高泌乳素血症性不孕症的临床研究进展

Clinical Research Progress of Hyperprolactinemic Infertility

摘要: 不孕症(infertility)是最常见的妇科疾病之一。我国育龄夫妇中，8.5%~20%的妇女患有不孕症，该症对患者及其家庭造成了极大的不良影响。女性不孕症患者中，高泌乳素血症(hyperprolactinemia, HPRL)的患病率高达15%~20%，HPRL被认为是引起育龄妇女不孕的重要原因。而目前临床上关于高泌乳素血症性不孕症的发病机制及诊疗方案还有待深入研究，探寻更多的证据。有望使提升高泌乳素血症性不孕症的诊疗水平和改善患者心理健康及生活质量成为可能。本文将从HPRL性不孕症的病因、发病机制、诊断和治疗等方面进行综述，阐明该病的研究现状及对未来提出展望。

Abstract: Infertility is one of the most common gynecological diseases. Among couples of childbearing age in China, 8.5%~20% of women suffer from infertility, which has caused great adverse effects on patients and their families. Among female infertility patients, the prevalence of hyperprolactinemia (HPRL) is as high as 15%~20%, and HPRL is considered to be an important cause of infertility in women of childbearing age. At present, the pathogenesis, diagnosis and treatment of HPRL infertility need to be further studied to explore more evidence. It is expected to improve the diagnosis and treatment level of HPRL infertility and improve the mental health and quality of life of patients. In this paper, the etiology, pathogenesis, diagnosis and treatment of HPRL infertility were reviewed, and the research status of this disease was clarified and the prospects for the future were put forward.