急性脑梗死患者24小时动态血压、动态心率与心功能的相关性研究

Correlation Study among 24-Hour Ambulatory Blood Pressure, Ambulatory Heart Rate and Cardiac Function in Patients with Acute Cerebral Infarction

摘要: 目的：探讨急性脑梗死(ACI)患者24小时动态血压、动态心率与心功能的相关性。方法：对156例ACI患者及112例体检者(对照)行24 h动态血压和24 h动态心率监测及心脏彩超检查，获取24小时血压、心率及心脏左室舒张末期内径、室间隔厚度、左室射血分数等参数，分析两组间差异。结果：1) ACI组收缩压和舒张压均高于对照组，差异有统计学意义(P < 0.05)。2) ACI组24 h心率、白昼心率及24 h心率标准差、白昼心率标准差均低于对照组，差异有统计学意义(P < 0.05)。3) ACI组左室舒张末期内径及室间隔厚度高于对照组，差异有统计学意义(P < 0.05)。ACI组左室射血分数低于对照组，差异有统计学意义(P < 0.05)。结论：ACI患者急性期血压升高及心率减低可能是机体代偿反应，提高心脏泵血功能可能有助于改善脑的血供。

Abstract: Objective: To investigate the correlation among 24-hour ambulatory blood pressure, 24-hour ambulatory heart rate and cardiac function in patients with acute cerebral infarction (ACI). Method: 156 patients with ACI and 112 physical examinees (controls) were monitored by 24 h ambulatory blood pressure, 24 h ambulatory heart rate and cardiac color Doppler ultrasound. The parameters such as 24 h blood pressure, heart rate, left ventricular end diastolic diameter, ventricular septal thickness and left ventricular ejection fraction were obtained, and the differences between the two groups were analyzed. Result: 1) The systolic and diastolic blood pressure in ACI group were significantly higher than those in control group (P < 0.05). 2) The 24-hour heart rate, daytime heart rate, 24-hour heart rate standard deviation and daytime heart rate standard deviation in ACI group were lower than those in the control group (P < 0.05). 3) The left ventricular end diastolic diameter and ventricular septal thickness in ACI group were significantly higher than those in control group (P < 0.05). The left ventricular ejection fraction in ACI group was significantly lower than that in control group (P < 0.05). Conclusion: The increase of blood pressure and decrease of heart rate in patients with ACI may be the compensatory response of the body. Improving the blood pumping function of the heart may help to improve the blood supply of the brain.