新生儿毛细血管渗漏综合征临床表现及影像学分析

Analysis of Clinical Characteristics and Imaging Features of Capillary Leak Syndrome in Neonates

摘要: 目的：分析新生儿毛细血管渗漏综合征的临床症状及影像学表现，为临床诊断和治疗提供依据。方法：回顾性分析2019年1月~2021年3月我院26例不同病因引起的新生儿毛细血管渗漏综合征确诊病例的临床表现及胸片、B超的影像学特征。结果：新生儿毛细血管渗漏综合征临床表现以全身症状为主。在渗漏前期即可在胸片上出现异常，可有纹理增多、透光度减低、磨玻璃影、片絮影等不同渗出表现，渗漏期渗出程度加重，恢复期渗出逐渐吸收。B超发现患儿常合并腹腔积液，部分患儿可出现胆囊壁增厚，而较少发现心包积液及胸腔积液。结论X线及超声检查特征对于新生儿毛细血管渗漏综合征的诊治及预后判断有重要意义，胸部X线改变的程度基本与临床病期一致，能及时反应病变的发展变化情况。

Abstract: Objective: To analyze the clinical symptoms and imaging manifestations of capillary leakage syndrome in neonates, and to provide evidence for clinical diagnosis and treatment. Methods: 26 cases of neonatal capillary leakage syndrome caused by different etiology in our hospital were retrospectively analyzed in terms of clinical manifestations and imaging characteristics about chest radiograph and ultrasound from January 2019 to March 2021. Results: The clinical symptoms of neonatal capillary leakage syndrome were mainly systemic. In the early stage of leakage, chest radiographsmay be abnormal, such as increased texture, reduced light transmitance, ground glass shadow, film and other exudation performance. The degree of exudation is aggravated in the leakage stage and the exudation is gradually absorbed in the recovery stage. Ultrasound found these children were often complicated with peritoneal effusion, and some children may have thickened gallbladder wall, while pericardial effusion and pleural effusion were rare. Conclusions: The characteristics of X-ray and ultrasound examination are of great significance for the diagnosis, treatment and prognosis of capillary leakage syndrome in neonates. The degree of change of chest X-ray is basically consistent with the clinical stage of the disease, which can timely reflect the development and change of the disease.