碎裂QRS波在室性心律失常中的研究进展
Research Advances in Relationship between Fragmented QRS Complexes and Ventricular Arrhythmia
摘要: 碎裂QRS波(fragmented QRS complexes, fQRS波)是新的心电无创指标,可通过常规体表心电图获得。目前已有大量研究表明fQRS波与冠心病、心力衰竭、心肌病等疾病关系密切。本文就fQRS波在室性心律失常中的研究现状进行综述。
Abstract: Fragmented QRS complexes (fQRS) is a new non-invasive ECG index, which is achieved by conventional surface ECG. At present, many studies have shown that fQRS is related to coronary atherosclerotic heart disease, heart failure, cardiomyopathy and other diseases. This paper reviews research advances in relationship between fQRS and ventricular arrhythmia.
文章引用:朱璐, 吕娜, 黄艳, 肖春霞, 范咏梅. 碎裂QRS波在室性心律失常中的研究进展[J]. 临床医学进展, 2022, 12(4): 2973-2978. https://doi.org/10.12677/ACM.2022.124429

参考文献

[1] Das, M.K., Khan, B., Jacob, S., et al. (2006) Significance of a Fragmented QRS Complex versus a Q Wave in Patients with Coronary Artery Disease. Circulation, 113, 2495-2501. [Google Scholar] [CrossRef
[2] Das, M., Suradi, H., Maskoun, W., et al. (2008) Fragmented Wide QRS on a 12-Lead ECG: A Sign of Myocardial Scar and Poor Prognosis. Circulation: Arrhythmia and Electrophysiology, 1, 258-268. [Google Scholar] [CrossRef
[3] 郭继鸿. 碎裂QRS波[J]. 临床心电学杂志, 2008, 17(1): 60-68.
[4] 李国草, 刘艳军, 夏云龙, 高连君, 张树龙, 杨延宗, 董颖雪, 尹晓盟, 常栋. 经皮冠状动脉介入术对急性心肌梗死碎裂QRS波的影响及预后分析[J]. 中国全科医学, 2014, 17(18): 2083-2086.
[5] Tomasz, P., Radoslaw, L., Jacek, K., et al. (2018) Prognostic Significance of Complex Ventricular Arrhythmias Complicating ST-Segment Elevation Myocardial Infarction. American Journal of Cardiology, 121, 805-809. [Google Scholar] [CrossRef] [PubMed]
[6] Xu, S.B., Yang, L.H., Hong, D.H., et al. (2020) Predictive Value of Fragmented QRS for Ventricular Tachyarrhythmias in Patients with Acute Myocardial Infarction: A Meta-Analysis. European Journal of Clinical Investigation, 50, e13182. [Google Scholar] [CrossRef] [PubMed]
[7] Tanawat, A. and Rungroj, K. (2019) Fragmented QRS as a Predictor of In-Hospital Life-Threatening Arrhythmic Complications in ST-Elevation Myocardial Infarction Patients. Annals of Noninvasive Electrocardiology, 24, e12593. [Google Scholar] [CrossRef] [PubMed]
[8] Borja, I., Stefan, J., Stefan, A., et al. (2018) 2017 ESC Guidelines for the Management of Acute Myocardial Infarction in Patients Presenting with ST-Segment Elevation: The Task Force for the Management of Acute Myocardial Infarction in Patients Presenting with ST-Segment Elevation of the European Society of Cardiology (ESC). European Heart Journal, 39, 119-177. [Google Scholar] [CrossRef] [PubMed]
[9] Li, M., Wang, X., Mi, S.-H., et al. (2016) Short-Term Prognosis of Fragmented QRS Complex in Patients with Non-ST Elevated Acute Myocardial Infarction. Chinese Medical Journal, 129, 518-522. [Google Scholar] [CrossRef] [PubMed]
[10] Sha, J., Zhang, S., Tang, M., et al. (2011) Fragmented QRS Is Associated with All-Cause Mortality and Ventricular Arrhythmias in Patient with Idiopathic Dilated Cardiomyopathy. Annals of Noninvasive Electrocardiology, 16, 270-275. [Google Scholar] [CrossRef
[11] Kyohei, M., Teruo, N., Tsukasa, K., et al. (2021) Prognostic Impact of Multiple Fragmented QRS on Cardiac Events in Idiopathic Dilated Cardiomyopathy. Europace, 23, 287-297. [Google Scholar] [CrossRef] [PubMed]
[12] Soichiro, O., Kazufumi, N., Hiroshi, M., et al. (2020) New Appearance of Fragmented QRS as a Predictor of Ventricular Arrhythmic Events in Patients with Hypertrophic Cardiomyopathy. Circulation Journal, 84, 487-494. [Google Scholar] [CrossRef
[13] Hiroshi, M., Atsuyuki, W., Satoshi, K., et al. (2018) Identification of Electrocardiographic Risk Markers for the Initial and Recurrent Episodes of Ventricular Fibrillation in Patients with Brugada Syndrome. Journal of Cardiovascular Electrophysiology, 29, 107-114. [Google Scholar] [CrossRef] [PubMed]
[14] Naoya, K., Koichi, M., Yosuke, N., et al. (2016) Paced QRS Fragmentation Is Associated with Spontaneous Ventricular Fibrillation in Patients with Brugada Syndrome. Heart Rhythm, 13, 1497-1503. [Google Scholar] [CrossRef] [PubMed]
[15] Nathan, E., Geoffrey, D., Kevin, N., et al. (2022) Fragmented QRS Is Associated with Ventricular Arrhythmias in Heart Failure Patients: A Systematic Review and Meta-Analysis. Annals of Noninvasive Electrocardiology, 27, e12910. [Google Scholar] [CrossRef] [PubMed]
[16] Miyako, I., Hiroshi, T., Hiro, Y., et al. (2017) Fragmented QRS Is a Novel Risk Factor for Ventricular Arrhythmic Events after Receiving Cardiac Resynchronization Therapy in Nonischemic Cardiomyopathy. Journal of Cardiovascular Electrophysiology, 28, 327-335. [Google Scholar] [CrossRef] [PubMed]
[17] Lutfu, B., Macit, K., Hakan, K., et al. (2019) Presence of Fragmented QRS May Be Associated with Complex Ventricular Arrhythmias in Patients with Essential Hypertension. Journal of Electrocardiology, 55, 20-25. [Google Scholar] [CrossRef] [PubMed]
[18] Lutfu, B., Muzaffer, K., Mucahit, Y., et al. (2016) Fragmented QRS Complexes Are a Marker of Myocardial Fibrosis in Hypertensive Heart Disease. Turk Kardiyoloji Dernegi Arsivi, 44, 554-560.
[19] Vogels, R.J., Teuwen, C.P., Ramdjan, T., et al. (2017) Usefulness of Fragmented QRS Complexes in Patients with Congenital Heart Disease to Predict Ventricular Tachyarrhythmias. American Journal of Cardiology, 119, 126-131. [Google Scholar] [CrossRef] [PubMed]
[20] Ülker, K. and Hayati, E. (2020) Fragmented QRS May Be Associated with Complex Ventricular Arrhythmias in Mitral Valve Prolapse. Minerva Cardioangiologica, 68, 577-585. [Google Scholar] [CrossRef
[21] Huxley, R.R., Filion, K.B., Konety, S., et al. (2011) Meta-Analysis of Cohort and Case-Control Studies of Type 2 Diabetes Mellitus and Risk of Atrial Fibrillation. American Journal of Cardiology, 108, 56-62. [Google Scholar] [CrossRef] [PubMed]
[22] Priori, S.G., Blomström-Lundqvist, C., Mazzanti, A., et al. (2015) 2015 ESC Guidelines for the Management of Patients with Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death: The Task Force for the Management of Patients with Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death of the European Society of Cardiology (ESC). Endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC). European Heart Journal, 36, 2793-2867.
[23] Eren, H., Kaya, Ü., Öcal, L., et al. (2021) Presence of Fragmented QRS May Be Associated with Complex Ventricular Arrhythmias in Patients with Type-2 Diabetesmellitus. Acta Cardiologica, 76, 67-75. [Google Scholar] [CrossRef] [PubMed]
[24] Cho, H.J., Kim, N., Kim, H.J., et al. (2021) Effectiveness of a New Cardiac Risk Scoring Model Reclassified by QRS Fragmentation as a Predictor of Postoperative Cardiac Event in Patients with Severe Renal Dysfunction. BMC Cardiovascular Disorders, 21, Article No. 359. [Google Scholar] [CrossRef] [PubMed]
[25] Toukola, T., Junttila, M.J., Holmstrm, L.A., et al. (2018) Fragmented QRS Complex as a Predictor of Exercise-Related Sudden Cardiac Death. Journal of Cardiovascular Electrophysiology, 29, 55-60. [Google Scholar] [CrossRef] [PubMed]
[26] 张颖, 刘兴鹏, 闫倩, 黎旭, 于立群, 刘小慧, 董建增, 马长生. 健康成年人群碎裂QRS波群的检出与意义[J]. 临床心血管病杂志, 2011, 27(4): 299-302.
[27] Dinakrisma, A.A., Wijaya, I.P., Nasution, S.A., et al. (2019) The Role of Fragmented QRS (fQRS) as a Predictor of Major Adverse Cardiac Event within 30 Days in Acute Coronary Syndrome Patients: A Retrospective Cohort Study. Acta Medica Indonesiana, 51, 3-9.
[28] Dehghani, M.R., Shariati, A., Haghjou, A., et al. (2021) Prognostic Value of Fragmented QRS Complex in Patients with Acute Myocardial Infarction. Herz, 46, 285-290. [Google Scholar] [CrossRef] [PubMed]
[29] Xia, W., Feng, X.-Y. and Fragmented, Q.R.S. (2018) (fQRS) Complex Predicts Adverse Cardiac Events of ST-Segment Elevation Myocardial Infarction Patients Undergoing Percutaneous Coronary Intervention and Thrombolysis. Medical Science Monitor, 24, 4634-4640. [Google Scholar] [CrossRef
[30] 尹先犁, 严喜胜, 余志利. PCI术后新发碎裂QRS波对STEMI患者院内主要心血管不良事件的预测价值[J]. 中南医学科学杂志, 2021, 49(5): 568-571. [Google Scholar] [CrossRef
[31] Ozcan, S., Cakmak, H.A., Ikitimur, B., et al. (2013) The Prognostic Significance of Narrow Fragmented QRS on Admission Electrocardiogram in Patients Hospitalized for Decompensated Systolic Heart Failure. Clinical Cardiology, 36, 560-564. [Google Scholar] [CrossRef] [PubMed]
[32] Cetin, M.S., Ozcan, C.E.H., Canpolat, U., et al. (2016) Usefulness of Fragmented QRS Complex to Predict Arrhythmic Events and Cardiovascular Mortality in Patients with Noncompaction Cardiomyopathy. American Journal of Cardiology, 117, 1516-1523. [Google Scholar] [CrossRef] [PubMed]
[33] Yonezu, K., Shinohara, T., Sato, H., et al. (2021) Role of Fragmented QRS and Shanghai Score System in Recurrence of Ventricular Fibrillation in Patients with Early Repolarization Syndrome. Annals of Noninvasive Electrocardiology, 26, e12873. [Google Scholar] [CrossRef] [PubMed]
[34] Vandenberk, B., Robyns, T., Goovaerts, G., et al. (2017) Inferior and Anterior QRS Fragmentation Have Different Prognostic Value in Patients Who Received an Implantable Defibrillator in Primary Prevention of Sudden Cardiac Death. International Journal of Cardiology, 243, 223-228. [Google Scholar] [CrossRef] [PubMed]
[35] Sheng, Q.-H., Hsu, C.C., Li, J.-P., et al. (2018) Combining Fragmented QRS and TIMI Score for Predicting In-Hospital Short-Term Prognosis after Acute Myocardial Infarction. Journal of Zhejiang University Science B, 19, 349-353. [Google Scholar] [CrossRef
[36] Özyilmaz, S., Akgul, Ö., Uyarel, H., et al. (2017) Assessment of the Association between the Presence of Fragmented QRS and the Predicted Risk Score of Sudden Cardiac Death at 5 Years in Patients with Hypertrophic Cardiomyopathy. The Anatolian Journal of Cardiology, 18, 54-61. [Google Scholar] [CrossRef