淋巴细胞减少预测创伤性脊髓损伤患者结局
Lymphocytopenia Predicts Outcomes in Patients with Traumatic Spinal Cord Injury
DOI: 10.12677/ACM.2021.1111794, PDF,   
作者: 张崇辉#, 丁长赓, 郑 杰, 车沅沅, 曹鑫意, 程 明, 王玉海*：安徽医科大学无锡临床学院，江苏 无锡；联勤保障部队第九〇四医院神经外科，江苏 无锡
关键词: 创伤性脊髓损伤；淋巴细胞减少症；预后；呼吸道感染；Traumatic Spinal Cord Injury； Lymphocytopenia； Prognosis； Respiratory Tract Infection
摘要: 目的：探讨淋巴细胞减少(Lymphocytopenia，LOA)与创伤性脊髓损伤(SCI)患者呼吸道感染(RTI)及临床预后的关系。方法：选取本院收治的161例创伤性脊髓损伤患者，根据入院淋巴细胞计数将患者分为淋巴细胞减少组(LOA) (n = 76)和无淋巴细胞减少组(NoLOA) (n = 85)。根据入院与出院时美国脊髓损伤协会损伤量表(AIS)等级是否改善将患者预后分为预后良好及预后不良。结合患者病历和辅助检查相结合以判断呼吸道感染情况。采用Person X2检验分析淋巴细胞减少和呼吸道感染及临床预后的关系。结果：LOA组与预后良好相关(P < 0.05)，而两组间呼吸道感染率差异无统计学意义(P > 0.05)。结论：淋巴细胞减少症与预后良好相关，但不能认为与呼吸道感染发生率有关。
Abstract: Objective: To investigate the relationship between lymphocytopenia (LOA) and respiratory tract infection (RTI) and clinical prognosis in patients with traumatic spinal cord injury (SCI). Methods: A total of 161 patients with traumatic spinal cord injury admitted to our hospital were divided into lymphocytopenia group (LOA) (n = 76) and No LOA group (n = 85) according to the lymphocytopenia count. Outcomes were classified as good or poor based on improvement in the American Spinal Injury Association Impairment Scale (AIS) rating at admission and discharge. The patient’s medical record and auxiliary examination were combined to determine respiratory tract infection. The relationship between lymphocytopenia and respiratory tract infection and clinical prognosis was analyzed by Person X2 test. Results: LOA group was correlated with good prognosis (P < 0.05), but there was no significant difference in respiratory tract infection incidence between the two groups (P > 0.05). Conclusions: Lymphocytopenia is associated with a good prognosis, but cannot be considered associated with the incidence of respiratory tract infection.
文章引用：张崇辉, 丁长赓, 郑杰, 车沅沅, 曹鑫意, 程明, 王玉海. 淋巴细胞减少预测创伤性脊髓损伤患者结局[J]. 临床医学进展, 2021, 11(11): 5373-5378. https://doi.org/10.12677/ACM.2021.1111794

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