颅脑创伤后进展性出血性损伤与创伤性凝血病的关系
Relationship between Progressive Hemorrhagic Injury after Traumatic Brain Injury and Acute Traumatic Coagulopathy
DOI: 10.12677/ACM.2022.124459, PDF,   
作者: 李嗣煜：青海大学研究生院，青海 西宁；李坤正*：青海大学附属医院神经外科，青海 西宁
关键词: 颅脑创伤；进展性出血性损伤；急性创伤性凝血病；Craniocerebral Trauma； Progressive Hemorrhagic Injury； Acute Traumatic Coagulopathy
摘要: 颅脑创伤后进展性出血性损伤(PHI)与急性创伤性凝血病(ATC)相关，使颅脑创伤患者不良预后的发生率增加。本文就组织因子假说、蛋白质C途径和血小板减少症等机制在PHI发生发展中的作用进行综述。同时着重讨论PHI与ATC的联系，探讨颅脑创伤患者PHI的预防措施及展望。
Abstract: Progressive hemorrhagic injury (PHI) after traumatic brain injury is associated with acute traumatic coagulopathy (ATC), increasing the incidence of adverse outcomes in patients with traumatic brain injury. This article reviews the role of tissue factor hypothesis, protein C pathway and thrombocytopenia in the development of PHI. At the same time, the relationship between PHI and ATC is discussed, and the preventive measures and prospects of PHI in patients with brain trauma are discussed.
文章引用：李嗣煜, 李坤正. 颅脑创伤后进展性出血性损伤与创伤性凝血病的关系[J]. 临床医学进展, 2022, 12(4): 3185-3190. https://doi.org/10.12677/ACM.2022.124459

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