颅内压监测仪在神经重症中的应用及进展

Application and Progress of Intracranial Pressure Monitor in Severe Neuropathy

摘要: 颅内压监测和指导下的治疗仍然是当代神经危重症治疗的基石，但临床应用中仍存在许多问题。颅内压监测从简单的测压到可连续反应病人颅内压(intracranial pressure, ICP)、脑灌注压(cerebral perfusion pressure, CPP)、平均动脉压(mean arterial pressure, MAP)、压力反应指数(pressure response index, PRx)等的变化，从孤立数值转变为ICP与脑代谢、脑温等神经功能的多模态监测研究，利用计算机实时数据处理得出最优灌注压，为及时调整治疗方案、保持良好脑灌注及脑代谢提供可靠依据，精准治疗神经外科疾病。本文现围绕ICP监测现状及相关脑代谢方面在神经重症中的临床应用及研究进展展开综述。

Abstract: Intracranial pressure (ICP) monitoring and treatment under the guidance of ICP are still the cornerstone of contemporary neurological critical treatment, but there are still many problems in clinical application. Intracranial pressure monitoring changed from simple pressure measurement to continuous response to the changes of ICP, CPP, MAP and PRx in patients, and from isolated values to multimodal monitoring of ICP and brain metabolism, brain temperature and other neurological functions. The optimal perfusion pressure was obtained by computer real-time data processing, which provides a reliable basis for timely adjustment of treatment plan, maintenance of good cerebral perfusion and brain metabolism, and accurate treatment of neurosurgical diseases. This article reviews the current situation of ICP monitoring and the clinical application and research progress of related brain metabolism in neurological severe diseases.