十二指肠乳头肿瘤的治疗进展
Advances in the Treatment of Duodenal Papillary Carcinomas
摘要: 十二指肠乳头肿瘤主要包括腺瘤和腺癌，多为偶然发现或累及胆胰管并发黄疸或急性胰腺炎时被发现，病灶可浸润周围组织，并通过血液或淋巴途径转移。十二指肠乳头肿瘤的治疗主要以外科手术为主，随着消化道内镜的发展，部分病变可经内镜下治疗，本文将对十二指肠肿瘤的治疗方式及适应症的进展进行总结分析。
Abstract: Duodenal neoplasms include adenomas and adenocarcinomas, which are found incidentally or due to obstructive jaundice or acute pancreatitis. The lesions can invade the surrounding tissues and even metastasize through the blood or lymphatic route. Pancreaticoduodenectomy is considered the primary treatment for ampullary neoplasms. However, with the advanced endoscopic techniques development, more and more duodenal lesions can be cured by using duodenoscopic treatment. But, there is uniformed consensus on the appropriate treatment. The following article will summarize the progress of treatment methods and indicators of duodenal papilla carcinomas.
文章引用：毕盛华, 孙学国, 荆雪. 十二指肠乳头肿瘤的治疗进展[J]. 临床医学进展, 2021, 11(11): 5420-5424. https://doi.org/10.12677/ACM.2021.1111801

参考文献

[1] Pavlovic-Markovic, A., Dragasevic, S., Krstic, M., et al. (2019) Assessment of Duodenal Adenomas and Strategies for Curative Therapy. Digestive Diseases, 37, 374-380. [Google Scholar] [CrossRef] [PubMed]
[2] Valli, P.V., Mertens, J.C., Sonnenberg, A., et al. (2017) Nonampullary Duodenal Adenomas Rarely Recur after Complete Endoscopic Resection: A Swiss Experience Including a Literature Review. Digestion, 96, 149-157. [Google Scholar] [CrossRef] [PubMed]
[3] Fritzsche, J.A., Klein, A., Beekman, M.J., et al. (2020) Endoscopic Papillectomy; a Retrospective International Multicenter Cohort Study with Long-Term Follow-Up. Surgical Endoscopy. [Google Scholar] [CrossRef] [PubMed]
[4] Ahn, D.W., Ryu, J.K., Kim, J., et al. (2013) Endoscopic Papillectomy for Benign Ampullary Neoplasms: How Can Treatment Outcome Be Predicted? Gut and Liver, 7, 239-245. [Google Scholar] [CrossRef] [PubMed]
[5] Sahar, N., Krishnamoorthi, R., Kozarek, R.A., et al. (2020) Long-Term Outcomes of Endoscopic Papillectomy for Ampullary Adenomas. Digestive Diseases and Sciences, 65, 260-268. [Google Scholar] [CrossRef] [PubMed]
[6] Kang, S.H., Kim, K.H., Kim, T.N., et al. (2017) Therapeutic Outcomes of Endoscopic Papillectomy for Ampullary Neoplasms: Retrospective Analysis of a Multicenter Study. BMC Gastroenterology, 17, 69. [Google Scholar] [CrossRef] [PubMed]
[7] 王伟, 郝璐, 施新岗, 李兆申. 经内镜十二指肠乳头病变切除术的治疗价值研究[J]. 中华消化内镜杂志, 2017, 34(7): 480-484. [Google Scholar] [CrossRef] 
[8] Gaspar, J.P., Stelow, E.B. and Wang, A.Y. (2016) Approach to the Endoscopic Resection of Duodenal Lesions. World Journal of Gastroenterology, 22, 600-617. [Google Scholar] [CrossRef] [PubMed]
[9] 隗永秋, 邹巧直, 张澍田, 等. 内镜在原发性十二指肠占位性病变中的应用价值[J]. 中华消化内镜杂志, 2019, 36(5): 323-327. [Google Scholar] [CrossRef] 
[10] 吴小超, 吴沛瑶, 缪林, 等. 内镜下治疗十二指肠占位性病变的安全性、有效性及临床价值研究[J]. 中国内镜杂志, 2018, 24(1): 5-10. [Google Scholar] [CrossRef] 
[11] 刘方, 王子恺, 郭旭, 等. 十二指肠乳头肿瘤[J]. 中华消化杂志, 2020, 40(1): 56-60. [Google Scholar] [CrossRef] 
[12] 李琛, 谭玉勇, 刘德良, 等. 内镜黏膜下剥离术治疗十二指肠病变的临床疗效分析[J]. 中华消化内镜杂志, 2020, 37(3): 190-194. [Google Scholar] [CrossRef] 
[13] Hüttner, F.J., Fitzmaurice, C., Schwarzer, G., et al. (2016) Pylorus-Preserving Pancreaticoduodenectomy (pp Whipple) versus Pancreaticoduodenectomy (Classic Whipple) for Surgical Treatment of Periampullary and Pancreatic Carcinoma. Cochrane Database of Systematic Reviews, 2, Cd006053. [Google Scholar] [CrossRef] 
[14] Chini, P. and Draganov, P.V. (2011) Diagnosis and Management of Ampullary Adenoma: The Expanding Role of Endoscopy. World Journal of Gastrointestinal Endoscopy, 3, 241-247. [Google Scholar] [CrossRef] [PubMed]
[15] 黄留业, 崔俊, 郭娟, 吴承荣. 内镜切除术治疗十二指肠乳头部肿瘤的临床分析[J]. 中华消化内镜杂志, 2016, 33(11): 798-800. [Google Scholar] [CrossRef] 
[16] Ochiai, Y., Kato, M., Kiguchi, Y., et al. (2019) Current Status and Challenges of Endoscopic Treatments for Duodenal Tumors. Digestion, 99, 21-26. [Google Scholar] [CrossRef] [PubMed]
[17] 沈永华, 曹俊, 邹晓平, 王雷. 胆管支架置入在内镜下十二指肠乳头腺瘤切除术中的应用[J]. 国际消化病杂志, 2016, 36(6): 375-377. [Google Scholar] [CrossRef] 
[18] Song, T.J., Park, D.H., Seo, D.W., et al. (2021) Long-Term Outcomes of Endoscopic Papillectomy for Early-Stage Cancer in Duodenal Ampullary Adenoma: Comparison to Surgical Treatment. Journal of Gastroenterology and Hepatology, 36, 2315-2323. [Google Scholar] [CrossRef] [PubMed]
[19] 季超超, 冯德元, 等. 原发性十二指肠肿瘤手术疗效分析[J]. 中华临床医师杂志, 2013, 7(9): 3793-3797. [Google Scholar] [CrossRef] 
[20] 夏华, 孙维佳. 十二指肠乳头癌临床分析: 附80例报告[J]. 中国普通外科杂志, 2018,2 7(4): 468-473. [Google Scholar] [CrossRef] 
[21] 邹勇, 欧阳霆, 王波, 等. 浅谈局部切除治疗十二指肠乳头肿瘤的临床观察[J]. 中国实用医药, 2013, 8(6): 53. [Google Scholar] [CrossRef] 
[22] 任雪峰, 黄强, 谢放, 王世杰. 十二指肠乳头部肿瘤的诊断及治疗: 附64例报告[J]. 中国普通外科杂志, 2009, 18(1): 75-78. [Google Scholar] [CrossRef] 
[23] 叶振伟, 王在国. 十二指肠乳头癌的诊断及胰十二指肠切除经验[J]. 中华肝胆外科杂志, 2018, 24(7): 467-469. [Google Scholar] [CrossRef] 
[24] 付学良, 杨建宇, 孙勇伟, 等. 十二指肠乳头癌行胰十二指肠切除术患者预后相关因素分析[J]. 中华普通外科杂志, 2019, 34(12): 1021-1025. [Google Scholar] [CrossRef] 
[25] 杨维良, 聂刚, 赵刚. 十二指肠乳头肿瘤的诊断与治疗[J]. 中国普通外科杂志, 2007, 10(4): 347-349. [Google Scholar] [CrossRef] 
[26] 程芮, 张澍田. 十二指肠乳头肿瘤内镜诊治现状[J]. 中国医刊, 2016, 51(1): 3-6. [Google Scholar] [CrossRef] 
[27] 杨雨, 吴宝强, 蔡辉华, 孙冬林. 保留幽门的胰十二指肠切除术与传统胰十二指肠切除术治疗胰腺疾病及壶腹周围癌的术后恢复情况对比分析[J]. 南京医科大学学报, 2018, 38(10): 1435-1438. [Google Scholar] [CrossRef] 
[28] Calderon, E., Day, R.W., Stucky, C.C., et al. (2020) Comparative Effectiveness of Pylorus-Preserving versus Standard Pancreaticoduodenectomy in Clinical Practice. Pancreas, 49, 568-573. [Google Scholar] [CrossRef] 

为你推荐