EUS-FNA对胰腺实性占位诊断价值及影响因素分析

Diagnostic Value and Influencing Factors of EUS-FNA in Pancreatic Solid Masses

摘要: 目的：探讨内镜超声引导下细针抽吸(EUS-FNA)对胰腺实性占位诊断价值及相关影响因素分析。方法：回顾性分析2017年1月至2022年1月在我院行EUS-FNA的102例患者的临床和病理资料，纳入性别、年龄、病灶位置、病灶大小、穿刺针型号、穿刺次数、抽吸负压、糖类抗原199水平和癌胚抗原水平等因素进行分析。结果：EUS-FNA诊断胰腺实性占位的敏感度为92.0% (81/88)，特异度为92.9% (13/14)，诊断准确率为92.2% (94/102)。EUS-FNA在年龄 ≥ 60岁，病灶位于胰体尾部患者的诊断准确率高于年龄 < 60岁、病灶位于胰头部的患者(P < 0.05)。结论：EUS-FNA对胰腺实性占位具有重要的鉴别诊断价值。EUS-FNA对胰腺实性占位的诊断价值可能受年龄和病灶位置的影响。

Abstract: Objective: To investigate the diagnostic value of endoscopic ultrasound-guided fine needle aspira-tion (EUS-FNA) in pancreatic solid masses and analyze the related influencing factors. Method: The clinical and pathological data of 102 patients receiving EUS-FNA from January 2017 to January 2022 were collected. The gender, age, lesion location, lesion size, size of puncture needle, the number of needle passes, negative suction pressure, carbohydrate antigen 199 level and carcinoembryonic antigen level were retrospectively analyzed. Result: The sensitivity, specificity and diagnostic accu-racy of EUS-FNA were 92.0% (81/88), 92.9% (13/14), 92.2% (94/102), respectively. The diagnostic accuracy of EUS-FNA in patients aged ≥60 years with lesions in the body and tail of the pancreas was higher than that in patients aged <60 years with lesions in the head of the pancreas (P < 0.05). Con-clusion: EUS-FNA has a high value in the differential diagnosis of pancreatic solid mass. The diag-nostic value of EUS-FNA for pancreatic solid masses may be affected by age and lesion location.