistry, 44, 41-46.
[Google Scholar] [CrossRef] [PubMed]
[46] 周红艳, 张晓旻, 曹灵, 等. 不同渗透时间对窝沟封闭边缘封闭性能的影响[J]. 口腔医学, 2021, 41(7): 599-602.
[47] Sakkas, C., Khomenko, L. and Trachuk, I. (2013) A Comparative Study of Clinical Effectiveness of Fissure Sealing with and without Bonding Systems: 3-Year Results. European Archives of Paediatric Dentistry, 14, 73-81.
[Google Scholar] [CrossRef] [PubMed]
[48] Aman, N., Khan, F.R., Salim, A. and Farid, H. (2015) A Randomized Control Clinical Trial of Fissure Sealant Retention: Self Etch Adhesive versus Total Etch Adhesive. Journal of Conservative Dentistry, 18, 20-24.
[Google Scholar] [CrossRef] [PubMed]
[49] Bagherian, A., Sarraf Shirazi, A. and Sadeghi, R. (2016) Adhesive Systems under Fissure Sealants: Yes or No? A Systematic Review and Meta-Analysis. Journal of the American Dental Association (1939), 147, 446-456.
[Google Scholar] [CrossRef] [PubMed]
[50] Martignon, S. and Zarta, O.L. (2017) The Use of Adhesive Systems under Fissure Sealants Improves Their Retention, with Etch-and-Rinse Performing Better than Self-Etching Adhesive Systems. The Journal of Evidence-Based Dental Practice, 17, 56-58.
[Google Scholar] [CrossRef] [PubMed]
[51] Erbas Unverdi, G., Atac, S.A. and Cehreli, Z.C. (2017) Effectiveness of Pit and Fissure Sealants Bonded with Different Adhesive Systems: A Prospective Randomized Controlled Trial. Clinical Oral Investigations, 21, 2235-2243.
[Google Scholar] [CrossRef] [PubMed]
[52] Karaman, E., Yazici, A.R., Tuncer, D., Firat, E., Unluer, S. and Baseren, M. (2013) A 48-Month Clinical Evaluation of Fissure Sealants Placed with Different Adhesive Systems. Operative Dentistry, 38, 369-375.
[Google Scholar] [CrossRef
[53] Botton, G., Morgental, C.S., Scherer, M.M., Lenzi, T.L., Montagner, A.F. and Rocha, R.d.O. (2016) Are Self-Etch Adhesive Systems Effective in the Retention of Occlusal Sealants? A Systematic Review and Meta-Analysis. International Journal of Paediatric Dentistry, 26, 402-411.
[Google Scholar] [CrossRef] [PubMed]
[54] Feigal, R.J. and Quelhas, I. (2003) Clinical Trial of a Self-Etching Adhesive for Sealant Application: Success at 24 Months with Prompt L-Pop. American Journal of Dentistry, 16, 249-251.
[55] 计艳, 林梓桐, 郑丽纯, 等. 自酸蚀粘结剂在磨牙窝沟封闭中的临床应用效果分析[J]. 临床口腔医学杂志, 2016, 32(11): 665-667.
[56] Kühnisch, J., Mansmann, U., Heinrich-Weltzien, R. and Hickel, R. (2012) Longevity of Materials for Pit and Fissure Sealing—Results from a Meta-Analysis. Dental Materials, 28, 298-303.
[Google Scholar] [CrossRef] [PubMed]
[57] Mickenautsch, S. and Yengopal, V. (2013b) Validity of Sealant Retention as Surrogate for Caries Prevention—A Systematic Review. PLoS ONE, 8, e77103.
[Google Scholar] [CrossRef] [PubMed]
[58] Yazici, A.R., Bayazit, E.O., Kutuk, Z.B., Ozgunaltay, G., Ergin, E. and Berber, A. (2018) Clinical Follow-Up of a Fissure Sealant Placed Using Different Adhesive Protocols: A 24-Month Split-Mouth Study. Operative Dentistry, 43, 362-371.
[Google Scholar] [CrossRef
[59] 张笋, 秦满, 李静. 自酸蚀和磷酸酸蚀窝沟封闭术的临床比较[J]. 华西口腔医学杂志, 2008, 26(6): 630-632.
[60] Venker, D.J., Kuthy, R.A., Qian, F. and Kanellis, M.J. (2004) Twelve-Month Sealant Retention in a School-Based Program Using a Self-Etching Primer/Adhesive. Journal of Public Health Dentistry, 64, 191-197.
[Google Scholar] [CrossRef] [PubMed]
[61] 黄诺蓓, 刘丽君, 陈志斌, 等. 窝沟封闭术酸蚀方法研究[J]. 中国实用口腔科杂志, 2013, 6(10): 621-623.
[62] Fuks, A.B. and Kupietzky, A. (2007) Assessment of Two Curing Systems in a Self-Etching Primer/Adhesive Sealant: A Preliminary Study for a Clinical Trial. European Archives of Paediatric Dentistry, 8, 171-174.
[Google Scholar] [CrossRef
[63] 刘晶. 观察使用自酸蚀粘结剂对第一恒磨牙窝沟封闭的临床作用[J]. 全科口腔医学电子杂志, 2018, 5(27): 24-25.
[64] 王伟德. 自酸蚀粘接剂用于成人窝沟封闭防龋效果研究[J]. 延安大学学报(医学科学版), 2018, 16(1): 45-47.
[65] 苏红如, 徐培成, 钱文昊. 应用一步法自酸蚀黏结系统进行窝沟封闭的效果评价[J]. 上海口腔医学, 2016, 25(3): 317-321.
[66] 王璐, 高云, 韩耀伦. 自酸蚀与磷酸酸蚀对第一恒磨牙窝沟封闭术的临床比较[J]. 中国继续医学教育, 2016, 8(11): 151-153.
[67] 彭思敏, 赵玮, 林家成, 等. 自酸蚀黏结剂对恒牙窝沟封闭的疗效评价[J]. 上海口腔医学, 2006(6): 571-574.
[68] Mickenautsch, S. and Yengopal, V. (2013a) Retention Loss of Resin Based Fissure Sealants—A Valid Predictor for Clinical Outcome? The Open Dentistry Journal, 7, 102-108.
[Google Scholar] [CrossRef] [PubMed]
[69] 高雪彬, 张琦, 李晶, 等. 低龄儿童行窝沟封闭术时酸蚀剂选择的临床研究[J]. 国际口腔医学杂志, 2017, 44(4): 433-436.
[70] 王丽娜. 自酸蚀法与磷酸酸蚀法应用于低龄儿童乳磨牙窝沟封闭术的临床效果比较研究[J]. 中国实用口腔科杂志, 2018, 11(10): 621-623.
[71] Cocco, A.R., Cuevas-Suárez, C.E., Liu, Y., Lund, R.G., Piva, E. and Hwang, G. (2020) Anti-Biofilm Activity of a Novel Pit and Fissure Self-Adhesive Sealant Modified with Metallic Monomers. Biofouling, 36, 245-255.
[Google Scholar] [CrossRef] [PubMed]