血管内治疗动脉粥样硬化性前循环大血管闭塞所致急性缺血性卒中的治疗进展
Progress in Endovascular Treatment of Acute Ischemic Stroke Due to Atherosclerotic Anterior Circulation Large Vessel Occlusion
DOI: 10.12677/ACM.2022.121028, PDF,   
作者: 胡 元：延安大学附属医院，陕西 延安；李 健：延安大学附属医院神经外科，陕西 延安
关键词: 颅内动脉粥样硬化；急性缺血性卒中；大血管闭塞；血管内治疗；Intracranial Atherosclerosis； Acute Ischemic Stroke； Occlusion of Large Vessels； Endovascular Therapy
摘要: 脑卒中是常见疾病之一，其具有高致死率、高致残率、高复发率，严重威胁我国人民生命和健康，同时给家庭和社会带来沉重的经济负担。缺血性脑血管病(Ischemic cerebrovascular disease, ICD)是最常见的脑卒中类型，占全部脑卒中的60%~80%。发病早期4.5 h内，静脉注射t-PA成为急性缺血性卒中的标准治疗方案。然而2015年五项具有里程碑意义多中心随机临床试验证实血管内治疗AIS优于静脉溶栓，因此，对大血管闭塞所致的AIS，血管内治疗开始成为标准治疗方案。相较于心源性栓塞型，血管内治疗动脉粥样硬化引起的大血管闭塞，手术时间更长，手术复杂性更高。本文就血管内治疗动脉粥样硬化相关的前循环大血管闭塞所致急性缺血性卒中的治疗进展进行综述。
Abstract: Cerebral apoplexy is one of the common diseases, which has high mortality, high disability rate and high recurrence rate, seriously threatening the life and health of Chinese people, and at the same time bringing heavy economic burden to family and society. Ischemic cerebrovascular disease (ICD) is the most common type of stroke, accounting for 60% to 80% of all strokes. Intravenous t-PA within 4.5 h of early onset became the standard treatment for acute ischemic stroke. However, five landmark multicenter randomized clinical trials in 2015 confirmed that endovascular treatment for AIS is superior to intravenous thrombolysis. Therefore, endovascular treatment has become the standard treatment for AIS caused by large vessel occlusion. Endovascular treatment for large vessel occlusion caused by atherosclerosis is longer and more complicated than cardiogenic embolism. This article reviews the progress of endovascular treatment for acute ischemic stroke caused by anterior circulation large vessel occlusion associated with atherosclerosis.
文章引用：胡元, 李健. 血管内治疗动脉粥样硬化性前循环大血管闭塞所致急性缺血性卒中的治疗进展[J]. 临床医学进展, 2022, 12(1): 177-182. https://doi.org/10.12677/ACM.2022.121028

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