新生儿早发型败血症抗生素合理使用的研究进展
Research Progress on Rational Use of Antibiotics in Neonatal Early-Onset Septicemia
DOI: 10.12677/ACM.2022.123300, PDF,   
作者: 陈丽萍, 包 蕾*：重庆医科大学附属儿童医院新生儿科，国家儿童健康与疾病临床医学研究中心，儿童发育疾病研究教育部重点实验室，儿科学重庆市重点实验室，重庆
关键词: 新生儿；早发型败血症；抗生素；Neonate； Early-Onset Septicemia； Antibiotics
摘要: 新生儿败血症是指新生儿期细菌或真菌侵入血液导致的全身炎症反应综合征，早发型败血症一般发病时间 ≤ 3日龄。尽管这些年我国在新生儿管理方面获得了很大的进步，但新生儿早发型败血症仍然是新生儿发病和死亡的主要原因之一，尤其是早产儿和低出生体重儿。抗生素的治疗有效地降低了其死亡率，同时抗生素的不合理使用也可能带来不良预后，如新生儿坏死性小肠结肠炎、晚发型败血症、死亡等，故对新生儿早发型败血症进行合理的抗生素治疗显得尤为重要。下文将对新生儿早发型败血症的抗生素使用方面的研究进行探讨。
Abstract: Neonatal septicemia refers to the systemic inflammatory response syndrome caused by bacteria or fungi invading the blood during the neonatal period. The general onset time of early-onset septicemia is less than 3 days old. Although China has made great progress in neonatal management in recent years, neonatal early-onset septicemia is still one of the main causes of neonatal morbidity and death, especially of the premature and low birth weight infants. The treatment of antibiotics can effectively reduce the mortality rate. But the unreasonable use of antibiotics may also lead to poor prognosis, such as neonatal necrotizing enterocolitis, late-onset septicemia, death and so on. Therefore, reasonable antibiotic treatment of neonatal early-onset septicemia is particularly important. The following study will discuss the use of antibiotics in neonatal early-onset septicemia.
文章引用：陈丽萍, 包蕾. 新生儿早发型败血症抗生素合理使用的研究进展[J]. 临床医学进展, 2022, 12(3): 2092-2097. https://doi.org/10.12677/ACM.2022.123300

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