功能磁共振在面肌痉挛中的研究进展
Research Progress in Functional Magnetic Resonance Imaging of Brain in Hemifacial Spasm
DOI: 10.12677/ACM.2022.122156, PDF,   
作者: 张天然：济宁医学院临床医学院，山东 济宁；齐先龙*：山东省济宁市第一人民医院放射科，山东 济宁
关键词: 面肌痉挛；脑功能；磁共振成像；Hemifacial Spasm； Brain Function； Magnetic Resonance Imaging
摘要: 面肌痉挛(HFS)是一种慢性运动障碍疾病，严重影响患者的生活质量及社会交往。以前普遍认为面肌痉挛是由于血管压迫神经造成的，但随着神经影像学的发展，越来越多的证据表明，面肌痉挛患者的中枢系统存在结构及功能的异常。本文从面肌痉挛患者脑灰质结构、脑白质结构和脑功能三个方面的变化，对面肌痉挛的功能磁共振研究进展情况进行综述。
Abstract: Hemifacial spasm (HFS) is a chronic movement disorder, which frequently causes social embarrassment, has mental distress and impacts patient’s quality of life. Neurovascular compression of the root exit zone (REZ) of the facial nerve is proven to be the most common cause of HFS. With the development of neuroimage, it has been proved that there are structural and functional abnormalities in the central system of patients with hemifacial spasm. This paper systematically reviewed the latest achievements in brain imaging research of hemifacial spasm in three aspects, including structural alterations of gray matter, structural alterations of white matter and functional abnormalities.
文章引用：张天然, 齐先龙. 功能磁共振在面肌痉挛中的研究进展[J]. 临床医学进展, 2022, 12(2): 1062-1066. https://doi.org/10.12677/ACM.2022.122156

参考文献

[1] 上海交通大学颅神经疾病诊治中心. 面肌痉挛诊疗中国专家共识[J]. 中国微侵袭神经外科杂志, 2014, 19(11): 528-532. [Google Scholar] [CrossRef] 
[2] 王天宇, 高俊, 王鑫, 等. 显微血管减压术对偏侧面肌痉挛患者生活质量的影响[J]. 基础医学与临床, 2018, 38(7): 1003-1006. [Google Scholar] [CrossRef] 
[3] 程亚鹏, 李涛. 面肌痉挛病因学发病机制的研究进展[J]. 中西医结合心脑血管病杂志, 2017, 15(17): 2128-2131. [Google Scholar] [CrossRef] 
[4] Zheng, X.S., Hong, W.Y., Tang, Y.D., et al. (2012) Sympathetic Nerves Bridge the Cross-Transmission in Hemifacial Spasm. Neuroscience Letters, 517, 52-55. [Google Scholar] [CrossRef] [PubMed]
[5] Shimizu, M., Suzuki, Y., Kiyosawa, M., et al. (2012) Glucose Hypermetabolism in the Thalamus of Patients with Hemifacial Spasm. Movement Disorders, 27, 519-525. [Google Scholar] [CrossRef] [PubMed]
[6] 包书圣, 赵璨, 包星星, 饶家声. 基于体素的形态学分析在脊髓损伤中的研究进展[J]. 中国医学物理学杂志, 2021, 38(9): 1072-1076.
[7] Bao, F., Wang, Y., Liu, J., et al. (2015) Structural Changes in the CNS of Patients with Hemifacial Spasm. Neuroscience, 289, 56-62. [Google Scholar] [CrossRef] [PubMed]
[8] Xu, H., Guo, C.G., Li, H.N., et al. (2019) Structural and Functional Amygdala Abnormalities in Hemifacial Spasm. Frontiers in Neurology, 10, Article No. 393. [Google Scholar] [CrossRef] [PubMed]
[9] Tu, Y., Yu, T., Wei, Y.X., et al. (2016) Structural Brain Alterations in Hemifacial Spasm: A Voxel-Based Morphometry and Diffusion Tensor Imaging Study. Clinical Neurophysiology, 127, 1470-1474. [Google Scholar] [CrossRef] [PubMed]
[10] 陆海锋, 张绮婷, 张记磊, 等. 面肌痉挛的静息态脑功能和结构的初步探究[J]. 磁共振成像, 2018, 9(1): 38-42. [Google Scholar] [CrossRef] 
[11] Xie, Y., Zhang, Y., Qin, W., et al. (2017) White Matter Microstructural Abnormalities in Type 2 Diabetes Mellitus: A Diffusional Kurtosis Imaging Analysis. American Journal of Neuroradiology, 38, 617-625. [Google Scholar] [CrossRef] 
[12] Jeong, H., Kim, J., Choi, H.S., et al. (2011) Changes in Integrity of Normal-Appearing White Matter in Patients with Moyamoya Disease: A Diffusion Tensor Imaging Study. American Journal of Neuroradiology, 32, 1893-1898. [Google Scholar] [CrossRef] 
[13] Li, R., Chang, N., Liu, Y., et al. (2020) The Integrity of the Substructure of the Corpus Callosum in Patients with Right Classic Trigeminal Neuralgia—A Diffusion Tensor Imaging Study. Journal of Craniofacial Surgery, 32, 632-636. [Google Scholar] [CrossRef] 
[14] Acosta-Cabronero, J., Williams, G.B., Pengas, G., et al. (2010) Absolute Diffusivities Define the Landscape of White Matter Degeneration in Alzheimer’s Disease. Brain, 133, 529-539. [Google Scholar] [CrossRef] [PubMed]
[15] Zhang, Y.Y., Mao, Z.Q., Cui, Z.Q., et al. (2018) Diffusion Tensor Imaging of Axonal and Myelin Changes in Classical Trigeminal Neuralgia. World Neurosurgery, 112, e597-e607. [Google Scholar] [CrossRef] [PubMed]
[16] Rizk, M.M., Rubin-Falcone, H., Keilp, J., et al. (2017) White Matter Correlates of Impaired Attention Control in Major Depressive Disorder and Healthy Volunteers. Journal of Affective Disorders, 222, 103-111. [Google Scholar] [CrossRef] [PubMed]
[17] 郭鹏德, 赵朋波, 赵晶, 等. MR扩散张量成像评估非动脉炎性前部缺血性视神经病变进展程度的价值[J]. 中华放射学杂志, 2018, 52(10): 761-765. [Google Scholar] [CrossRef] 
[18] Squarcina, L., Houenou, J., Altamura, A.C., et al. (2017) Association of Increased Genotypes Risk for Bipolar Disorder with Brain White Matter Integrity Investigated with Tract-Based Spatial Statistics. Journal of Affective Disorders, 221, 312-317. [Google Scholar] [CrossRef] [PubMed]
[19] Guo, C.G., Xu, H., Niu, X., et al. (2020) Abnormal Brain White Matter in Patients with Hemifacial Spasm: A Diffusion Tensor Imaging Study. Neuroradiology, 62, 369-375. [Google Scholar] [CrossRef] [PubMed]
[20] 张天然, 齐先龙, 李蕊, 等. 基于DTI探讨面肌痉挛患者胼胝体亚结构区域完整性的损伤[J]. 医学影像学杂志, 2021, 31(11): 1832-1835+1863.
[21] Zhang, J., Yu, Q.Y., Gu, P., et al. (2022) Brain Structure Alterations in Hemifacial Spasm: A Diffusion Tensor Imaging Study. Clinical EEG and Neuroscience, 53, 165-172. [Google Scholar] [CrossRef] [PubMed]
[22] 吴兰香, 吴伟. 静息态功能磁共振成像在局灶性肌张力障碍中的应用研究进展[J/OL]. 解放军医学杂志. http://kns.cnki.net/kcms/detail/11.1056.R.20211210.1046.002.html, 2022-01-19.
[23] 李晓露, 夏建国, 邹红梅, 等. non-NPSLE患者基于静息态fMRI的局部一致性研究[J]. 放射学实践, 2021, 36(12): 1467-1473. [Google Scholar] [CrossRef] 
[24] Tu, Y., Wei, Y.X., Sun, K., et al. (2015) Altered Spontaneous Brain Activity in Patients with Hemifacial Spasm: A Resting-State Functional MRI Study. PLoS ONE, 10, e0116849. [Google Scholar] [CrossRef] [PubMed]
[25] 卫永旭, 赵卫国, 涂业. 面肌痉挛发病机制的静息态功能磁共振研究[J]. 中华神经外科杂志, 2015, 31(5): 482-486. [Google Scholar] [CrossRef] 
[26] Niu, X., Xu, H., Guo, C.G., et al. (2020) Strengthened Thalamoparietal Functional Connectivity in Patients with Hemifacial Spasm: A Cross-Sectional Resting-State fMRI Study. The British Journal of Radiology, 93, Article ID: 20190887. [Google Scholar] [CrossRef] [PubMed]
[27] Gao, W.W., Yang, D., Zhang, Z., et al. (2021) Altered Cortical-Striatal Network in Patients With Hemifacial Spasm. Frontiers in Human Neuroscience, 15, Article ID: 770107. [Google Scholar] [CrossRef] [PubMed]

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