全膝关节置换术后感染的诊治的研究进展

Progress in the Diagnosis and Treatment of Periprosthetic Joint Infection after Total Knee Arthroplasty

摘要: 随着膝关节骨性关节炎患者逐渐增多，需行全膝关节置换术的人数也逐渐增加。全膝关节置换术作为终末期骨关节炎的有效治疗方式，能缓解关节疼痛、改善活动、提升患者生活质量。但全膝关节置换术后可能出现众多并发症，其中假体周围感染作为灾难性的并发症，不仅会延长住院时间，增加住院费用，甚至可能增加患者死亡风险，假体周围感染诊断及治疗对医生也是不小的挑战，其诊治中最重要的是早发现、早诊断、早治疗。本文搜索了PubMed、中国知网、万方医学网等数据库，对近年膝关节置换术后出现假体周围感染的危险因素、抗生素方案推荐、诊断标准、手术方式及各手术方案的适应症进行总结，希望能对临床假体周围感染的诊治提供帮助。

Abstract: As the number of patients with knee osteoarthritis grows, there are more and more patients requiring total knee arthroplasty. Total knee arthroplasty (TKA), as an effective treatment for end-stage osteoarthritis, can relieve pain, improve mobility of knee joint, and improve patients' quality of life. However, there may be many complications after total knee arthroplasty. Among them, periprosthetic joint infection, as a catastrophic complication, will not only prolong the hospital stay, increase the cost of hospitalization, but also increase the risk of death. The diagnosis and treatment of periprosthetic joint infection (PJI) is always a big challenge for doctors, and the most important things in its diagnosis and treatment are early detection, early diagnosis, and early treatment. This article searched PubMed, CNKI, WANFANG MED ONLINE and other databases to summarize the risk factors, antibiotic regimen recommendations, diagnostic criteria, surgical methods and indications for each surgical method for periprosthetic joint infection, hoping to provide help in the diagnosis and treatment of periprosthetic joint infection.