危重症患儿营养与骨密度研究进展

Research Progress on Nutrition and Bone Density in Critically Ill Children

摘要: 随着重症医学技术的高速发展，越来越多的危重症患儿得以存活。但该类患儿普遍存在中高度营养不良风险，生存后的营养评估与管理一直是研究热点。同时，机体应激反应及能量过度消耗还会引起骨代谢改变，从而影响骨骼的吸收与重建，导致其发生骨质疏松甚至骨折的风险大大增加。这不仅为患儿疾病诊疗带来困难，也不利于后期康复训练的进行。目前关于儿童营养与骨密度相关研究甚多，却鲜有研究探讨危重症患儿营养与骨密度的关系。为此，本文将从危重症患儿营养对骨密度影响的角度切入展开分析和讨论，以期为临床医生从营养方面防治危重症患儿骨质疏松提供借鉴和参考。

Abstract: With the rapid development of critical care medicine technology, more and more critically ill children have survived. But this type of children is generally at risk of moderate to high malnutrition, nutritional assessment and management after survival has always been a research focus. At the same time, the body’s stress response and excessive energy consumption can also cause changes in bone metabolism, which will affect the absorption and reconstruction of bone, leading to a greatly increased risk of osteoporosis and even fractures. This not only brings difficulties to the diagnosis and treatment of children’s diseases, but also is not conducive to the subsequent rehabilitation training. At present, there are many studies on the relationship between nutrition and bone density in children, but few studies have explored the relationship between nutrition and bone density in critically ill children. Thus, this article will analyze and discuss the impact of nutrition in critically ill children on bone density in order to provide reference for clinicians to prevent and treat osteoporosis in critically ill children in terms of nutrition.