以全身多发淋巴结肿大为首发表现的T-大颗粒淋巴细胞白血病1例报道并文献复习

T-Large Granular Lymphocytic Leukemia with Systemic Multiple Lymphadenopathy as the First Manifestation: A Case Report and Literature Review

摘要: T-大颗粒淋巴细胞白血病(T-LGLL)是一种罕见的淋巴细胞增殖性疾病，其主要的临床表现为血细胞减少、脾大、自身免疫性疾病，B症状罕见，淋巴结肿大非常罕见。回顾性分析1例以全身多发淋巴结肿大为首发表现的T-LGLL患者的临床资料，并查阅、复习相关文献，以提高临床医师对T-LGLL的认识。

Abstract: T-Large granular lymphocytic leukemia (T-LGLL) is a rare lymphoproliferative disorder disease. The main clinical manifestations are cytopenia, splenomegaly and autoimmune disease, B-symptoms are rare, whilst lymphadenopathy is very rare. The clinical data of a case diagnosed as T-LGLL which multiple systemic lymphadenopathy was the first manifestation was analyzed retrospectively and the related literatures were reviewed to improve clinicians’ awareness of the T-LGLL.