妊娠合并马凡综合征1例并文献复习

Pregnancy Complicated with Marfan Syndrome: A Case Report and Literature Review

摘要: 马凡综合征又称为马方综合征，为一种遗传性结缔组织疾病，为常染色体显性遗传，患病特征为四肢、手指、脚趾细长不匀称，身高明显超出常人，伴有心血管系统异常。妊娠合并马凡综合征较为罕见，易误诊、漏诊，且妊娠风险极大。近期青大附院收治1例妊娠合并马凡综合征患者，合并腹主动脉瘤形成，发病较为隐匿，且累及双侧髂血管，病情较为凶险，报道如下。

Abstract: Marfan syndrome, is a hereditary connective tissue disease, which is autosomal dominant. The disease is characterized by long and uneven limbs, fingers and toes, significantly higher than normal height, and cardiovascular system abnormalities. Pregnancy with marfan syndrome is rare, easy to be misdiagnosed, missed diagnosis, and pregnancy risk is great. Recently, a pregnant patient with marfan syndrome was admitted to the affiliated hospital of Qingdao University, with the formation of abdominal aortic aneurysm, the disease was more insidious, and involved bilateral iliac vessels, and the disease was more dangerous, as reported below.