溃疡性结肠炎合并结直肠息肉的危险因素分析

Analysis of Risk Factors of Ulcerative Colitis Complicated with Colorectal Polyps

摘要: 目的：分析溃疡性结肠炎(Ulcerative colitis, UC)合并结直肠息肉患者的临床特点，为预防结直肠癌(Colorectal cancer, CRC)的发生提供依据。方法：选取2019年1月至2021年12月于我院住院诊治的100例UC患者为研究对象，根据肠镜检查结果分为息肉组(29例)和非息肉组(71例)。经单因素及多因素Logistic回归分析溃疡性结肠炎患者合并结直肠息肉的危险因素。结果：单因素及多因素Logistic回归分析显示，发病年龄(OR = 1.059)、病程(OR = 1.073)、病变程度(OR = 3.803)是UC患者息肉形成的危险因素。结论：应密切监测发病年龄较大、病程较长、病变较严重的患者，并在早期内镜检查中对息肉进行积极的干预，以降低结直肠癌发生的风险，改善其长期预后。

Abstract: Objective: To analyze the clinical characteristics of patients with ulcerative colitis (UC) complicated with colorectal polyps, and to provide basis for the prevention of colorectal cancer (CRC). Methods: 100 patients with UC hospitalized in our hospital from January 2019 to December 2021 were se-lected as the research object. According to the results of enteroscopy, they were divided into polyp group (29 cases) and non polyp group (71 cases). The risk factors of colorectal polyps in patients with ulcerative colitis were analyzed by univariate and multivariate logistic regression. Results: Univariate and multivariate logistic regression analysis showed that age of onset (OR = 1.059), course of disease (OR = 1.073) and degree of lesion (OR = 3.803) were the risk factors of polyp for-mation in patients with UC. Conclusion: Patients with older onset age, longer course of disease and more serious lesions should be closely monitored, and polyps should be actively intervened in early endoscopy, so as to reduce the risk of colorectal cancer and improve its long- term prognosis.