基于“脑肠轴”理论探讨针灸治疗帕金森病抑郁的概述
An Overview of Acupuncture Treatment of Parkinson’s Depression Based on Brain-Gut Axis Theory
DOI: 10.12677/TCM.2022.112038, PDF,   
作者: 董兆玲, 白 妍*：黑龙江省中医药科学院，黑龙江 哈尔滨
关键词: 帕金森病；抑郁；脑肠轴；针灸；Parkinson’s Disease； Depression； Brain-Gut Axis； Acupuncture
摘要: 帕金森(Parkinson’s disease, PD)是一种常见的中老年慢性神经系统退行性疾病，研究显示，抑郁是PD患者主要的情绪障碍。PD患者伴发的抑郁又称帕金森病抑郁(PD with depression, PDD)，随着近年来深入研究，焦虑抑郁状态严重影响着患者生存质量。现代医学“脑肠轴”理论认为肠道菌群失调与帕金森病大脑中的病理关系互为因果。针灸通过调节脑肠轴可能成为治疗帕金森病抑郁的新靶点。该文从脑肠轴理论探讨针灸治疗帕金森病抑郁的研究思路，并为针灸治疗PDD提供更确切的临床理论依据，以期为临床治疗PDD提供更广阔的思路。
Abstract: Parkinson’s disease (PD) is a common chronic progressive neurodegenerative disease in the middle-aged and elderly. Studies have shown that depression is the main emotional disorder of PD patients. The depression associated with PD patients is also known as PD with depression (PDD). With the in-depth research in recent years, anxiety and depression state has a serious impact on the quality of life of patients. The “brain-gut axis” theory of modern medicine holds that the imbalance of intestinal flora and the pathological relationship in the brain of Parkinson’s disease are mutually causal. Acupuncture may be a new target for the treatment of depression in Parkinson’s disease by regulating the brain-gut axis. This paper discusses the research ideas of acupuncture and moxibustion in treating Parkinson’s disease depression from the theory of brain-gut axis, and provides a more exact clinical theoretical basis for acupuncture and moxibustion in treating PDD, in order to provide a broader idea for clinical treatment of PDD.
文章引用：董兆玲, 白妍. 基于“脑肠轴”理论探讨针灸治疗帕金森病抑郁的概述[J]. 中医学, 2022, 11(2): 252-257. https://doi.org/10.12677/TCM.2022.112038

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