高尿酸血症与慢性肾衰竭的研究进展
Research Progress of Hyperuricemia and Chronic Renal Failure
DOI: 10.12677/ACM.2022.124421, PDF,   
作者: 郭思琦, 刘 玲*:重庆医科大学附属第二医院,泌尿肾病中心,重庆
关键词: 高尿酸血症慢性肾衰竭机制治疗Hyperuricemia Chronic Renal Failure Pathogenesis Treatment
摘要: 中国近年高尿酸血症(HUA)的发病率逐年升高。高尿酸血症可能通过促炎作用、损伤内皮细胞、引起血管病变等机制促进慢性肾衰竭(CRF)的发生发展,而慢性肾衰竭患者尿酸代谢异常也可导致尿酸水平升高。该文综述了高尿酸血症与慢性肾衰竭患者的相关性、作用机制、治疗进展,为临床医生提供参考。
Abstract: The incidence rate of hyperuricemia (hyperuricemia, HUA) has increased year by year in China. Hyperuricemia may promote the occurrence and development of chronic renal failure (CRF) by promoting inflammation, damaging endothelial cells and causing vascular lesions. Abnormal uric acid metabolism in patients with chronic renal failure can also lead to the increase of uric acid level. This paper reviews the correlation, mechanism and treatment progress between hyperuricemia and patients with chronic renal failure, so as to provide reference for clinicians.
文章引用:郭思琦, 刘玲. 高尿酸血症与慢性肾衰竭的研究进展[J]. 临床医学进展, 2022, 12(4): 2923-2927. https://doi.org/10.12677/ACM.2022.124421

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